Results 121 to 130 of about 246,372 (396)

Different Influences of Hematocrit on the Results of Two Point-Of-Care Platelet Function Tests, the VerifyNow Assay and Multiple Electrode Platelet Aggregometry

PLoS ONE, 2014
Objective Previous studies have reported a considerable association between the VerifyNow (Accumetrics, San Diego, CA, USA) P2Y12 assay results and hematocrit.
Y. Kim, J. Suh, Jin Joo Park, I. Oh, C. Yoon, Young-Seok Cho, T. Youn, I. Chae, D. Choi   +8 more
semanticscholar   +1 more source

A simplified particulate model for coarse-grained hemodynamics simulations [PDF]

, 2010
Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models either involve
A. R. Pries, F. Janoschek, F. Toschi, J. Harting, J. Wu, M. P. Allen, S. Succi, T. W. Secomb, Y. C. Fung   +8 more
core   +2 more sources

Use of PopPK and E‐R Analyses toward Explaining Causal Link Between ADAMTS13 in Recombinant vs. Plasma‐Based Therapies and Clinical Effects in cTTP

Clinical Pharmacology &Therapeutics, EarlyView.
Congenital thrombotic thrombocytopenic purpura (cTTP) is an ultra‐rare, potentially life‐threatening condition caused by a deficiency of the blood enzyme ADAMTS13. Until now, ADAMTS13 replacement has been achieved with infusions of plasma or plasma‐based therapies (PBT).
Munjal Patel, Huijuan Xu, Olivier Barriere, Paul Diderichsen, Parth Patwari, Andy Z. X. Zhu, Jean François Marier, Thomas Peyret, Linda T. Wang, Björn Mellgård, Wenping Wang, Indranil Bhattacharya   +11 more
wiley   +1 more source

THE EFFECT OF VARIOUS ANTICOAGULANTS ON THE SPECIFIC GRAVITY OF BLOOD AND OF PLASMA, AND ON THE HEMATOCRIT [PDF]

, 1949
Paul L. McLain, Cornelia Ruhe, George J. Pastorius   +2 more
openalex   +1 more source

Iron Deficiency in HbSC Disease Treated With Repetitive Phlebotomy Is Associated With Fewer Sickle Cell Disease‐Related Complications

American Journal of Hematology, EarlyView.
Marissa J. M. Traets, Aida S. Kidane Gembremeskel, Jennifer Eijkelenboom‐Bos, Birgitte A. van Oirschot, Sigrid van der Veen, Henk Russcher, Wouter W. van Solinge, Mandy N. Lauw, Erfan Nur, Bart J. Biemond, Marjon H. Cnossen, Anita W. Rijneveld, Richard van Wijk, Eduard J. van Beers, Minke A. E. Rab   +14 more
wiley   +1 more source

Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First‐in‐Human Studies in Healthy Participants and Patients

Clinical Pharmacology &Therapeutics, EarlyView.
The investigational agent osivelotor, a small molecule hemoglobin (Hb) modifier in development for the treatment of sickle cell disease (SCD), acts by increasing Hb‐oxygen affinity and inhibiting the polymerization of sickle Hb. We report safety, pharmacokinetic (PK), and pharmacodynamic (PD) data from the first two phase 1 clinical trials of ...
Eleanor A. Lisbon, R. Clark Brown, Andrew Redfern, Ken Duchin, Aline Barth, Erika S. Roberts, Polo Gaputan, Kobina Dufu, Arthur Lo, Mira Patel Pochron, David R. Archer, Wai Chin, Karena Kong, Carla B. Washington, Adeyemi Adenola, Eric I. Zimmerman   +15 more
wiley   +1 more source

Quality control improvement at Jana DCS Sdn. Bhd. [PDF]

, 2020
Jana DCS Sdn. Bhd. is one of the companies that run the service of air conditioning system supply in Nusajaya, Johor, Malaysia. Quality improvement is one of the most important part when talking about a company, mostly companies that operate in service ...
Abd Wahab, Muhammad Badrul Amin, Mahmood, Salwa, Mohamad Rus, Mohamad Arif, Mustar, Muhamad Radzi, Raja Mamat, Tengku Nur Azila   +4 more
core  

Estimation of Plasma Volume by Machine Learning to Improve the Interpretation of the Athlete Biological Passport

Drug Testing and Analysis, EarlyView.
A new machine learning model for plasma volume (PV) estimation was applied within the ABP framework. PV estimation was applied through visual displays or corrected ABP thresholds. With a favorable assessment from ABP experts, these results support further application of this model in the presence of specific confounding factors.
Bastien Krumm, Laura Lewis, Jakob Mørkeberg, Yorck Olaf Schumacher, Giuseppe d'Onofrio, Basile Moreillon, Raphael Faiss   +6 more
wiley   +1 more source

The "Tissue" Tension of Oxygen and Its Relation to Hematocrit and Erythropoiesis [PDF]

, 1968
Eivind B. Thorling, Allan J. Erslev
openalex   +1 more source

Effects of aggregation on the blood flow velocity field measured by a μPIV based technique [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Balabani, S, Dusting, J, Kaliviotis, E   +3 more
core