P2‐165: HEMATOLOGIC SAFETY OF A BRAIN PENETRATING ERYTHROPOIETIN‐TRANSFERRIN RECEPTOR ANTIBODY FUSION PROTEIN IN A MOUSE MODEL OF ALZHEIMER'S DISEASE [PDF]
, 2019 Jiahong Sun +9 more
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Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies [PDF]
, 2022 Abdullah O. Khan +26 more
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Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Dysregulation of HOXA genes in acute myeloid leukemia and targeted therapy
npj Precision OncologyThe abnormal expression of the HOXA genes is intricately associated with the pathogenesis and progression of acute myeloid leukemia (AML), as these genes are crucial in regulating cellular differentiation and proliferation during normal hematopoiesis. In
Wusixian Huang +4 more
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An interview with Dan L. Longo, Section Editor of the Malignant hematological diseases section [PDF]
, 2013 Dan L. Longo
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Hematological parameters and antibody titers to new castle diseases and avian influenza on extensive and semi-intensive system [PDF]
, 2021 Ismoyowati Ismoyowati +2 more
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Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Infections of Febrile Neutropenic Patients in Malignant Hematological Diseases (Second Study Period) [PDF]
, 2005 László Rókusz, László Liptay
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Chronic Kidney Disease of Unknown Etiology (CKDu) in Sri Lanka: Hematological Changes and Pro-Inflammation Suggest Likely Predictors of Advance Disease, as Renal Outcomes Show Prevalent Normoalbuminuria [PDF]
, 2021 S. H. Nandana P. Gunawickrama +3 more
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