Results 121 to 130 of about 9,342,565 (376)

Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System. [PDF]

open access: yes, 2018
Chimeric antigen receptor (CAR) T cell therapy has proven clinically beneficial against B cell acute lymphoblastic leukemia and non-Hodgkin's lymphoma. However, suboptimal clinical outcomes have been associated with decreased expansion and persistence of
Avanzi, Mauro P   +10 more
core   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

open access: yesAdvanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang   +6 more
wiley   +1 more source

Analyzing cell mechanics in hematologic diseases with microfluidic biophysical flow cytometry.

open access: yesLab on a Chip, 2008
Pathological processes in hematologic diseases originate at the single-cell level, often making measurements on individual cells more clinically relevant than population averages from bulk analysis.
Michael J. Rosenbluth   +2 more
semanticscholar   +1 more source

Powder Metallurgy Preparation of Metastable β Ti–Cr–Ge Alloys for Medical Applications

open access: yesAdvanced Engineering Materials, EarlyView.
This study develops metastable β Ti–Cr–Ge alloys using powder metallurgy for biomedical implants. The Ti–10Cr–2Ge alloy exhibits superior mechanical performance with high yield strength (>1100 MPa), low Young's modulus (<85 GPa), and excellent strain hardening behavior.
Teddy Sjafrizal   +3 more
wiley   +1 more source

Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma

open access: yesDiscover Oncology
Purpose To evaluate the efficacy of next-generation sequencing (NGS) in minimal-residual-disease (MRD) monitoring in Chinese patients with multiple myeloma (MM). Methods This study analyzed 60 Chinese MM patients. During MRD monitoring in these patients’
Mo Zhou   +15 more
doaj   +1 more source

Hematologic Diseases. New Directions in Therapy [PDF]

open access: bronze, 1977
Peter Curt Ungaro, Bruce R. Canaday
openalex   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

P403: HIGH EXPRESSION OF STAT5 INDICATES POOR PROGNOSIS IN B CELL ACUTE LYMPHOBLASTIC LEUKEMIA

open access: yesHemaSphere, 2023
Xiuli Xu   +6 more
doaj   +1 more source

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