Results 141 to 150 of about 173,076 (340)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Prevalence of Depression in Patients with Hematologic Diseases in Marrakesh, Morocco: A Single Center Experience. [PDF]
J Community Hosp Intern Med Perspect, 2023 Lahlimi FZ +4 more
europepmc +1 more source
5. Hematologic Diseases 2) Coagulation and Fibrinolytic Systems
, 2008 Masahide Yamazaki +2 more
openalex +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Clinical application value of metagenomic second-generation sequencing technology in hematologic diseases with and without transplantation. [PDF]
Front Cell Infect Microbiol, 2023 Zhang X, Wang F, Yu J, Jiang Z.
europepmc +1 more source
Association between Novel Hematological Indices and Measures of Disease Activity in Patients with Rheumatoid Arthritis [PDF]
, 2023 Jung‐Yoon Choe +2 more
openalex +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Myelomatous Pleural Effusion [PDF]
Multiple myeloma (MM) is a common hematologic malignancy. Pleural effusion is a rare presenting feature of multiple myeloma which carries a poor prognosis.
شیردل, عباس +3 more
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