Results 141 to 150 of about 9,376,530 (330)

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

Advanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng, Shiqiong Lei, Yiwei Zeng, Lian Chen, Jingqu Chen, Wei Fu, Yu Chen, Xinping Hu, Jing Wang, Meiyuan Jin, Zhichen Liu, Xiaofang Dai, Lei Liu, Wenshan He, Jiajing Zhou, Zhixing Lin, Frank Caruso, Jinghua Ren   +17 more
wiley   +1 more source

Hematological Risk Factors for Coronary Heart Disease [PDF]

, 2002
M.A.F. El‐Hazmi
openalex   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

The Impact of Hematologic Disorders on the Severity of Cerebral Venous Sinus Thrombosis: A Comparative Study

Clinical and Applied Thrombosis/Hemostasis
Hematologic diseases are considered important contributors to cerebral venous sinus thrombosis (CVST) cases. This retrospective study aims to compare the difference of the clinical and radiological characters between CVST patients with and without ...
Mengqi Wang MD, Xiangqian Huang MD, Yuchuan Ding Ph.D, Xunming Ji MD, PhD, Ran Meng MD, PhD   +4 more
doaj   +1 more source

Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease [PDF]

, 2002
Blanca Scheijen, James D. Griffin
openalex   +1 more source

A Systematic Approach to Analyze T Cell Migration: Application to Mouse Melanoma Tumors

Advanced Therapeutics, EarlyView.
The results show that a minimum of two migration speeds can be rigorously identified from the data with cells switching between a fast, persistent migratory state, and a slow, random migration state. These results will help in identifying genetic factors that influence rapid migration, among other applications, such as quality control for CAR‐T cell ...
Nikolaos Memmos, Jason S. Mitchell, Brian T. Fife, David Masopust, David J. Odde   +4 more
wiley   +1 more source

Clinical Implementation of β-Tubulin Gene-Based Aspergillus Polymerase Chain Reaction for Enhanced Aspergillus Diagnosis in Patients with Hematologic Diseases: A Prospective Observational Study. [PDF]

J Fungi (Basel), 2023
Lee R, Kim WB, Cho SY, Nho D, Park C, Yoo IY, Park YJ, Lee DG.   +7 more
europepmc   +1 more source

Outcome in hemoglobin SC disease: A four‐decade observational study of clinical, hematologic, and genetic factors [PDF]

, 2002
Darleen Powars, Alan L. Hiti, Emily Ramicone, Cage S. Johnson, Linda S. Chan   +4 more
openalex   +1 more source

Comparison of the Hemostatic Efficacy of Pathogen-Reduced Platelets vs Untreated Platelets in Patients With Thrombocytopenia and Malignant Hematologic Diseases: A Randomized Clinical Trial

JAMA Oncology, 2018
F. Garban, A. Guyard, H. Labussière, C. Bulabois, T. Marchand, C. Mounier, D. Caillot, J. Bay, V. Coiteux, A. Schmidt-Tanguy, C. Le Niger, C. Robin, P. Ladaique, S. Lapusan, E. Deconinck, C. Rolland, A. Foote, A. François, C. Jacquot, R. Tardivel, P. Tiberghien, J. Bosson   +21 more
semanticscholar   +1 more source

HERV‐K TM Subunit Elicits CD8+ T Cell Anergy and Tumor Immune Evasion via Targeting CD3 Coreceptor ε in AML and PDAC

Advanced Science, EarlyView.
Novel viral immune checkpoint K‐TM subunit is aberrantly expressed in CD8+ T cells and enriched in sera of cancer patients, inducing CD8+ T cell anergy and eliciting potent tumor immune escape in mouse model. Mechanistically, K‐TM directly targets and induces the phosphorylation of CD3ε receptor.
Mengyuan Li, Shuwen Zheng, Qinyuan Gong, Zhaoxing Wu, Wen Lei, Wanyue Cao, Ping Wang, Xuzhao Zhang, Wenbin Qian, Yun Liang, Ying Lu, Fenglin Li, Qi Zhang, Rongzhen Xu   +13 more
wiley   +1 more source