Results 231 to 240 of about 9,342,565 (376)

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Computed tomography findings of pneumonia resistant to empirical therapy in patients with hematologic diseases. [PDF]

Radiol Bras
Giuliani L, Landini N, Masci GM, Palladino S, Panebianco V, Raponi G, Rocco AD, Gentile G, Catalano C.   +8 more
europepmc   +1 more source

BCOR gene alterations in hematologic diseases.

Blood, 2021
Sportoletti P, Sorcini D, Falini B.
europepmc   +1 more source

Laparoscopic Appendectomy for Acute Appendicitis Complicated by Pancytopenia in Two Patients with Hematologic Diseases. [PDF]

J Anus Rectum Colon, 2021
Kojima K, Nakamura T, Habiro T, Waraya M, Hayashi K, Ishii KI.   +5 more
europepmc   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

Advanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li, Ying Qu, Bingyang Chu, Tingkui Wu, Meng Pan, Dong Mo, Lang Li, Yang Ming, Yun Yang, Meng Wang, Xinlong He, Zhiyong Qian   +11 more
wiley   +1 more source

CEBPA bZIP in-frame mutations in acute myeloid leukemia: prognostic and therapeutic implications

Blood Cancer Journal
Fenghong Zhang, Zhen Shen, Jundan Xie, Jingren Zhang, Qian Wu, Rui Jiang, Xiangyu Zhao, Xiaofei Yang, Suning Chen   +8 more
doaj   +1 more source

CEBPA double mutations associated with ABO antigen weakness in hematologic diseases. [PDF]

Blood Adv
Choi SJ, Kim HK, Suh EJ, Kwon SS, Shin S, Lee ST, Kim S.   +6 more
europepmc   +1 more source

Human Schlafen 14 Cleavage of Short Double‐Stranded RNAs Underpins its Antiviral Activity

Advanced Science, EarlyView.
SLFN14 is associated with human diseases. SLFN14 is found to cleave RNAs containing short duplexes. The cryo‐EM structures of SLFN14 and SLFN14‐hairpin RNA complex reveal that SLFN14 assembles into a ring‐like dimer; two RNase domains form an RNA‐binding groove accommodating a hairpin RNA.
Mengyun Li, Dapeng Sun, Wei Hao, Hua Fu, Yueli Zhang, Zhijian Li, Bo Qin, Yumei Wang, Sheng Cui   +8 more
wiley   +1 more source

Survey of Clinical Practice in Chronic Myeloproliferative Neoplasms in Croatia: A Study by the MPN Working Group Party of the Croatian Cooperative Group for Hematologic Diseases (KROHEM). [PDF]

J Clin Med
Krecak I, Lucijanic M, Kusec R.
europepmc   +1 more source