Results 261 to 270 of about 9,342,565 (376)
Erythrocyte Antibodies in AIDS are associated with mycobacteriosis and hypergammaglobulinemia [PDF]
A. Matuschke+21 more
core +1 more source
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long+17 more
wiley +1 more source
The existence of Pin1 and Notch1 crosstalk is identified and verified in HCC, and the crucial function of this crosstalk in sustaining the aggressive phenotypes of CSCs and radioresistance. A biomimetic nanovesicle is now developed to block the crosstalk between Pin1 and Notch1 for inducing CSCs differentiation and sensitizing HCC radiotherapy ...
Hongmei Cao+9 more
wiley +1 more source
Escherichia coliPyomyositis: An Emerging Infectious Disease among Patients with Hematologic Malignancies [PDF]
Karen J. Vigil+7 more
openalex +1 more source
PFKFB2‐Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury
Paraquat (PQ) or lipopolysaccharide (LPS) exposure activates the HIF‐1α–PFKFB2 pathway, driving glycolysis in dendritic cells (DCs). This metabolic shift enhances DC maturation and immune activation, exacerbating acute lung injury (ALI). This study demonstrates that PFKFB2‐driven glycolytic reprogramming in DCs plays a critical role in the pathogenesis
Ding Yuan+17 more
wiley +1 more source
Personalized Treatment for Hematologic Diseases in Europe: An EHA Position Paper. [PDF]
Jäger U, Kapitein P, Gribben J.
europepmc +1 more source
Hematologic, biochemical, and cardiopulmonary effects of
Jane A. Little+11 more
openalex +1 more source
The findings suggest that the combination of PIM‐2 and PARP1 inhibitors can induce MICA expression on MM cells, thereby activating NK cells through NKG2D binding. This process may restore NK cell function and serve as a potential therapeutic approach for MM patients. Abstract While immunogenic death in tumor cells activates specific anti‐tumor T cells,
Zhaoyun Liu+6 more
wiley +1 more source
Candidosis in Children with Onco-Hematological Diseases in Chennai, South India
C. P. Girish Kumar+3 more
openalex +2 more sources