Results 271 to 280 of about 169,813 (342)

[Therapeutic effects of glucocorticoids in patients with hematologic diseases with neutropenia and severe pneumonia classified by the PSI scores]. [PDF]

Zhonghua Xue Ye Xue Za Zhi
Xue SF, Ren JH, Chen LJ, Zhao XQ, Yang T, Hu JD.   +5 more
europepmc   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Treatment-Related Risk Factors for Adverse Outcomes of COVID-19 in Patients Treated for Lymphoid Malignancies in the Pre-Omicron Era-A Study of KroHem, the Croatian Group for Hematologic Diseases. [PDF]

Biomedicines
Aurer I, Jakšić O, Bašić-Kinda S, Mrđenović S, Ostojić-Kolonić S, Lozić D, Holik H, Novaković-Coha S, Berneš P, Krečak I, Morić-Perić M, Narančić M, Mitrović Z, Valković T.   +13 more
europepmc   +1 more source

Multifunctional Fluorescent Microgel‐Embedded Hydrogels for Temperature and X‐Ray Sensing

Advanced Science, EarlyView.
In this study, the application of a multifunctional fluorescent hydrogel based on AIE microgels, integrated with machine‐learning algorithms for the detection of temperature and X‐rays is prestented. This innovative platform not only simultaneously elevates temperature and X‐ray sensing performance but also preserves outstanding mechanical robustness ...
Hao Jiang, Luyao Wang, Li Jiang, Yajie Wang, Jinlong Zhang, Mingyuan Pan, Rui Hu, Jun Li, Chouwang Li, Chan Kyung Kim, Hong Chen, Liang Hu   +11 more
wiley   +1 more source

Folic Acid‐Modified Ginger‐Derived Exosome‐Like Nanoparticles Co‐Delivering Sunitinib Suppress Renal Cell Carcinoma via PI3K‐Akt Pathway Inhibition, P‐gp Downregulation, and Macrophage Reprogramming

Advanced Science, EarlyView.
FPD‐GELNs co‐deliver Su and bioactive components. This active‐passive dual‐targeting strategy suppresses the progression of RCC through the following mechanisms: 1) inhibition of the PI3K‐Akt signaling pathway; 2) downregulation of ABCB1/P‐gp to enhance the chemosensitivity of RCC to Su; and 3) reprogramming of macrophages toward M1 polarization and ...
Haoyu Xu, Daixing Hu, Shixue Liu, Lei Yang, Junwu Li, Yuanyuan Bai, Guozhi Zhao, Wei Tang, Li Jiang   +8 more
wiley   +1 more source

A Comprehensive Study on the Hematological Progression of Sickle Cell Disease Patients with COVID-19 at the Center for Research and Control of Sickle Cell Disease, Bamako.

Aldiouma Guindo, Yéya dit Sadio Sarro, Sékou Kene, Boubacari Ali Touré, Abdulmalik Koya, I Keita, Yaya Ibrahim Coulibaly, Mody Coulibaly, Mohamed Ag Baraïka, M Coulibaly, Mariam Kanta, Traore Aissata, Pierre Guindo, Oumar Tessougue, Drissa Diabaté, Mounirou Baby, Emilie Lauressergues, Véronique Teyssié, Christophe Przybilski, Béatrice Garrette   +19 more
openalex   +1 more source

Glucocorticoid Receptor Activation Reprograms NK Cells to Drive AREG‐Mediated Immunosuppression: A Pan‐Cancer Role for AREG

Advanced Science, EarlyView.
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei, Guirong Liang, Rui zeng, Yuancheng Li, Anlan Hong, Hongsheng Wang, Suying Feng, Yan Wang, Yetao Wang   +8 more
wiley   +1 more source

Posterior reversible encephalopathy syndrome in pediatric hematologic-oncologic disease: literature review and case presentation.

, 2014
Mohammad Thaghi Arzanian, Bibi Shahin Shamsian, Parvaneh Karimzadeh, Kajiyazdi Mohammad, Fatemeh Malek, Mohammad Hammoud   +5 more
openalex   +1 more source