Results 31 to 40 of about 9,376,530 (330)

Myeloid-Derived Suppressor Cells in Hematologic Diseases: Promising Biomarkers and Treatment Targets

HemaSphere, 2019
Myeloid-derived suppressor cells (MDSC) are a heterogeneous group of immature myeloid cells that exist at very low numbers in healthy subjects but can expand significantly in malignant, infectious, and chronic inflammatory diseases.
N. Bizymi, Suncica Bjelica, A. Kittang, S. Mojsilović, M. Velegraki, C. Pontikoglou, M. Roussel, Elisabeth Ersvær, J. Santibañez, M. Lipoldová, H. Papadaki   +10 more
semanticscholar   +1 more source

Machine Learning for Diagnosis of Hematologic Diseases in Magnetic Resonance Imaging of Lumbar Spines

Scientific Reports, 2019
We aimed to assess feasibility of a support vector machine (SVM) texture classifier to discriminate pathologic infiltration patterns from the normal bone marrows in MRI.
E. Hwang, Joon-Yong Jung, S. Lee, Sung‐Eun Lee, W. Jee   +4 more
semanticscholar   +1 more source

Introduction to a review series on emerging immunotherapies for hematologic diseases.

Blood, 2018
Immune therapies are fast becoming paradigm-changing treatment options for patients with hematologic cancers. The field has grown exponentially as it expands to nonmalignant blood diseases. This Perspective article introduces the review series describing
S. Paczesny, S. Pavletic, C. Bollard
semanticscholar   +1 more source

Long and persistent COVID-19 in patients with hematologic malignancies: from bench to bedside

Current Opinion in Infectious Diseases, 2022
Purpose of review Cancer patients, especially those with hematologic malignancies, are at increased risk for coronavirus disease 2019 (COVID-19)-related complications and mortality.
Justin C. Laracy, M. Kamboj, S. Vardhana
semanticscholar   +1 more source

Patient‐reported physical well‐being predicts good long‐term survival of hematopoietic stem cell transplantation

Cancer Medicine
Aim This study aimed to explore the association between patient‐reported items at different time points after hematopoietic stem cell transplantation (HSCT) and long‐term survival. Methods We conducted a study with 144 allogeneic HSCT patients, following
Yin Lu, Tao You, Qin Ma, Weijuan Wang, Jiaqian Qi, Pan Yang, Yaya Song, Jia Chen, Jianhong Fu, Yongqin Ge, Xiaming Zhu, Depei Wu   +11 more
doaj   +1 more source

Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma

Biomarker Research, 2022
Patients with relapsed/refractory early T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) respond poorly to traditional therapy and have dismal prognosis.
Hai-ping Dai, Wei Cui, Qing-ya Cui, Wen-juan Zhu, Hui-min Meng, Min-qing Zhu, Xia-ming Zhu, Lin Yang, De-pei Wu, Xiao-wen Tang   +9 more
doaj   +1 more source

Experience of Peripherally Inserted Central Venous Catheter in Patients with Hematologic Diseases

Internal medicine, 2017
Objective Although use of the peripherally inserted central venous catheter (PICC) has become increasingly common, there are few reports of PICCs used for patients with hematologic diseases.
Yoshinori Hashimoto, T. Fukuta, J. Maruyama, H. Omura, Takayuki Tanaka   +4 more
semanticscholar   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Increased Epstein‒Barr virus reactivation following prophylaxis for cytomegalovirus infection after haploidentical haematopoietic stem cell transplantation

Journal of Hematology & Oncology
Letermovir (LTV) prophylaxis is effective in reducing the incidence of clinically significant cytomegalovirus (CMV) infection (cs CMVi) after allogeneic haematopoietic stem cell transplantation (allo-HSCT).
Xin Kong, Ziyi Xu, Yanjun Wu, Xiaowen Tang, Shengli Xue, Miao Miao, Yue Han, Ying Wang, Suning Chen, Aining Sun, Huiying Qiu, Depei Wu, Ye Zhao, Feng Chen   +13 more
doaj   +1 more source

Preemptive inotuzumab ozogamicin eradicated measurable residual disease in Ph‐negative acute lymphoblastic leukemia relapsed post CD19 CART therapy

Clinical Case Reports, 2023
Key Clinical Message There are no reports of application of inotuzumab ozogamicin (InO) for the treatment of MRD in r/r B‐ALL. We firstly report the efficacy of InO for a patient experienced morphological relapse after HSCT and molecular relapse after ...
Si‐Man Huang, Chao‐Ling Wan, Han‐Yu Cao, Yan‐Yan Li, Chong‐Sheng Qian, Hai‐Xia Zhou, Ming‐Zhu Xu, Xiao‐Hui Hu, Lan Dai, Hai‐Ping Dai, Sheng‐Li Xue   +10 more
doaj   +1 more source