Results 71 to 80 of about 87,295 (197)

Radio‐Activated Selenium‐Doped Janus Ag/Ag2SexSy Nanoparticles for Precise Cancer NIR‐II Fluorescence Imaging and Radiosensitization Therapy

open access: yesAdvanced Science, EarlyView.
A new kind of selenium‐doped Ag/Ag2S Janus nanoparticles (Ag/Ag2SexSy JNPs) is reported as radio‐responsive probes for specifically hydrogen peroxide (H2O2)‐activated cancer imaging and enhanced radiosensitization, offering a promising approach for precision cancer theranostics.
Kang Zhu   +12 more
wiley   +1 more source

Genetically Engineered IL12/CSF1R‐Macrophage Membrane‐Liposome Hybrid Nanovesicles for NIR‐II Fluorescence Imaging‐Guided and Membrane‐Targeted Mild Photothermal‐Immunotherapy of Glioblastoma

open access: yesAdvanced Science, EarlyView.
A theranostic nanoplatform is formulated with NIR‐II emissive lipophilic cyanine dye IRC18 to intercalate into genetically engineered IL12/CSF1R‐macrophage membrane‐liposome hybrid nanovesicles, which assists to achieve blood–brain barrier crossing, glioblastoma targeting, NIR‐II fluorescence imaging, image‐guided membrane‐targeted mild photothermal ...
Pengfei Chen   +10 more
wiley   +1 more source

Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury

open access: yesAdvanced Science, EarlyView.
Dipyridamole acts as a clinically used compound to suppress ferroptosis. Dipyridamole down‐regulates the expression of RNF126, which is an E3 ligase to ubiquitinate SLC7A11 for proteasome degradation. The deficiency of SLC7A11 largely abolishes the protective role of dipyridamole both in vitro and in vivo.
Xiao Zhuang   +22 more
wiley   +1 more source

Comparison of humoral and cellular immune responses in hematologic diseases following completed vaccination protocol with BBIBP-CorV, or AZD1222, or BNT162b2 vaccines against SARS-CoV-2. [PDF]

open access: yesFront Med (Lausanne), 2023
Szabó E   +12 more
europepmc   +1 more source

Ultrasound‐Triggered Nanocomposite “Lever” Hydrogels with a Full Repair System Accelerates Diabetic Foot Ulcer Repair

open access: yesAdvanced Science, EarlyView.
Ultrasound (US)‐treated nanocomposite ‘lever’ hydrogels reprogrammed wound reactive oxygen species (ROS) levels and promoted wound healing in infected diabetic foot ulcers. Abstract Diabetic foot ulcers (DFUs) are a complex mixture of neuropathy, peripheral arterial disease, and infection, where excessive reactive oxygen species (ROS) exacerbates ...
Yuting Shen   +16 more
wiley   +1 more source

Calpain‐2‐Mediated Endothelial Focal Adhesion Disruption in Thoracic Aortic Dissection

open access: yesAdvanced Science, EarlyView.
The elevated expression of Capn2 in endothelial cells activates focal adhesion signaling by cleaving Talin1 and assembling Itgav, which compromises the integrity of the endothelial barrier and induces vascular inflammation. Inhibition of calpain through both pharmacological and transgenic approaches has effectively suppressed the onset and progression ...
Xiaomei Teng   +10 more
wiley   +1 more source

Immune Response after 2 Doses of BNT162b2 mRNA COVID-19 Vaccinations in Children and Adolescents with Cancer and Hematologic Diseases. [PDF]

open access: yesAsian Pac J Cancer Prev, 2022
Poparn H   +7 more
europepmc   +1 more source

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