Results 141 to 150 of about 479,621 (361)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

The Effect of King Grass Silage on the Nitrogen Balance and Hematological Profile of Ettawa Grade Male Goat [PDF]

, 2012
The aims of this research was to study the nutritional value of ensiled King Grass (Pennisetum purpuphoides) to be applied for goat. Twelve Ettawa grade male (PE), + 10 months old, and with average body weight of 19.45 + 3.03 kg were used to determine ...
S., Sunarso
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Prevalence of Isolated Neutropenia at High Altitude in Southern Saudi Arabia: Does Altitude Affect Leucocyte Count?

International Journal of General Medicine, 2020
Husain Y Alkhaldy,1,2 Zuhier A. Awan,3,4 Ahmed A Abouzaid,4,5 Hossameldin M Elbahaie,4,6 Saeed M Al Amoudi,4 Mohamed Andarawi,7 Shehata F Shehata8,9 1Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia ...
Alkhaldy HY, Awan ZA, Abouzaid AA, Elbahaie HM, Al Amoudi SM, Andarawi M, Shehata SF   +6 more
doaj  

Prevalence of Hematological Changes in HIV/AIDS patients in a Tertiary care Hospital in Chhattisgarh

, 2015
Iosr Journals, Dr Archana Toppo Dr Rajeev Lochan Khare   +1 more
openalex   +1 more source

Pathological, ultrastructural and hematological studies on single and combined effect of dietary supplementation with lauric and benzoic acids on Nile tilapia

, 2023
Abdelaziz Rabea, Iman Ibrahim, Hebatallah A. Mahgoub, Ahmed El-Shaieb   +3 more
openalex   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Itraconazole Oral Solution for Primary Prophylaxis of Fungal Infections in Patients with Hematological Malignancy and Profound Neutropenia: a Randomized, Double-Blind, Double-Placebo, Multicenter Trial Comparing Itraconazole and Amphotericin B

, 2000
J L Harousseau, A. W. Dekker, Aspasia Stamatoullas‐Bastard, Αthanasios Fassas, Werner Linkesch, João Gouveia, R. De Bock, Montserrat Rovira, W. Seifert, H. Joosen, Marc Peeters, K. De Beule   +11 more
openalex   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Augmented Renal Clearance of Vancomycin in Hematologic Malignancy Patients

, 2019
Tomohiro Izumisawa, Tomoyoshi Kaneko, Masakazu Soma, Masahiko Imai, Nobuyuki Wakui, Hideo Hasegawa, Tetsuya Horino, Noriko Takahashi   +7 more
openalex   +2 more sources