Results 11 to 20 of about 276,101 (206)

The role of CD180 in hematological malignancies and inflammatory disorders [PDF]

open access: yes, 2023
Toll-like receptors play a significant role in the innate immune system and are also involved in the pathophysiology of many different diseases. Over the past 35 years, there have been a growing number of publications exploring the role of the orphan ...
Volpi, E.V.   +6 more
core   +1 more source

A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms [PDF]

open access: yes, 2009
Background: Alterations in the DNA methylation pattern are a hallmark of leukemias and lymphomas. However, most epigenetic studies in hematologic neoplasms (HNs) have focused either on the analysis of few candidate genes or many genes and few HN entities,
Christiane Pott   +180 more
core   +2 more sources

Hypercoagulability in hematological malignancies [PDF]

open access: yes, 2015
Patients with cancer are at high risk for venous thrombosis, the undesired formation of blood clots within the veins. Historically, this high risk was mainly attributed to patients with solid tumors, but recent studies have indicated that the risk is at ...
Lauw, M.N.
core   +25 more sources

MRI of bone marrow abnormalities in hematological malignancies [PDF]

open access: yes, 2013
Magnetic resonance imaging (MRI) is essential for evaluating bone marrow. Bone marrow undergoes constant modification and its appearance on MRI changes in response.
Kunihiko Fukuda,   +7 more
core   +1 more source

Trimethoprim-sulfamethoxazole as Pneumocystis jiroveci pneumonia prevention in patients undergoing methotrexate therapy for hematological malignancies: A review of the literature

open access: yes, 2020
Methotrexate is a cytotoxic agent that is commonly used to treat autoimmune diseases, and both solid and hematological malignancies. Drug interactions are of particular concern during methotrexate therapy, as they have the potential to alter the ...
King, LD, Anoopkumar-Dukie, S, Sia, H
core   +1 more source

Emerging metabolic targets in the therapy of hematological malignancies [PDF]

open access: yes, 2013
During the last decade, the development of anticancer therapies has focused on targeting neoplastic-related metabolism. Cancer cells display a variety of changes in their metabolism, which enable them to satisfy the high bioenergetic and biosynthetic ...
Alexandre Arcaro   +5 more
core   +2 more sources

Autophagy in Hematological Malignancies [PDF]

open access: yes, 2022
Autophagy is a highly conserved metabolic pathway via which unwanted intracellular materials, such as unfolded proteins or damaged organelles, are digested.
García, Paloma   +10 more
core   +3 more sources

Immunogenomic Landscape of Hematological Malignancies [PDF]

open access: yes, 2020
Understanding factors that shape the immune landscape across hematological malignancies is essential for immunotherapy development. We integrated over 8,000 transcriptomes and 2,000 samples with multilevel genomics of hematological cancers to investigate
Sirpa Leppä   +49 more
core   +1 more source

Preleukemia: hematological disorders prior to onset of leukemia [PDF]

open access: yes, 1975
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Mikochi, Hiroshi   +5 more
core   +1 more source

Centrosome Defects in Hematological Malignancies: Molecular Mechanisms and Therapeutic Insights

open access: yes, 2022
Defects in centrosomes are associated with a broad spectrum of hematological malignancies, such as leukemia and lymphoma. Centrosomes in these malignancies display both numerical and structural aberrations, including alterations in the number and size of
Mingzheng Hu, Jun Zhou, Yijie Wang
core   +1 more source
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