Results 191 to 200 of about 407,671 (265)

PIEZO1 is Required for Acute Myeloid Leukemia Progression and Leukemia Stem Cell Maintenance via HIF1A‐SLC7A11 Axis‐Mediated Ferroptosis Defense

Advanced Science, EarlyView.
This study identifies the mechanosensor PIEZO1 as a key factor in promoting acute myeloid leukemia progression and uncovers a ferroptosis defense system mediated by PIEZO1‐HIF1A‐SLC7A11 axis that is essential for leukemia stem cell maintenance. This ferroptotic defense system may represent a unique vulnerability for leukemia stem cells, providing a ...
Tiantian Zhang, Ziyan Cao, Kexin Gao, Shuxin Yao, Yanbing Zheng, Manman Cui, Rong Yin, Guoqiang Han, Jin Hu, Chengyi Wang, Haojian Zhang   +10 more
wiley   +1 more source

Long-term MAPK inhibition of childhood refractory-Langerhans cell histiocytosis: an observational study of 288 patients. [PDF]

Blood Adv
Donadieu J, Evseev D, Pegoraro F, Sieni E, Slater O, Hutter C, Astigarraga I, Lehrnbecher T, van den Bos C, Simonin M, Ahlmann M, Barkaoui M, Le Louet S, Chevallier A, Chalard F, Nguyen T, Holzhauer S, Beutel K, Haenicke H, Escherich G, Garcia-Obregon S, Valero-Arrese L, Ruano D, Moreno MA, Habes D, Lacaille F, McLin V, Bomken S, Bishop H, Penn A, Naeije L, Kabbara N, Milne P, Hélias-Rodzewicz Z, Kolenova A, Renard C, Berard PM, Thalhammer J, Pagnier A, Salmon A, Aladjidi N, Olivier L, Saultier P, Blanc L, Gandemer V, Schneider P, Hessissen L, Golan M, Elitzur S, Ben Arush M, Lustig DA, Dvir R, Raciborska A, Malas Z, Diallo S, Levy G, Efremova V, Munthe-Kaas MC, von Bahr Greenwood T, Felizzia G, Braier J, Boudiaf H, Ben Fraj I, Svojgr K, Krenova Z, Bernard F, Adam C, Karaoli E, Kristensen IA, Dahl C, Trambusti I, Gaspari S, De Fusco C, Chiaravalli S, Corti P, Todesco A, Papadakis V, Luz I, Costa V, Osipova D, Lyudovskikh E, Maschan M, Bronin G, Burcev E, Idbaih A, Larabi IA, Bellouard M, Alvarez JC, Novosad O, Collin M, Henter JI, Emile JF, Héritier S, Minkov M.   +93 more
europepmc   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Ropeginterferon alfa-2b-njft treatment in essential thrombocythemia across different driver mutations: results from a North American, single-arm, multicentre study (EXCEED-ET). [PDF]

Lancet Reg Health Am
Reeves BN, El Chaer F, Foltz L, Tashi T, Abu-Zeinah G, Qin A, Lucas J, Halpern AB, Maze D, Safah H, O'Connell CL, Goel S, Rein L, Fang B, How J, Babu S, Li Z, Cerquozzi S, Oh ST, Hunter AM, Podoltsev N, Vachhani P, Cunningham JM, Hillis C, Bose P, Yacoub A, Mascarenhas J, Zagrijtschuk O, Castro H, Mesa RA, Masarova L.   +30 more
europepmc   +1 more source

Hematology in times of crisis: Lessons learned and strategic priorities from the EHA-ASH Joint Workshop on Ukraine. [PDF]

Hemasphere
Istomin O, Yakimkova T, Belkhedim R, Bolaños N, Döhner K, Ganser A, Haferlach T, Ilbawi A, Kacharian A, Kizyma R, Klymenko S, Korenkova S, Leebeek F, Lysytsia O, Medvediev B, Mlynarski W, Niederwieser D, Nogovitsyna Y, Rondelli D, Selina I, Usenko G, Shokun N, Heyman M, Niemeyer C, Müller A.   +24 more
europepmc   +1 more source

Understanding the impact of social determinants of health in hematology: a scoping review of trends across journals and over time. [PDF]

Blood Adv
Lu B, Troyer J, Krause KJ, Lapite A, Aviles M, Della-Moretta S, Dobson D, Farrokhi K, Hasanali ZS, Pillai P, Taborda C, Villagomez L, Vo PT, Wang'ondu RW, Yui JC, Weyand AC, Fingrut WB.   +16 more
europepmc   +1 more source

Allogeneic Stem Cell Transplantation in Patients With Mixed Chimerism Following Double Cord Blood Transplantation: A Case Report. [PDF]

Case Rep Hematol
Park Y, Lee S, Kim J, Kim JA.
europepmc   +1 more source

Antimicrobial use trends in Canadian adult hematology/oncology inpatient wards: a multi-year exploratory analysis from 2018 to 2023. [PDF]

Antimicrob Steward Healthc Epidemiol
Moyana C, Nguyen AK, Conly JM, Thirion DJG, Afra K, Bautista J, Comeau JL, Delport J, Émond Y, Evans GA, Fryters S, Lee BE, Li X, Pasay D, Rajakumar I, Sarhan MA, Slayter K, Tse-Chang A, Varsaneux O, Wong M, Bartoszko JJ.   +20 more
europepmc   +1 more source

Guidelines in hematology.

Haematologica, 2002
Baccarani, M, LO COCO, FRANCESCO, Bacigalupo, A.   +2 more
openaire   +2 more sources

Analysis of infectious complications in paediatric autoimmune neutropenia: a French nationwide retrospective cohort study. [PDF]

Arch Dis Child
Dhersin R, Trebucq E, Rimbert M, Rouger-Gaudichon J, Neumann F, Chastagner P, Guimard G, Plantaz D, Billet S, Abouchahla W, Petit A, Jeziorski E, Li Thiao Te V, Cheikh N, Aladjidi N, Carausu L, Thomas C, Grain A, Benadiba J, Blanc L, Cousin E, Marie-Cardine A, Moshous D, Pasquet M, Lejeune J, Azarnoush S, Beaupain B, Dubée V, Pellier I, Donadieu J, Mallebranche C.   +30 more
europepmc   +1 more source