Results 91 to 100 of about 14,341 (209)

DNA methyltransferases and their roles in tumorigenesis [PDF]

, 2017
DNA methylation plays an important role in gene expression, chromatin stability, and genetic imprinting. In mammals, DNA methylation patterns are written and regulated by DNA methyltransferases (DNMTs), including DNMT1, DNMT3A and DNMT3B. Recent emerging
Jie Xu, Wu Zhang
core   +1 more source

Interior Decorative VOCs Elevate T Cell‐Mediated Obstructive Lung Disease Risks via Osteogenesis‐Driven Lymphoid‐Biased Hematopoiesis

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study utilizes a whole‐body inhalation model to reveal that interior decorative VOCs exposure persistently elevates alveolar T cells. This increase is attributed to lymphoid‐biased hematopoiesis in the bone marrow, which is further driven by IL‐6/IL‐17A‐mediated osteogenic differentiation.
Hongyan Yu, Jingxu Zhang, Qingping Liu, Duxing Li, Ruonan Pan, Gan Miao, Yidi Chen, Zhe Kou, Guangbo Qu, Rong Zhang, Xiaoting Jin, Yuxin Zheng   +11 more
wiley   +1 more source

Common extracellular matrix regulation of myeloid cell activity in the bone marrow and tumor microenvironments [PDF]

, 2017
The complex interaction between cells undergoing transformation and the various stromal and immunological cell components of the tumor microenvironment (TME) crucially influences cancer progression and diversification, as well as endowing clinical and ...
Chiodoni, Claudia, Colombo, Mario P, Sangaletti, Sabina, Tripodo, Claudio   +3 more
core   +1 more source

What Is Your Diagnosis? Splenic Mass in an African Pygmy Hedgehog

Veterinary Clinical Pathology, EarlyView.
Gabriela Hartmann, Milena Carolina Paz, Paola Sônego, Ana Carolina Contri Natal, Lívia Surita, Marcele Bettim Bandinelli, Luciana Sonne   +6 more
wiley   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Volume 78, Issue 1, Page 12-25, January 2026.
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Renal extramedullary hematopoiesis as an epiphenomenon of bone marrow dysfunction in a patient with primary myelofibrosis: A rare case report

Radiology Case Reports
Extramedullary hematopoiesis represents a clinical compensatory condition characterized by the growth of hematopoietic tissue outside the bone marrow.
Corrado Ini’, MD, Pietro Valerio Foti, PhD, Andrea Duminuco, MD, Renato Farina, MD, Mariangela Clemenza, MD, Francesco Tiralongo, MD, Emanuele David, MD, Stefano Palmucci, PhD, Giuseppe Alberto Palumbo, PhD, Antonio Basile, PhD   +9 more
doaj   +1 more source

In vitro differentiation of murine hematopoietic progenitor cells toward the myeloid lineage occurs in response to Staphylococcus aureus and yeast species [PDF]

, 2014
We have studied the effect of inactivated microbial stimuli (Candida albicans, Candida glabrata, Saccharomyces boulardii, and Staphylococcus aureus) on the in vitro differentiation of lineage negative (Lin−) hematopoietic progenitor mouse cells. Purified
Dios, Sara de, Estévez, Miguel Ángel, Gil, María Luisa, Gozalbo, Daniel, Maneu, Victoria, Megías, Javier   +5 more
core   +2 more sources

What's Your Diagnosis? A Case of Extreme Thrombocytosis in a Dog

Veterinary Clinical Pathology, EarlyView.
Stephanie F. Anderson, King Long Hannah Lee, Megan Dietz, Sarah Guess, Laura White, Mara S. Varvil   +5 more
wiley   +1 more source

Daratumumab‐based quadruplet for patients with extramedullary multiple myeloma: Results from the Phase II prospective EMN19 study

HemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT Novel therapies are needed for patients with multiple myeloma (MM) and extramedullary plasmacytomas. The prospective, Phase II EMN19 study assessed the efficacy and safety of daratumumab plus bortezomib, cyclophosphamide, and dexamethasone (DaraVCD) in 40 patients with newly diagnosed MM (NDMM; n = 29) or at first relapse (RMM; n = 11) and ...
Meral Beksac, Tulin Fıratlı Tuglular, Francesca Gay, Roberto Mina, Eirini Katodritou, Ali Unal, Michele Cavo, Guner Hayri Ozsan, Vincent H. J. van der Velden, Berna H. Beverloo, Michael Vermeulen, Mark van Duin, Guldane Cengiz Seval, Omur Gokmen Sevindik, Serena Merante, Kyriaki Manousou, Peter Sonneveld, Elena Zamagni, Evangelos Terpos   +18 more
wiley   +1 more source

Spinal cord compression in b-thalassemia: follow-up after radiotherapy

São Paulo Medical Journal
CONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including b-thalassemia.
Silvana Fahel da Fonseca, Maria Stella Figueiredo, Rodolfo Delfini Cançado, Fernando Nakandakare, Roberto Segreto, José Kerbauy   +5 more
doaj   +1 more source