Results 101 to 110 of about 62,520 (247)
A case of perirenal extramedullary hematopoiesis in a patient with primary myelofibrosis
CEN Case Reports, 2017 Extramedullary hematopoiesis (EMH) is hematopoiesis in organs outside the bone marrow and most frequently occurs in the liver, spleen, and lymph nodes.
K. Imai +5 more
semanticscholar +1 more source
American Journal of Hematology, Volume 100, Issue S4, Page 5-15, June 2025.ABSTRACT With the recent publication of new classification systems of hematopoietic neoplasms, understanding how recognition of disease entities has occurred over time and the subsequent development of formal disease classifications is of importance. This review focuses on the early recognition of myeloid disorders, especially chronic myeloid disorders,
Daniel A. Arber, Attilio Orazi
wiley +1 more source
Extramedullary hematopoiesis: A report of two cases
Experimental and Therapeutic Medicine, 2016 Extramedullary hematopoiesis (EMH) is defined as hematopoiesis occurring in organs outside of the bone marrow. The present report describes two cases of thalassemic patients with paraspinal medullary hematopoiesis and analyzes the clinical manifestations,
Huan-Zhu Zhang +5 more
semanticscholar +1 more source
The disruption of hematopoiesis in tumor progression
Blood Science, 2019 . Human adult hematopoiesis maintains homeostasis by replacing depleted progeny pools and inducing a primary immune response to infectious diseases and tumors.
Xiaofang Wang, Yangqiu Li
doaj +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, Volume 100, Issue S4, Page 30-50, June 2025.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
American Journal of Hematology, Volume 100, Issue S4, Page 16-29, June 2025.ABSTRACT Allogeneic hematopoietic stem‐cell transplantation (HCT) remains the only potentially curative therapy for patients with myelodysplastic neoplasms (MDS) and myelofibrosis (MF) and is the standard care for eligible patients with higher‐risk disease. Despite significant advancements, both diseases pose unique challenges due to their clinical and
Nico Gagelmann, Nicolaus Kröger
wiley +1 more source
Cancer Medicine, Volume 14, Issue 11, June 2025.Tregs levels at diagnosis were assessed to predict early relapse (ER18) and functional high risk in multiple myeloma. Our findings suggest that Tregs at diagnosis could serve as a potential biomarker for early relapse and long‐term prognosis in newly diagnosed patients.
Qiaolin Zhou +9 more
wiley +1 more source
Cancer Medicine, 2016 We investigated noninvasive procedures by hybrid imaging to assess the sites of active or inactive hematopoiesis in patients with primary myelofibrosis (PMF).
M. Ojeda-Uribe +5 more
semanticscholar +1 more source
Spinal cord compression in b-thalassemia: follow-up after radiotherapy
São Paulo Medical JournalCONTEXT: Spinal cord compression due to extramedullary hematopoiesis is a well-described but rare syndrome encountered in several clinical hematologic disorders, including b-thalassemia.
Silvana Fahel da Fonseca +5 more
doaj +1 more source
Cancer, Volume 131, Issue 10, 15 May 2025.The authors compared allogeneic (allo‐SCT) with autologous stem cell transplantation (auto‐SCT) in patients who relapsed after first‐line auto‐SCT. The results showed significantly better progression‐free and overall survival with auto‐SCT. Abstract Background Allogeneic stem cell transplantation (allo‐SCT) has curative potential and was previously ...
Heinz Ludwig +11 more
wiley +1 more source