Results 101 to 110 of about 14,341 (209)
Extramedullary hematopoiesis (EMH) is the development of hematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare, and there are very few case reports concerning the kidney. We describe a case
Basharat Mubeen +4 more
doaj +1 more source
A Lucky Mistake: The Splenic Glands of Marcello Malpighi [PDF]
PURPOSE OF THE REVIEW: More than 50% of all gynaecological cancers can be classified as rare tumours (defined as an annual incidence of
Chaviano, Felicia +3 more
core +1 more source
Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis
Abstract Erythropoiesis is a finely regulated process ensuring continuous red blood cell production to maintain oxygen delivery. Disruptions in this process give rise to defective erythropoiesis, characterized by impaired lineage commitment and progenitor development, and ineffective erythropoiesis (IE), marked by expansion of erythroid progenitors ...
Sara El Hoss +3 more
wiley +1 more source
Marrow adipose tissue expansion coincides with insulin resistance in MAGP1-deficient mice [PDF]
Marrow adipose tissue (MAT) is an endocrine organ with the potential to influence skeletal remodeling and hematopoiesis. Pathologic MAT expansion has been studied in the context of severe metabolic challenge, including caloric restriction, high fat diet ...
Abou-Ezzi, Grazia +8 more
core +3 more sources
ABSTRACT In the AVALON cohort of relapsed/refractory AML treated with venetoclax plus hypomethylating agents, NPM1 and IDH1/2 mutations showed no significant impact on response or survival. These findings indicate that prognostic models for relapsed AML should consider treatment context rather than baseline mutation status.
Calogero Vetro +22 more
wiley +1 more source
Elranatamab Exposure–Safety Analysis in Relapsed or Refractory Multiple Myeloma
Abstract Elranatamab, a bispecific antibody targeting B‐cell maturation antigen, is approved for the treatment of relapsed or refractory multiple myeloma (RRMM). An exposure–safety analysis was conducted using the data from patients with RRMM across four clinical studies, MagnetisMM‐1, 2, 3, and 9 (NCT03269136, NCT04798586, NCT04649359, and NCT05014412)
Pooneh Soltantabar +5 more
wiley +1 more source
Safety of tolfenamic acid in Japanese quails. ABSTRACT Objective This study evaluated the safety profile of tolfenamic acid following repeated oral administration in Japanese quails (Coturnix coturnix japonica) at doses of 2 and 8 mg/kg every 12 h for 7 days. Methods The 42 quails were randomly assigned to three groups. The first group (n = 6) received
Fatih Hatipoglu +6 more
wiley +1 more source
ABSTRACT The ongoing invasion of the zoonotic parasite Angiostrongylus cantonensis threatens humans, other mammals, and birds. In Mallorca, neurological disorders associated with this parasite are increasingly reported in free‐living Algerian hedgehogs, Atelerix algirus, raising public health concerns.
Anna Šipková +7 more
wiley +1 more source
Video-assisted thoracoscopic surgery for intrathoracic extramedullary hematopoiesis
Extramedullary hematopoiesis is a rare cause of an intrathoracic mass in individuals with hemolytic disorders. It can be clinically confused with other tumors of the mediastinum.
Giblin E, Frankel K, Mortman K
doaj
Efficacy of Momelotinib in Myelofibrosis Patients: Results From a Multicenter Study
ABSTRACT Momelotinib, a novel JAK1/2 inhibitor with inhibitory activities on activin A receptor type I, has shown breakthrough clinical efficacy in patients with myelofibrosis (MF) and anemia, a disease‐related manifestation of challenging management. In this retrospective real‐life multicenter Italian study, we investigated the safety and efficacy of ...
Maria Carmen Martorelli +34 more
wiley +1 more source

