Results 31 to 40 of about 14,341 (209)
Background. Extramedullary hematopoiesis is most often seen in reticuloendothelial organs specially spleen, liver, or lymph nodes, and it is rarely seen in lung parenchyma.
Massood Hosseinzadeh +3 more
doaj +1 more source
Introduction Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia.
Tabesh Homayoun +5 more
doaj +1 more source
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis
Conventional chemotherapy for killing cancer cells using cytotoxic drugs suffers from low selectivity, significant toxicity, and a narrow therapeutic index.
Hexiao Zhang +11 more
doaj +1 more source
Studies on reticuloendothelial system and hematopoiesis. II. A study on the morphology and function of erythroblastic islet [PDF]
1. For the purpose to clarify the role of reticuloendothelial cells in the center of erythroblastic islet, the medullary and extramedullary erythropoietic foci in convalescence of phenylhydrazine arternia were observed by light and electron microscopies,
Matsuoka, Kenichi
core +1 more source
Inositol phosphatase SHIP1 is a primary target of miR-155 [PDF]
MicroRNA-155 (miR-155) has emerged as a critical regulator of immune cell development, function, and disease. However, the mechanistic basis for its impact on the hematopoietic system remains largely unresolved.
Baltimore, David +3 more
core +3 more sources
Paravertebral Mass in a Patient with Hemolytic Anemia: Computed Tomographic Findings
Extramedullary hematopoiesis is characterized by the presence of hematopoietic tissue outside of the bone marrow and is typically associated with chronic hemolytic anemias.
Juliana França Carvalho +9 more
doaj +1 more source
Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder [PDF]
Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after injection of bacterial lipopolysaccharide (LPS) correlated ...
Baltimore, David +7 more
core +3 more sources
Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice [PDF]
Juvenile Myelomonocytic Leukemia (JMML) is a pediatric myeloproliferative neoplasm (MPN) that has a poor prognosis. Somatic mutations in Ptpn11 are the most frequent cause of JMML and they commonly occur in utero.
Chan, Rebecca J. +4 more
core +1 more source
Osteopetrosis: a rare case of portal hypertension
Osteopetrosis is a rare genetic bone disorder characterized by a defect in osteoclasts recruitment and function. Its manifestations are numerous and they mainly include skeletal and dental deformities, cranial nerve entrapment and infections.
Amal Khsiba +7 more
doaj +1 more source
From EMT to HSC to AML: ZEB2 is a cell fate switch. [PDF]
In this issue of Blood, complimentary studies by J. Li et al1 and H. Li et al2 identify the transcription factor ZEB2 as a critical regulator of multilineage differentiation in both normal and malignant hematopoiesis.
Meyer, Sara E.
core +2 more sources

