Results 31 to 40 of about 62,520 (247)
Extramedullary hematopoiesis occurs in the setting of hematologic disorders or malignancies when the activity of the bone marrow is insufficient to generate blood cells.
Janet Rae Julson+3 more
doaj
Multi-Agent Systems and Blood Cell Formation [PDF]
The objective of this chapter is to give an insight of the mathematical modellng of hematopoiesis using multi-agent systems. Several questions may arise then: what is hematopoiesis and why is it interesting to study this problem from a mathematical point of view? Has the multi-agent system approach been the only attempt done until now?
arxiv +1 more source
Master regulators as order parameters of gene expression states [PDF]
Cell type-specific gene expression patterns are represented as memory states of a Hopfield neural network model. It is shown that order parameters of this model can be interpreted as concentrations of master transcription regulators that form concurrent positive feedback loops with a large number of downstream regulated genes.
arxiv +1 more source
Background. Extramedullary hematopoiesis is most often seen in reticuloendothelial organs specially spleen, liver, or lymph nodes, and it is rarely seen in lung parenchyma.
Massood Hosseinzadeh+3 more
doaj +1 more source
Introduction Extramedullary hematopoiesis occurs in approximately 15% of cases of thalassemia. Intracranial deposits of extramedullary hematopoiesis are an extremely rare compensatory process in intermediate and severe thalassemia.
Tabesh Homayoun+5 more
doaj +1 more source
MCL-1 Inhibitor S63845 Distinctively Affects Intramedullary and Extramedullary Hematopoiesis
Conventional chemotherapy for killing cancer cells using cytotoxic drugs suffers from low selectivity, significant toxicity, and a narrow therapeutic index.
Hexiao Zhang+11 more
doaj +1 more source
On the existence and exponential attractivity of a unique positive almost periodic solution to an impulsive hematopoiesis model with delays [PDF]
In this paper, a generalized model of hematopoiesis with delays and impulses is considered. By employing the contraction mapping principle and a novel type of impulsive delay inequality, we prove the existence of a unique positive almost periodic solution of the model.
arxiv +1 more source
Extramedullary hematopoiesis in renal allograft [PDF]
Extramedullary hematopoiesis (EMH), defined as the presence of hematopoietic elements outside of the medullary cavity of bone, has been reported in patients with various hematopoietic neoplasms including myelofibrosis. EMH commonly occurs in the liver and spleen (resulting in hepatosplenomegaly) and uncommonly involves the kidney.
Guilan Chen+4 more
openaire +3 more sources
A mathematical study of the hematopoiesis process with applications to chronic myelogenous leukemia [PDF]
This paper is devoted to the analysis of a mathematical model of blood cells production in the bone marrow (hematopoiesis). The model is a system of two age-structured partial differential equations. Integrating these equations over the age, we obtain a system of two nonlinear differential equations with distributed time delay corresponding to the cell
arxiv +1 more source
Paravertebral Mass in a Patient with Hemolytic Anemia: Computed Tomographic Findings
Extramedullary hematopoiesis is characterized by the presence of hematopoietic tissue outside of the bone marrow and is typically associated with chronic hemolytic anemias.
Juliana França Carvalho+9 more
doaj +1 more source