Results 81 to 90 of about 62,520 (247)
Extramedullary hematopoiesis in leiomyoma uteri
Journal of the Turkish German Gynecological Association, 2011 Extramedullary hematopoiesis (EMH) that often occurs as a compensatory reaction to an underlying hematologic abnormality is a non-neoplastic proliferation of hematopoietic tissue outside the bone marrow and peripheral blood. Rarely, EMH may be seen in hematologically normal individuals. EMH is most commonly (95%) seen in reticuloendothelial organs such
Abdullah Aydin +4 more
openaire +3 more sources
Existence and multiplicity of periodic solutions for a hematopoiesis model [PDF]
arXiv, 2015 A general nonautonomous Mackey-Glass equation for the regulation of the hematopoiesis with several non-constant delays is studied. Using topological degree methods, we prove the existence and multiplicity of positive periodic solutions.
arxiv
Optimal Experimental Design for Mathematical Models of Hematopoiesis [PDF]
arXiv, 2020 The hematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells. Feedback regulation is crucial to tightly control this system, but the specific mechanisms by which control is exerted are not completely understood.
arxiv
The role of blinatumomab in adult acute B lymphoblastic leukaemia
British Journal of Haematology, EarlyView.Blinatumomab, a CD19‐directed bispecific T‐cell engager, has become a crucial part of BCP‐ALL therapy in r/r disease, MRD‐positive disease and has recently been implemented into first‐line therapy of BCP‐ALL. This review discusses important clinical trials with a focus on blinatumomab in first‐line therapy of adult BCP‐ALL.
Anne C. Wilke, Nicola Gökbuget
wiley +1 more source
Thalassemia ReportsExtramedullary hematopoiesis (EMH) serves as a compensatory mechanism in chronic hemolytic anemias, such as thalassemia, and can result in spinal cord compression.
Konstantinos Manganas +4 more
doaj +1 more source
Thalassemia, extramedullary hematopoiesis, and spinal cord compression: A case report
Surgical neurology international, 2016 Background: Extramedullary hematopoiesis (EMH) refers to hematopoiesis outside of the medulla of the bone. Chronic anemia states such as thalassemia can cause hematopoietic tissue to expand in certain locations.
Syed Sarmad Bukhari +2 more
semanticscholar +1 more source
Hematopoietic cancers and Nup98 fusions: determining common mechanisms of malignancy [PDF]
, 2012 Chromosomal aberrations are very frequent in leukemias and several recurring mutations capable of malignant transformation have been described. These mutations usually occur in hematopoietic stem cells (HSC), transforming them into leukemia stem cells.
arxiv +1 more source
Sparsity in Continuous-Depth Neural Networks [PDF]
arXiv, 2022 Neural Ordinary Differential Equations (NODEs) have proven successful in learning dynamical systems in terms of accurately recovering the observed trajectories. While different types of sparsity have been proposed to improve robustness, the generalization properties of NODEs for dynamical systems beyond the observed data are underexplored.
arxiv
Organoids in Haematologic Research: Advances and Future Directions
Cell Proliferation, EarlyView.This review focuses on the advancements in organoid technology and its transformative role in haematological research, particularly in the modelling of haematopoietic tissues, blood diseases and drug development. It also offers an outlook on the future prospects of organoids in personalised medicine and the study of disease mechanisms.
Liangzheng Chang +4 more
wiley +1 more source
Stem Cell Research & Therapy, 2020 Purpose Selected placental mesenchymal stromal cells isolated from the fetal mesenchymal placental tissues (f-hPSCs) were tested as cell therapy of lethal acute radiation syndrome (ARS) with bone marrow regeneration and induced extramedullary ...
Evgenia Volinsky +6 more
doaj +1 more source