Results 1 to 10 of about 67,362 (119)

Clinical Relevance of ABCB1, ABCG2, and ABCC2 Gene Polymorphisms in Chronic Myeloid Leukemia Patients Treated With Nilotinib

Frontiers in Oncology, 2021
Tyrosine kinase inhibitors (TKIs) have radically changed the outcome of chronic myeloid leukemia (CML) patients in the last 20 years. Moreover, the advent of second generation TKIs, namely nilotinib and dasatinib, have largely increased the number of CML
Federica Loscocco, Giuseppe Visani, Annamaria Ruzzo, Irene Bagaloni, Fabio Fuligni, Sara Galimberti, Antonello Di Paolo, Fabio Stagno, Patrizia Pregno, Mario Annunziata, Antonella Gozzini, Sara Barulli, Elisa Gabucci, Mauro Magnani, Alessandro Isidori   +14 more
doaj   +1 more source

Influence of gut microbiome on multiple myeloma: friend or foe?

Journal for ImmunoTherapy of Cancer, 2020
Multiple myeloma (MM) is a malignancy of terminally differentiated plasma cells, which typically evolves over time from its precursor, monoclonal gammopathy of undetermined significance.
Marcos de Lima, Nausheen Ahmed, Mahmoud Ghannoum, Molly Gallogly, Ehsan Malek   +4 more
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Successful treatment of pulmonary hypertension following hematopoietic stem cell transplant with a single oral tadalafil: a case report

Pulmonary Circulation, 2021
A 46‐year‐old man who had undergone hematopoietic stem cell transplant twice because of acute lymphoblastic leukemia with recurrence presented with dyspnea, leading to a diagnosis of pulmonary arterial hypertension which was quickly and effectively ...
Toshikazu D. Tanaka, David C. Ishizawar, Takeshi Saito, Akira Yoshii, Michihiro Yoshimura   +4 more
doaj   +1 more source

Brazilian Nutritional Consensus in Hematopoietic Stem Cell Transplantation: Adults

Einstein (São Paulo), 2020
The nutritional status of patients submitted to hematopoietic stem cell transplant is considered an independent risk factor, which may influence on quality of life and tolerance to the proposed treatment.
Juliana Bernardo Barban, Belinda Pinto Simões, Bruna Del Guerra de Carvalho Moraes, Cássia Rehem da Anunciação, Cristiane Santos da Rocha, Daniela Cristina Querino Pintor, Daiane Cristina Guerra, Deise Andrade Silva, Edith de Castro Martins Brandão, Fábio Kerbauy, Fernanda Ramos de Oliveira Pires, Graciele Lima Morais, Jayr Schmidt Filho, Juliana Maria Faccioli Sicchieri, Karine Sampaio Nunes Barroso, Luciana Verçoza Viana, Mariana Hollanda Martins da Rocha, Maysa Penteado Guimarães, Natalia Leonetti Couto Lazzari, Nelson Hamerschlak, Patricia Ramos, Plinio Nascimento Gomes, Priscila da Silva Mendonça, Raquel Candido de Oliveira, Renata Corrêa Scomparim, Ricardo Chiattone, Rosa Wanda Diez-Garcia, Thaís de Campos Cardenas, Thais Manfrinato Miola, Thalita Cristina de Mello Costa, Vanderson Rocha, Andrea Z Pereira   +31 more
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Intramuscular Injection of Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis Patients: A Randomized Clinical Trial

Frontiers in Neuroscience, 2020
BackgroundPreclinical studies suggest that stem cells may be a valuable therapeutic tool in amyotrophic lateral sclerosis (ALS). As it has been demonstrated that there are molecular changes at the end-plate during the early stages of motorneuron ...
Emilio Geijo-Barrientos, Carlos Pastore-Olmedo, Carlos Pastore-Olmedo, Pedro De Mingo, Miguel Blanquer, Miguel Blanquer, Joaquín Gómez Espuch, Francisca Iniesta, Francisca Iniesta, Natalia García Iniesta, Natalia García Iniesta, Ana García-Hernández, Ana García-Hernández, Carlos Martín-Estefanía, Laura Barrios, José M. Moraleda, José M. Moraleda, Salvador Martínez, Salvador Martínez   +18 more
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Fungal infections in hematopoietic stem-cell transplant patients: a review of epidemiology, diagnosis, and management

Therapeutic Advances in Infectious Disease, 2021
The advent of bone marrow transplant has opened doors to a different approach and offered a new treatment modality for various hematopoietic stem-cell-related disorders.
Mandeep Singh Rahi, Vishal Jindal, Prachi Pednekar, Jay Parekh, Kulothungan Gunasekaran, Sorabh Sharma, Michael Stender, Ishmael A. Jaiyesimi   +7 more
doaj   +1 more source

Caring for AML Patients During the COVID-19 Crisis: An American and Italian Experience

Frontiers in Oncology, 2020
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the subsequent pandemic have impacted every aspect of oncology care worldwide.
Lindsay Wilde, Alessandro Isidori, Gina Keiffer, Neil Palmisiano, Margaret Kasner   +4 more
doaj   +1 more source

Adding hydroxyurea in combination with ruxolitinib improves clinical responses in hyperproliferative forms of myelofibrosis

Cancer Medicine, 2019
Ruxolitinib, an orally bioavailable and selective inhibitor of Janus kinase 1 (JAK1) and JAK2, significantly reduces splenomegaly and disease‐related symptoms in patients with myelofibrosis (MF).
Novella Pugliese, Claudia Giordano, Davide Nappi, Luigiana Luciano, Claudio Cerchione, Mario Annunziata, Beniamino Casale, Elena Crisà, Maria Rosaria Villa, Luca Pezzullo, Maria Iovine, Marco Picardi, Francesco Grimaldi, Fabrizio Pane, Vincenzo Martinelli   +14 more
doaj   +1 more source

Methotrexate-Induced Acute Leukemia: Report of Three Cases and Review of the Literature

Clinical Medicine Insights: Case Reports, 2009
For many years, methotrexate has been used in the treatment of certain chronic medical disorders e.g. rheumatoid arthritis and psoriasis as well as a number of malignant disorders e.g.
Khalid A. Al-Anazi, Khalid I. Eltayeb, Mohammed Bakr, Fahad I. Al-Mohareb   +3 more
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Endocrinopathies after Allogeneic and Autologous Transplantation of Hematopoietic Stem Cells

The Scientific World Journal, 2014
Early and late endocrine disorders are among the most common complications in survivors after hematopoietic allogeneic- (allo-) and autologous- (auto-) stem cell transplant (HSCT).
Francesco Orio, Giovanna Muscogiuri, Stefano Palomba, Bianca Serio, Mariarosaria Sessa, Valentina Giudice, Idalucia Ferrara, Libuse Tauchmanovà, Annamaria Colao, Carmine Selleri   +9 more
doaj   +1 more source