Results 171 to 180 of about 6,010,235 (261)

Metrnl: A Novel Therapeutic Target in Atherosclerosis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Atherosclerosis is a chronic inflammatory vascular disease and the main pathological basis of cardiovascular and cerebrovascular events. Exploration of endogenous protective factors in the disease is beneficial for the establishment of new therapeutic strategies.
Pin Wang, Dao‐Xin Wang, Chao‐Yu Miao
wiley   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

open access: yesiNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li   +11 more
wiley   +1 more source

Lipid dysregulation after hematopoietic stem cell transplant. [PDF]

open access: yesHaematologica
Koo J   +13 more
europepmc   +1 more source

Exploring vaginal microbiota–tissue resident stem cell crosstalk: VCAM1/Akt signaling ‐mediated enhancement of regenerative capacity

open access: yesInterdisciplinary Medicine, EarlyView.
Vaginal microbiota‐derived secretory factors enhance the regenerative capacity of human endometrial stem cells by upregulating VCAM1 and activating PI3K/Akt signaling. This microbiota–stem cell crosstalk promotes self‐renewal, migration, multilineage differentiation, and metabolic reprogramming in vitro and in vivo, establishing a novel microbiota ...
Soo‐Rim Kim   +6 more
wiley   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia   +6 more
wiley   +1 more source

Pregnancy after hematopoietic stem cell transplant: an international multicenter study. [PDF]

open access: yesBlood Adv
Salooja N   +22 more
europepmc   +1 more source

MRI Proton Density Fat Fraction as a Biomarker of Marrow Recovery Following Organ‐Sparing Total Marrow Irradiation in Sickle Cell Disease

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Noninvasive quantitative assessment of marrow recovery after curative therapies such as total marrow irradiation (TMI) and bone marrow transplantation (BMT) remain poorly defined, particularly in sickle cell disease (SCD). Purpose To evaluate MRI‐derived proton density fat fraction (PDFF) as a biomarker of marrow recovery following ...
Malakeh Malekzadeh   +12 more
wiley   +1 more source

Technique considerations for implementing volumetric‐modulated arc therapy for total body irradiation within an Australian tertiary institution

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 165-172, March 2025.
In 2020, our institution transitioned to the Eclipse™ treatment planning system and to Truebeam® linear accelerators with 6 MV and 10 MV energies. The linear accelerators were installed in smaller bunkers that could not accommodate 400 cm FAD. A multidisciplinary team within the institution was created to evaluate existing total body irradiation ...
Gabriella La Macchia   +5 more
wiley   +1 more source

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