Results 111 to 120 of about 461,308 (260)

Phorbol ester induced ex vivo expansion of rigorously-defined phenotypic but not functional human cord blood hematopoietic stem cells: a cautionary tale demonstrating that phenotype does not always recapitulate stem cell function [PDF]

, 2019
Broxmeyer, Hal E., Chen, Yandan, Guo, Bin, Huang, Xinxin, Jiang, Rongzhen, Liu, Sheng, Teng, Yincheng, Wan, Jun, Yao, Chunxu   +8 more
core   +1 more source

Allogeneic hematopoietic stem cell transplantation for MDS and CMML: recommendations from an international expert panel.

Blood, 2017
T. D. Witte, D. Bowen, M. Robin, L. Malcovati, D. Niederwieser, I. Yakoub-Agha, G. Mufti, P. Fenaux, G. Sanz, R. Martino, E. Alessandrino, F. Onida, A. Symeonidis, J. Passweg, G. Kobbe, A. Ganser, U. Platzbecker, J. Finke, M. Gelder, A. A. Loosdrecht, P. Ljungman, R. Stauder, L. Volin, H. Deeg, C. Cutler, W. Saber, R. Champlin, S. Giralt, C. Anasetti, N. Kröger   +29 more
semanticscholar   +1 more source

The INSPECTOR study: enhanced feasibility for clinical translation of a multi‐cancer early detection method based on enzyme‐assisted high signal‐to‐noise ratio sequencing of methylated circulating tumor DNA

Cancer Communications, EarlyView.
Abstract Background Blood‐based cell‐free DNA (cfDNA) methylation testing has emerged as a promising approach for multi‐cancer early detection (MCED), holding the potential to improve cancer survival rates. However, traditional bisulfite‐based methods often encounter sensitivity limitations in detecting early‐stage malignancies or certain cancer types.
Hui‐Yan Luo, Wei Wei, Pansong Li, Qi‐Hua Zhang, Zhipeng Zhou, Liang Cui, Yong‐Bin Lin, Hong Yang, Xianyu Zhong, Qingfeng Liu, Han Yang, Kong‐Jia Luo, Hai‐Bo Qiu, Shu‐Qiang Yuan, Yuan‐Fang Li, Zhi‐Wei Zhou, Xiao‐Jun Lin, Bo‐Kang Cui, Rong‐Xin Zhang, Wen‐Hua Fan, He Huang, Chun‐Yan Lan, Jun‐Dong Li, Zhi‐Qiang Wang, Bin‐Kui Li, Rong‐Ping Guo, Jun Tang, Xin Huang, Mian Xi, Yuying Liu, Chuanbo Xie, Shi Chen, Zhi‐Hu Li, Yu‐Hua Liu, Xiao‐Ting Zhang, Qiang Zeng, Xin Yi, Rui‐Hua Xu   +37 more
wiley   +1 more source

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice

Science Translational Medicine, 2016
Y. Shono, Melissa Docampo, J. Peled, S. M. Perobelli, E. Velardi, J. Tsai, Ann E. Slingerland, O. Smith, L. Young, J. Gupta, Sophia R Lieberman, Hillary V. Jay, Katya Ahr, Kori A. Porosnicu Rodriguez, Ke Xu, Marco Calarfiore, Hendrik Poeck, S. Caballero, S. Devlin, Franck Rapaport, J. Dudakov, A. Hanash, B. Gyurkocza, G. Murphy, C. Gomes, Chen Liu, Eli Moss, S. Falconer, A. Bhatt, Y. Taur, E. Pamer, M. V. D. van den Brink, R. Jenq   +32 more
semanticscholar   +1 more source

The Potential of Phytochemicals to Overcome Multidrug Resistance in Metastatic Melanoma

Chemistry &Biodiversity, EarlyView.
ABSTRACT Metastatic melanoma is the most lethal form of skin cancer, accounting for most skin cancer‐related deaths. Immunotherapies and targeted therapies have improved overall and progression‐free survival rates in metastatic melanoma patients. The effectiveness of these therapies decreases due to multidrug resistance (MDR).
Jacqueline Maphutha, Danielle Twilley, Mona Dawood, Thomas Efferth, Namrita Lall   +4 more
wiley   +1 more source

Effect of Inpatient Palliative Care on Quality of Life 2 Weeks After Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2016
A. El-Jawahri, T. Leblanc, Harry Vandusen, L. Traeger, J. Greer, W. Pirl, V. Jackson, Jason Telles, Alison M. Rhodes, T. Spitzer, S. Mcafee, Yi-Bin Chen, Stephanie S Lee, J. Temel   +13 more
semanticscholar   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

Clinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich, Meenakshi Srinivasan, Yu Liu Ho, Sandra A.G. Visser, Geraldine Ferron‐Brady, Georgios Vlasakakis   +5 more
wiley   +1 more source

Cystatin C‐based eGFR better predicts renal vancomycin clearance than creatinine‐based eGFR in patients with allogeneic stem cell transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Knowledge of the glomerular filtration rate (GFR) is mandatory when dosing renally eliminated drugs such as vancomycin. In clinical practice, different biomarkers and various equations are used to estimate GFR (eGFR), resulting in varying estimates.
Eva‐Maria A. Wansing, Sebastian G. Wicha, Peter Bannas, Alexander Heitkamp, Adrin Dadkhah, Nicolaus M. Kröger, Isabel Molwitz, Claudia Langebrake   +7 more
wiley   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.

Blood, 2014
Y. Taur, R. Jenq, M. Perales, E. Littmann, S. Morjaria, Lilan Ling, Daniel No, Asia Gobourne, A. Viale, P. Dahi, D. Ponce, J. Barker, S. Giralt, M. V. D. van den Brink, E. Pamer   +14 more
semanticscholar   +1 more source