Results 141 to 150 of about 382,649 (338)

Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study

open access: yesCancer Communications, EarlyView.
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen   +46 more
wiley   +1 more source

A Poly (β‐Amino Esters)‐Based Multicomponent Nanoparticle for Efficient mRNA Delivery to Acute Myeloid Leukemia Cells

open access: yesChemistryEurope, EarlyView.
A structurally engineered nonviral vector (poly (β‐amino esters)‐lipid‐palmitic anhydride nanoparticles) integrates a poly(β‐amino ester) core for mRNA binding, palmitic anhydride for enhancing cellular uptake, and cationic 1,2‐Dioleoyl‐3‐trimethylammonium‐propane lipid for endosomal disruption is developed, which achieves 64.4% transfection efficiency
Zheng Wang   +8 more
wiley   +1 more source

A special report: histocompatibility testing guidelines for hematopoietic stem cell transplantation using volunteer donors

open access: hybrid, 1999
Carolyn Katovich Hurley   +12 more
openalex   +1 more source

Bone density loss after allogeneic hematopoietic stem cell transplantation: A prospective study [PDF]

open access: hybrid, 2001
Jean M. Stern   +6 more
openalex   +1 more source

Exposure‐Response Relationships for Axatilimab in Patients with Chronic Graft‐Versus‐Host Disease

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Axatilimab, a high‐affinity humanized monoclonal antibody that targets colony‐stimulating factor 1 receptor, is approved for the treatment of chronic graft‐versus‐host disease (cGVHD). Here, we describe the exposure‐response relationships for efficacy and safety in patients with cGVHD who received axatilimab.
Yan‐ou Yang   +7 more
wiley   +1 more source

Model‐Informed Precision Dosing of Busulfan for Children and Adults Undergoing Allogeneic Hematopoietic Stem Cell Transplantation: A Critical Evaluation of Current PK Models and Dose Recommendations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Busulfan is administered intravenously in conditioning regimens prior to allogeneic hematopoietic stem cell transplantation (HSCT), with model‐informed precision dosing (MIPD) targeting a 4‐day cumulative AUC of 80–100 mg*hour/L. Three pharmacokinetic (PK) models—Bognar, Langenhorst, and McCune—were evaluated using data with a minimum of 1 and a median
Rashudy F. Mahomedradja   +13 more
wiley   +1 more source

Prediction model for EBV infection following HLA haploidentical matched hematopoietic stem cell transplantation

open access: yesJournal of Translational Medicine
Aims Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective treatment for hematological malignancies. However, viral infections, particularly EBV infection, frequently occur following allo-HSCT and can result in multi-tissue and ...
Xun-Hong Cao   +6 more
doaj   +1 more source

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