Annals of Neurology, EarlyView.Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro +16 more
wiley +1 more source
Scientific ReportsMultiple myeloma (MM) is a distinguished hematologic malignancy, with existing studies elucidating its interaction with neutrophil extracellular traps (NETs), which may potentially facilitate tumor growth. However, systematic investigations into the role
Zhijia Zhao +6 more
doaj +1 more source
Design Principle of Gene Expression Used by Human Stem Cells; Implication for Pluripotency [PDF]
arXiv, 2004 Human embryonic stem cells (ESC) are undifferentiated and are endowed with the capacities of self renewal and pluripotential differentiation. Adult stem cells renew their own tissue, but whether they can trans-differentiate to other tissues is still controversial.
arxiv
Nature Communications, 2019 Hematopoietic stem cell transplantation (HSCT) is a curative therapy for blood and immune diseases with potential for many settings beyond current standard-of-care.
A. Czechowicz +15 more
semanticscholar +1 more source
Donor hematopoietic progenitor cells in nonmyeloablated rat recipients of allogeneic bone marrow and liver grafts [PDF]
, 1999 Background. Although the persistence of multilineage microchimerism in recipients of long-surviving organ transplants implies engraftment of migratory pluripotent donor stem cells, the ultimate localization in the recipient of these cells has not been ...
Demetris, AJ +5 more
core +1 more source
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
Annals of Neurology, EarlyView.Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical, and genetic disease mechanisms with a resulting emphasis on ...
Brent L. Fogel +10 more
wiley +1 more source
Three potential sources of cell injuries of lymphoid cells associated with developments of lymphoid leukemia and lymphoma [PDF]
arXiv, 2018 Lymphoid leukemia (LL) and lymphoma are blood cancers developed from lymphoid cells (LCs). To understand the cause and the mechanism of cell transformation of a LC, we studied the potential sources of cell injuries of LCs and analyzed how DNA changes are generated and accumulate in LCs. I.
arxiv
Autologous peripheral hematopoietic stem cell transplantation restores hematopoietic function following marrow ablative therapy [PDF]
, 1988 Anne Kessinger +4 more
openalex +1 more source
Effect in supralethally irradiated rats of granulocyte colony- stimulating factor and lisofylline on hematopoietic reconstitution by syngeneic bone marrow or whole organ passenger leukocytes [PDF]
, 1997 We have previously shown the existence of migratory hematopoietic stem cells in adult solid organs. This study demonstrates that granulocyte colony- stimulating factor (G-CSF) and lisofylline, a phosphatidic acid inhibitor that suppresses hematopoiesis ...
Abdul Rao +23 more
core +1 more source
Hematopoietic stem cell transplantation in Algeria
Hematology/Oncology and Stem Cell Therapy, 2017 Introduction: Algeria is a country of 40.4 million inhabitants and half of which is under 30 years. In Algeria, Health-care insurance covered, 90% of the population. Health care is free and it is supported by the Ministry of Health.
R. Bouhass +8 more
openaire +2 more sources