Results 161 to 170 of about 295,255 (358)

Aminated graphene nanosheet stimulates the maturation of hiPSCs‐derived cardiomyocytes in vitro and enhances their survival in vivo

open access: yesBMEMat, EarlyView.
Aminated graphene (G‐NH2) niche matrix plays a pivotal role in precisely manipulating cardiac differentiation and maturation of hiPSCs. The molecular mechanism underlying cardiomyocyte maturation is closely linked to the PDGF‐β signaling pathway. Cardiomyocytes derived from the G‐NH2 matrix exhibit enhanced activity and functionality in vivo.
Yin Xu   +6 more
wiley   +1 more source

Hematopoietic Stem Cell Transplantation

open access: yesQatar Medical Journal, 2007
About 30 years ago bone marrow transplantation was an experimental procedure carried out as a last resort in terminally ill patients. Nowadays hematopoietic stem cell transplantation (HSCT) has become a standard procedure for many severe malignant or non-malignant disorders of the hematopoietic system.
openaire   +2 more sources

Extranodal diffuse large B‐cell lymphoma: Clinical and molecular insights with survival outcomes from the multicenter EXPECT study

open access: yesCancer Communications, EarlyView.
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen   +46 more
wiley   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

open access: yesChronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok   +5 more
wiley   +1 more source

Ridge, lasso, and elastic-net estimations of the modified Poisson and least-squares regressions for binary outcome data [PDF]

open access: yesarXiv
Logistic regression is a standard method in multivariate analysis for binary outcome data in epidemiological and clinical studies; however, the resultant odds-ratio estimates fail to provide directly interpretable effect measures. The modified Poisson and least-squares regressions are alternative standard methods that can provide risk-ratio and risk ...
arxiv  

Discovery of Novel Pyrido[2,3‐b]Pyrazine Human Cytomegalovirus Polymerase Inhibitors with Broad Spectrum Antiherpetic Activity and Reduced hERG Inhibition

open access: yesChemMedChem, Volume 20, Issue 6, March 15, 2025.
We designed and synthesized a small library of novel non‐nucleoside, polymerase inhibitors of herpesviruses with a pyrido[2,3‐b]pyrazines core. Compound 27, a representative of the library, were identified with reduced hERG inhibition, and broad spectrum antiherpetic activity.
Bing Bai   +6 more
wiley   +1 more source

Clinical manifestations, prognostic factors, and outcomes of adenovirus pneumonia after allogeneic hematopoietic stem cell transplantation

open access: yesVirology Journal
Background Severe pneumonia is one of the most important causes of mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Adenovirus (ADV) is a significant cause of severe viral pneumonia after allo-HSCT, and we aimed to identify
Yuewen Wang   +12 more
doaj   +1 more source

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