Results 161 to 170 of about 264,627 (269)

Clinical manifestations, prognostic factors, and outcomes of adenovirus pneumonia after allogeneic hematopoietic stem cell transplantation

Virology Journal
Background Severe pneumonia is one of the most important causes of mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Adenovirus (ADV) is a significant cause of severe viral pneumonia after allo-HSCT, and we aimed to identify
Yuewen Wang, Xiaohui Zhang, Lanping Xu, Yu Wang, Chenhua Yan, Huan Chen, Yuhong Chen, Fangfang Wei, Wei Han, Fengrong Wang, Jingzhi Wang, Xiaojun Huang, Xiaodong Mo   +12 more
doaj   +1 more source

An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation. [PDF]

, 2019
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility.
Deruaz, Maud, Kerr, Matthew D, Mao, Angelo S, Mooney, David J, Raimondo, Theresa M, Scadden, David T, Shah, Nisarg J, Sharda, Azeem, Shih, Ting-Yu, Tager, Andrew M, Vrbanac, Vladimir D, Weaver, James C   +11 more
core   +1 more source

Stem cell heterogeneity and clonal dynamics explored by PolyloxExpress RNA barcoding [PDF]

All blood and immune cells share the same developmental origin but have diverse functions. Hematopoietic stem cells play a central role in hematopoiesis, as reflected by their ability of multilineage reconstitution of lethally irradiated mice.
Shang, Fuwei
core   +1 more source

Future directions in haploidentical hematopoietic stem cell transplantation

Hematology
Outcomes of haploidentical hematopoietic stem cell transplantation (haplo-SCT) have improved over time. Graft failure and graft-versus-host disease (GVHD), which were important complications in major human leukocyte antigen (HLA)-disparity stem cell ...
Pongthep Vittayawacharin, Piyanuch Kongtim, Stefan O. Ciurea   +2 more
doaj   +1 more source

Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]

, 2012
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Hideyuki Okano, Kazuo Tsubota, Sadafumi Suzuki, Saori Yaguchi, Satoru Morikawa, Shigeto Shimmura, Shinichiro Okamoto, Takaaki Inaba, Tomonori Yaguchi, Yo Mabuchi, Yoko Ogawa, Yumi Matsuzaki, Yutaka Kawakami   +12 more
core   +1 more source

Contemporary Perspectives on Chronic Renal Disorders

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok, Poornima Ajay Manjrekar, Bhushan C. Shetty, Sujina S. S, Rukmini Mysore Srikantiah, Sowndarya Kollampare   +5 more
wiley   +1 more source

Immunologic responses to the third and fourth doses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in cell therapy recipients: a systematic review and meta-analysis

Virology Journal
Background Multiple studies have provided evidence of suboptimal or poor immune responses to SARS-CoV-2 vaccines in recipients of hematopoietic stem cell transplantation (HSCT) and chimeric antigen receptor-T (CAR-T) cell therapy compared to healthy ...
Leyla Sharifi Aliabadi, Mojtaba Azari, Mohammad Reza Taherian, Maryam Barkhordar, Syed Aon Mehdi Abbas, Morteza Azari, Mohammad Ahmadvand, Zahra Salehi, Shiva Rouzbahani, Mohammad Vaezi   +9 more
doaj   +1 more source

Differentiating reactive and neoplastic gamma‐delta (γδ) T‐cell expansions in the peripheral blood and bone marrow

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract The clinical and immunophenotypic attributes of reactive γδ T‐cell expansions are less well characterized than their malignant counterparts, which can pose diagnostic challenges. This study aims to investigate the characteristics and long‐term clinical outcomes of reactive γδ T‐cell expansions.
Hamza Tariq, Zubair Ilyas, Lucy Fu, Yijie Liu, Qing Ching Chen, Kristy Wolniak, Yi‐Hua Chen   +6 more
wiley   +1 more source

Longitudinal monitoring of class‐switched memory‐B cell proportions identifies plausible germinal center failure in patients with suspected immune disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract A reduced proportion of peripheral class‐switched memory B cells (CSM‐B cells) is presumed to indicate ineffective germinal activity. The extent that this finding corresponds to a plausible germinal center failure pathophysiology in patients not diagnosed with CVID or hyper IgM syndrome is not known.
Vijaya Knight, Olivia Starich, Cullen M. Dutmer, Jordan K. Abbott   +3 more
wiley   +1 more source

Hematopoietic stem cell transplantation

Stem Cells and Cloning: Advances and Applications, 2010
Eleftheria Hatzimichael1, Mark Tuthill21Department of Haematology, Medical School of Ioannina, University of Ioannina, Ioannina, Greece; 2Department of Medical Oncology, Hammersmith Hospital, Imperial College National Health Service Trust, London ...
Eleftheria Hatzimichael, Mark Tuthill
doaj