Results 11 to 20 of about 6,174,751 (218)

One novel ACOT7–NPHP4 fusion gene identified in one patient with acute lymphoblastic leukemia: a case report

BMC Medical Genomics, 2022
Background Acute lymphoblastic leukemia (ALL) is a type of heterogeneous hematopoietic malignancy that accounts for approximately 20% of adult ALL. Although ALL complete remission (CR) rate has increased to 85–90% after induction chemotherapy, 40–50% of ...
Xin Zong, Zhijie Kang, Dan Huang, Xuehong Zhang, Yuan Gao, Haina Wang, Weiling Li, Jinsong Yan   +7 more
doaj   +1 more source

Real-world experience of treatment with thrombopoietin receptor agonists in anti-thymocyte globulin-naïve patients with aplastic anemia: an observational retrospective analysis in a single institution

Hematology, 2022
Objective To explore the efficacy and safety of thrombopoietin receptor agonists (TPO-RAs) without anti-thymocyte globulin (ATG) in ATG-naïve patients with aplastic anemia (AA) in a real-world setting.Methods We retrospectively evaluated treatment ...
Masaki Iino, Atsushi Jinguji, Tomoya Sato, Ayato Nakadate   +3 more
doaj   +1 more source

Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]

Cytotherapy, 2009
Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo, Battiwalla, Peiman, Hematti
openaire   +2 more sources

Hematopoietic stem cell transplantation in Egypt [PDF]

Bone Marrow Transplantation, 2008
Hematopoietic SCT is now an established treatment modality with definitive indications for many hematological disorders. However, this line of treatment requires tremendous resources, and it becomes increasingly difficult for transplanters practicing in the developing world to reconcile the difference between what is possible and what is available.
Hk, Mahmoud, Am, El-Haddad, Oa, Fahmy, M, El-Emary, A, Nassar, M, Abdel-Mooti, A, Sobhy, A, Sultan   +7 more
openaire   +2 more sources

Identification of a novel HOOK3-FGFR1 fusion gene involved in activation of the NF-kappaB pathway

Cancer Cell International, 2022
Background Rearrangements involving the fibroblast growth factor receptor 1 (FGFR1) gene result in 8p11 myeloproliferative syndrome (EMS), which is a rare and aggressive hematological malignancy that is often initially diagnosed as myelodysplastic ...
Xuehong Zhang, Furong Wang, Fanzhi Yan, Dan Huang, Haina Wang, Beibei Gao, Yuan Gao, Zhijie Hou, Jiacheng Lou, Weiling Li, Jinsong Yan   +10 more
doaj   +1 more source

Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation: a global observational study [PDF]

, 2013
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro, Horowitz, Mary, Passweg, Jakob, Bouzas, Luis Fernando, Szer, Jeff, Niederwieser, Dietger, Gratwohl, Alois, Aljurf, Mahmoud, Iida, Minako, Kodera, Yoshihisa, Pasquini, Marcelo C., Marrow Transplantation,, Lipton, Jeff, Worldwide Network of Blood,, Gratwohl, Michael, Baldomero, Helen, Frauendorfer, Karl, Baldomero H, Niederwieser D, Horowitz M, Lipton J, Szer J, Kodera Y, Gratwohl M, Gratwohl A, Aljurf M, Iida M, Passweg J, Pasquini MC, Madrigal A, Bouzas LF, Frauendorfer K   +31 more
core   +1 more source

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]

, 2013
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas, Thomas eLehrnbecher, Schmidt, Stanislaw, Thomas eKlingebiel, Tramsen, Lars, Lars eTramsen, Klingebiel, Thomas, Stanislaw eSchmidt, Stanislaw Schmidt, Lars Tramsen, Thomas Klingebiel, Thomas Lehrnbecher   +11 more
core   +1 more source

The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor [PDF]

, 2013
Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation.
Dembowsky, K., Dembowsky, Klaus, Romagnoli, B., G Spohn, Karpova, Darja, Patel, K., Chevalier, E., Levesque, J. P., E Chevalier, D Karpova, Patel, Kalpana, Spohn, Gabriele, Romagnoli, Barbara, Schulz, M., Wiercinska, Eliza, Chevalier, Eric, H Bonig, K Dauber, E Wiercinska, J P Levesque, Schulz, Miriam, Chudziak, D., K Dembowsky, Dauber, Katrin, Karpova, D., B Romagnoli, A R Pettit, Wiercinska, E., D Chudziak, Levesque, Jean-Pierre, Bönig, Halvard-Björn, Spohn, G., Pettit, Allison R., M Schulz, K Patel, Bonig, H., Pettit, A. R., Chudziak, Doreen, Dauber, K.   +38 more
core   +1 more source

Hematopoietic chimerism after allogeneic stem cell transplantation : a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ hybridization [PDF]

, 2005
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed mainly in patients with high-risk or advanced hematologic malignancies and congenital or acquired aplastic anemias.
Wachowiak, Jacek, Tomasz Strabel, Peter Bader, Bader, Peter, Jólkowska, Justyna, Jacek Wachowiak, Michał Witt, Anna Pieczonka, Strabel, Tomasz, Pieczonka, Anna, Dariusz Boruczkowski, Boruczkowski, Dariusz, Justyna Jółkowska, Witt, Michal   +13 more
core   +2 more sources

Hematopoietic stem cells for transplantation [PDF]

Nature Immunology, 2002
Multiple sources of HSCs exist. Here, Verfaillie discusses the long-term engraftment capabilities of each source and the search for ex vivo expansion conditions to allow bulk culture for therapeutic HSC transplantation.
openaire   +3 more sources