Results 11 to 20 of about 149,361 (217)

Severe infections and infection-related mortality in a large series of haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide [PDF]

, 2021
Severe infections and their attributable mortality are major complications in recipients of allogeneic hematopoietic stem cell transplantation (alloSCT). We herein report 236 adult patients who received haploSCT with PTCy.
Martino Bofarull, Rodrigo, Sierra, Jorge, Sánchez Ortega, Isabel, Esquirol, Albert, García Cadenas, Irene, Herruzo, Beatriz, Universitat Autònoma de Barcelona. Departament de Medicina, Pérez, Ariadna, Parody, Rocío, Spanish Group for Hematopoietic Stem cell Transplantation (GETH), Sanchez-Ortega, Isabel, Garcia-Cadenas, Irene, Kwon, Mi, Hernani, Rafael, Pascual, Maria Jesús, Ferra, Christelle, Dorado, Nieves, Torrent, Anna, Dorado-Herrero, Nieves, Martino, Rodrigo, Spanish Group for Hematopoietic Stem cell Transplantation (GETH)   +20 more
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Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation:a Global Observational Study [PDF]

, 2013
Fifty-five years after publication of the first hematopoietic stem cell transplantation this technique has become an accepted treatment option for defined hematologic and non-hematologic disorders.
Madrigal, Alejandro, Horowitz, Mary, Passweg, Jakob, Bouzas, Luis Fernando, Szer, Jeff, Niederwieser, Dietger, Gratwohl, Alois, Aljurf, Mahmoud, Iida, Minako, Kodera, Yoshihisa, Worldwide Network Blood Marrow Tra, Pasquini, Marcelo C., Marrow Transplantation,, Lipton, Jeff, Worldwide Network of Blood,, Gratwohl, Michael, Baldomero, Helen, Frauendorfer, Karl   +17 more
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Hematopoietic stem cells for transplantation [PDF]

Nature Immunology, 2002
Multiple sources of HSCs exist. Here, Verfaillie discusses the long-term engraftment capabilities of each source and the search for ex vivo expansion conditions to allow bulk culture for therapeutic HSC transplantation.
openaire   +3 more sources

Haploidentical allograft is superior to matched sibling donor allograft in eradicating pre-transplantation minimal residual disease of AML patients as determined by multiparameter flow cytometry: a retrospective and prospective analysis

Journal of Hematology & Oncology, 2017
Background This study compared the effects of pre-transplantation minimal residual disease (pre-MRD) on outcomes in AML patients who underwent human leukocyte antigen-matched sibling donor transplantation (MSDT) or who received unmanipulated ...
Ying-Jun Chang, Yu Wang, Yan-Rong Liu, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei Han, Yu-Qian Sun, Chen-Hua Yan, Fei-Fei Tang, Xiao-Dong Mo, Kai-Yan Liu, Xiao-Jun Huang   +14 more
doaj   +1 more source

Compassionate use of ruxolitinib in acute and chronic graft versus host disease refractory both to corticosteroids and extracorporeal photopheresis

Experimental Hematology & Oncology, 2017
Background Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have
Mauricio Sarmiento Maldonado, Pablo Ramírez Villanueva, Pablo Bertín Cortes-Monroy, Veronica Jara Arias, Katherine Soto Donoso, Pablo Uribe Gonzalez, Mauricio Ocqueteau Tachini, Jose Antonio Perez-Simón   +7 more
doaj   +1 more source

Identification of the niche and phenotype of the first human hematopoietic stem cells [PDF]

, 2014
In various vertebrate species, the dorsal aorta (Ao) is the site of specification of adult hematopoietic stem cells (HSCs). It has been observed that the upregulation of essential hematopoietic transcription factors and the formation of specific intra ...
Stanislav Rybtsov, Anderson, Richard A., Turner, Marc L., Anderson, Richard A, Ivanovs, Andrejs, Andrejs Ivanovs, Richard A. Anderson, Turner, Marc L, Marc L. Turner, Alexander Medvinsky, Medvinsky, Alexander, Rybtsov, Stanislav   +11 more
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Correction to: Minimal residual disease- and graft-vs.-host disease-guided multiple consolidation chemotherapy and donor lymphocyte infusion prevent second acute leukemia relapse after allotransplant

Journal of Hematology & Oncology, 2019
The original article [1] contains two errors in the MRD Testing sub-section of the Methods:
Chen-Hua Yan, Yu Wang, Jing-Zhi Wang, Yu-Hong Chen, Yao Chen, Feng-rong Wang, Yu-Qian Sun, Xiao-Dong Mo, Wei Han, Huan Chen, Xiao-hui Zhang, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang   +13 more
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Single-cell heterogeneity and dynamic evolution of Ph-like acute lymphoblastic leukemia patient with novel TPR-PDGFRB fusion gene

Experimental Hematology & Oncology, 2023
Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a refractory and recurrent subtype of B-cell ALL enriched with kinase-activating rearrangements.
Xuehong Zhang, Zhijie Hou, Dan Huang, Furong Wang, Beibei Gao, Chengtao Zhang, Dong Zhou, Jiacheng Lou, Haina Wang, Yuan Gao, Zhijie Kang, Ying Lu, Quentin Liu, Jinsong Yan   +13 more
doaj   +1 more source

CMV IN HEMATOPOIETIC STEM CELL TRANSPLANTATION [PDF]

Mediterranean Journal of Hematology and Infectious Diseases, 2016
Due to its negative impact in the outcome of stem cell transplant (SCT) and solid organ transplant patients (SOT) CMV has been called “the troll of transplantation”. One of the greatest advances in the management of SCT has been the introduction of the preemptive strategy.
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Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1 [PDF]

, 2007
Background: AML1/RUNX1 is the most frequently mutated gene in leukaemia and is central to the normal biology of hematopoietic stem and progenitor cells. However, the role of different AML1 isoforms within these primitive compartments is unclear.
Hong, DL, Shinobu Tsuzuki, Tsuzuki, S, Dengli Hong, Enver Tariq, Tsuzuki Shinobu, Matsuo Keitaro, Keitaro Matsuo, Tariq Enver, Hong Dengli, Seto Masao, Rajeev Gupta, Matsuo, K, Gupta Rajeev, Gupta, R, Seto, M, Hong, D, Enver, T, Masao Seto   +18 more
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