Prophylactic donor lymphocyte infusions after first allogeneic hematopoietic stem cell transplantation in children with acute leukemia. [PDF]
Wei A +14 more
europepmc +1 more source
Abstract Background Diagnosing malnutrition in patients with pediatric cancer is challenging because tumor masses can interfere with anthropometric measurements. STRONGkids considers cancer a general risk factor, whereas Screening Tool for Childhood Cancer (SCAN) classifies patients as at risk or not, potentially missing those who need nutrition ...
Cristiane Ferreira Marçon +2 more
wiley +1 more source
Incidence and clinical relevance of donor-derived recipient-specific anti-HLA antibodies in haploidentical hematopoietic stem cell transplantation: a retrospective study. [PDF]
Huang X +7 more
europepmc +1 more source
Regulatory B cells in the central nervous system: From immune regulation to neuroprotection
Neuroinflammatory mechanisms and the therapeutic potential of regulatory B cells (Bregs). Following brain Injury (left panel) blood–brain barrier disruption facilitates the infiltration of peripheral leukocytes, including effector B cells (Beff) and effector T cells (Teff). This process triggers the activation of macrophages, astrocytes, and microglia,
Luiza Stanaszek, Miroslaw Janowski
wiley +1 more source
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar +8 more
wiley +1 more source
Immune cell reconstitution after allogeneic hematopoietic stem cell transplantation in children with β-thalassemia major. [PDF]
Zhou Y +7 more
europepmc +1 more source
Hemophilia A: An Ideal Disease for Prenatal Therapy
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada +2 more
wiley +1 more source
Longitudinal assessment of oral intake adequacy and nutrition-impacted symptoms in patients undergoing allogeneic hematopoietic stem cell transplantation. [PDF]
Qin L, Li R, Wu J, He Y.
europepmc +1 more source
Diagnosis and Management of Prenatal Hereditary Pyropoikilocytosis
ABSTRACT Hereditary pyropoikilocytosis (HPP) is a severe hemolytic anemia caused by variants in SPTA1, SPTB, and EPB41. These weaken horizontal interactions in the erythrocyte cytoskeleton, causing membrane fragmentation and splenic sequestration. It will readily cause fetal anemia and often hydrops fetalis. Prenatal diagnosis requires first ruling out
Connor Hartzell +6 more
wiley +1 more source
Allogeneic Hematopoietic Stem Cell Transplantation for Older Patients with Hematological Malignancies. [PDF]
Kawamura K.
europepmc +1 more source

