Results 51 to 60 of about 540,232 (408)

Isoform-specific potentiation of stem and progenitor cell engraftment by AML1/RUNX1 [PDF]

, 2007
Background: AML1/RUNX1 is the most frequently mutated gene in leukaemia and is central to the normal biology of hematopoietic stem and progenitor cells. However, the role of different AML1 isoforms within these primitive compartments is unclear.
Ailles, Bae, Blyth, Brunstein, Cai, Calkhoven, Cantor, Cashman, Chickarmane, Christiansen, de Bruijn, de Guzman, de Wynter, Demaison, Dengli Hong, Elaine Dzierzak, Freyssinier, Friedman, Fujita, Growney, Guenechea, Harada, Ichikawa, Imai, Ito, Itoh, Jin, Kasugai, Keitaro Matsuo, Levanon, Ling, Masao Seto, Miyoshi, Miyoshi, Mulloy, Nakase, Nishihara, Nishimura, Niwa, North, North, O&apos, Ohkawara, Okuda, Okuda, Osato, Persons, Piacibello, Putz, Rajeev Gupta, Reif, Rodrigues, Sasaki, Schwieger, Shinobu Tsuzuki, Song, Sorrentino, Speck, Stirewalt, Sun, Sun, Swiers, Tanaka, Tariq Enver, Taussig, Tonnelle, Tsuzuki, Wang, Wechsler, Xu, Yagi, Yin, Zhang   +72 more
core   +3 more sources

Busulfan in Hematopoietic Stem Cell Transplantation

Biology of Blood and Marrow Transplantation, 2009
The development of intravenous busulfan (Bu) and its incorporation in the preparative regimens for allogeneic stem cell transplantation has changed transplantation for myelogenous malignancies. Bypassing the oral route to achieve 100% bioavailability translated into improved control over drug administration, with increased safety and reliability of ...
Borje S. Andersson, Stefan O. Ciurea
openaire   +3 more sources

Combinations of antioxidants and/or of epigenetic enzyme inhibitors allow for enhanced collection of mouse bone marrow hematopoietic stem cells in ambient air [PDF]

, 2018
Hematopoietic cell transplantation (HCT) is a treatment for malignant and non-malignant disorders. However, sometimes the numbers of donor hematopoietic stem cells (HSC) are limiting, which can compromise the success of HCT.
Broxmeyer, H.E., Cai, Q., Capitano, M., Cooper, S., Guo, B., Huang, X.   +5 more
core   +1 more source

Hematopoietic stem cell transplantation in Egypt [PDF]

Bone Marrow Transplantation, 2008
Hematopoietic SCT is now an established treatment modality with definitive indications for many hematological disorders. However, this line of treatment requires tremendous resources, and it becomes increasingly difficult for transplanters practicing in the developing world to reconcile the difference between what is possible and what is available.
A Sobhy, Amr Nassar, Hossam K. Mahmoud, Almetwaly M. Sultan, Alaa Elhaddad, Mohamed Elemary, Mohamed Abdel-Mooti, Omar Fahmy   +7 more
openaire   +3 more sources

Thymopoiesis in Pre- and Post-Hematopoietic Stem Cell Transplantation

Frontiers in Immunology, 2018
Hematopoietic stem cell transplantation (HSCT) is an important therapeutic option for some hematological diseases. However, patients who undergo HSCT acquire a state of immunodeficiency that causes significant mortality. Reconstitution of thymic function
Luis Klaus A. da Rocha, Samar Freschi de Barros, Francine Bandeira, Alexia Bollini, Lucia Helena de A. Testa, Anderson João Simione, Marina de O. e Souza, Lilian P. Zanetti, Leila Cibele S. de Oliveira, Ana Claúdia F. dos Santos, Mair Pedro de Souza, Vergílio Antônio R. Colturado, Jorge Kalil, Clarisse M. Machado, Luiza Guilherme   +14 more
doaj   +1 more source

Benchmarking survival outcomes: A funnel plot for survival data [PDF]

arXiv, 2021
Benchmarking is commonly used in many healthcare settings to monitor clinical performance, with the aim of increasing cost-effectiveness and safe care of patients. The funnel plot is a popular tool in visualizing the performance of a healthcare center in relation to other centers and to a target, taking into account statistical uncertainty.
arxiv  

Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually

Bone Marrow Transplantation, 2016
A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant
Jakob R. Passweg, H. Baldomero, P. Bader, C. Bonini, S. Cesaro, P. Dreger, R. Duarte, C. Dufour, J. Kuball, D. Farge-Bancel, A. Gennery, N. Kröger, F. Lanza, A. Nagler, A. Sureda, M. Mohty   +15 more
semanticscholar   +1 more source

Quality of Life and psychopathology in adults who underwent Hematopoietic Stem Cell Transplantation (HSCT) in childhood: a qualitative and quantitative analysis. [PDF]

, 2017
Background: Patients who undergo pediatric Hematopoietic Stem Cell Transplantation (HSCT) may experience long-term psychological sequelae and poor Quality of Life (QoL) in adulthood. This study aimed to investigate subjective illness experience, QoL, and
Basso, G., Boscolo, Valentina, Calore, E., Cattelan, C., Di Florio, N., Mainardi, C., Marzollo, A., Messina, C., Pillon, M., Porreca, A., Sinatora, F., Traverso, A., Tremolada, M., Zanato, S.   +13 more
core   +2 more sources

Comparison between different reduced intensity conditioning regimens in AML/MDS patients in a Latin American center of adult stem cell transplantation

Hematology
Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for several hematological diseases. Prospective and retrospective studies have associated myeloablative conditioning regimens with increased non-relapse ...
José Salinas, Yorman Flores, Patricio Rojas, Catherine Gutierrez, Marcela Vidal, Verónica Jara, James Campbell, María José García, Vicente Sandoval, Maximiliano Vergara, Mauricio Ocqueteau, Felipe Palacios, Mauricio Sarmiento   +12 more
doaj   +1 more source

Effect of Inpatient Palliative Care on Quality of Life 2 Weeks After Hematopoietic Stem Cell Transplantation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2016
Importance During hospitalization for hematopoietic stem cell transplantation (HCT), patients receive high-dose chemotherapy before transplantation and experience significant physical and psychological symptoms and poor quality of life (QOL ...
A. El-Jawahri, T. Leblanc, Harry Vandusen, L. Traeger, J. Greer, W. Pirl, V. Jackson, Jason Telles, Alison M. Rhodes, T. Spitzer, S. Mcafee, Yi-Bin Chen, Stephanie S Lee, J. Temel   +13 more
semanticscholar   +1 more source