Results 51 to 60 of about 507,539 (260)

Low-dose post-transplant cyclophosphamide can mitigate GVHD and enhance the G-CSF/ATG induced GVHD protective activity and improve haploidentical transplant outcomes

OncoImmunology, 2017
Use of high-dose, post-transplant cyclophosphamide (PTCy) results in low rates of graft-versus-host-disease (GVHD) and favorable immune reconstitution, although with higher rates of relapse and somewhat high rates of graft failure.
Yu Wang, Ying-Jun Chang, Lu Chen, Lan-Ping Xu, Zhi-Lei Bian, Xiao-Hui Zhang, Chen-Hua Yan, Kai-Yan Liu, Xiao-Jun Huang   +8 more
doaj   +1 more source

Efficacy of antibiotic prophylaxis in patients with cancer and hematopoietic stem cell transplantation recipients: A systematic review of randomized trials

Cancer Medicine, 2019
To determine the efficacy and safety of different prophylactic systemic antibiotics in adult and pediatric patients receiving chemotherapy or undergoing hematopoietic stem cell transplantation (HSCT).
Grace Egan, P. Robinson, J. P. Martínez, S. Alexander, R. Ammann, L. Dupuis, B. Fisher, T. Lehrnbecher, B. Phillips, Sandra Cabral, G. Tomlinson, L. Sung   +11 more
semanticscholar   +1 more source

Polymorphism in TGFB1 is associated with worse non-relapse mortality and overall survival after stem cell transplantation with unrelated donors. [PDF]

, 2015
Transforming growth factor beta-1, encoded by the TGFB1 gene, is a cytokine that plays a central role in many physiological and pathogenic processes.
Apperley, JF, Arrieta-Bolaños, E, Kirkland, K, Mackinnon, S, Madrigal, JA, Marks, DI, Marsh, SG, Mayor, NP, McQuaker, G, Perry, J, Potter, MN, Russell, NH, Shaw, BE, Thomson, K   +13 more
core   +2 more sources

Phase 2 Study of Anti-Human Cytomegalovirus Monoclonal Antibodies for Prophylaxis in Hematopoietic Cell Transplantation. [PDF]

, 2020
Human cytomegalovirus (HCMV) can cause significant disease in immunocompromised patients, and treatment options are limited by toxicities. CSJ148 is a combination of two anti-HCMV human monoclonal antibodies (LJP538 and LJP539) that bind to and inhibit ...
Akard, Luke, Chemaly, Roy, Christoph, Sandra, Gerbitz, Armin, Hiemenz, John, Holler, Ernst, Hwang, William YK, Jang, Junho, Koh, Liang Piu, Lee, Dong-Gun, Logan, Aaron C, Long, Gwynn, Maertens, Johan, Mielke, Stephan, Pertel, Peter, Ramachandra, Sangana, Segal, Florencia, Smith, Kristin, Tang, Jih-Luh, Wang, Po-Nan, Winkler, Julia, Yeh, Su-Peng, Yeo, Adeline   +22 more
core   +3 more sources

Fludarabine as a cost-effective adjuvant to enhance engraftment of human normal and malignant hematopoiesis in immunodeficient mice [PDF]

, 2018
There is still an unmet need for xenotransplantation models that efficiently recapitulate normal and malignant human hematopoiesis. Indeed, there are a number of strategies to generate humanized mice and specific protocols, including techniques to ...
A Rambaldi, A Terenzi, AM Carroll, AM Carroll, BS Andersson, CR Giver, D Niederwieser, DA Frank, DE Mosier, E McCormack, F Aversa, IF Khouri, K Tajima, L Luznik, L Weiss, M Furukawa, NC Kirkiles-Smith, S Goyama   +17 more
core   +1 more source

Clinical trial of laronidase in Hurler syndrome after hematopoietic cell transplantation. [PDF]

, 2020
BackgroundMucopolysaccharidosis I (MPS IH) is a lysosomal storage disease treated with hematopoietic cell transplantation (HCT) because it stabilizes cognitive deterioration, but is insufficient to alleviate all somatic manifestations.
A Ghosh, AR Pal, ATS Committee on Proficiency Standards for Clinical Pulmonary Function Laboratories., B Link, Bradley S. Miller, C Peters, C Peters, Chester B. Whitley, DA Stevenson, E Shapiro, E Yasuda, E. Oussoren, EA Braunlin, EA Braunlin, ED Kakkis, EJ Langereis, Elise Northrop, Elizabeth Braunlin, Ellen B. Fung, Ellen Fung, G Malm, I Visigalli, Jakub Tolar, JB Eisengart, JE Wraith, JJ Boelens, JR Hobbs, JS Weisstein, Julie B Eisengart, Julie B. Eisengart, KJ Bjoraker, Kyle Rudser, L Lopez, LA Clarke, LE Polgreen, LE Polgreen, LE Polgreen, Lynda E. Polgreen, M Aldenhoven, M Sifuentes, MA Saif, MD Poe, NE Taylor, NJ Rodgers, Paul J. Orchard, RL Washington, S Laraway, Simon A. Jones, SS Grewal, Troy C. Lund, Weston P. Miller, Y Xue   +51 more
core   +1 more source

Milieu-adopted in vitro and in vivo differentiation of mesenchymal tissues derived from different adult human CD34-negative progenitor cell clones [PDF]

, 2005
Adult mesenchymal stem cells with multilineage differentiation potentially exist in the bone marrow, but have also been isolated from the peripheral blood.
Huss, R., Hutter, J., Krombach, F., Moosmann, S., Moser, C.   +4 more
core   +1 more source

Haploidentical donor is preferred over matched sibling donor for pre-transplantation MRD positive ALL: a phase 3 genetically randomized study

Journal of Hematology & Oncology, 2020
Background Previous reports suggest a benefit associated with haploidentical donor transplantation (HIDT) compared to matched sibling donor transplantation (MSDT) in certain contexts, and the choice of optimal candidates warrants further investigation ...
Ying-Jun Chang, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Huan Chen, Yu-Hong Chen, Feng-Rong Wang, Wei-Han, Yu-Qian Sun, Chen-Hua Yan, Fei-Fei Tang, Xiao-Dong Mo, Yan-Rong Liu, Kai-Yan Liu, Xiao-Jun Huang   +14 more
doaj   +1 more source

Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic? [PDF]

, 2014
Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical systems, especially when outcomes are considered in the context of immune
Buck, Gregory A, Chung, Harold, Clark, William, Jameson-Lee, Max, Kobulnicky, Jared D, Koparde, Vishal, Manjili, Masoud H, McCarty, John, Meier, Jeremy, Neale, Michael C, Roberts, Catherine H, Sabo, Roy T, Salman, Salman, Scalora, Allison, Serrano, Myrna, Sheth, Nihar, Toor, Amir A   +16 more
core   +3 more sources

Dendritic Cells Are Critical for the Activation and Expansion of Vδ2+ T Cells After Allogeneic Hematopoietic Transplantation

Frontiers in Immunology, 2018
γδ T cells perform antitumor and antiviral effector functions and are involved in both innate and adaptive immunity. Vδ2+ T cells represent the predominant γδ T subset in the peripheral blood of healthy subjects. Vδ2+ T cells can be selectively activated
Xiaoyu Wang, Xiaoyu Wang, Jiangying Liu, Haitao Gao, Xiao-Dong Mo, Tingting Han, Lan-Ping Xu, Xiao-Hui Zhang, Xiao-Jun Huang   +8 more
doaj   +1 more source