Results 51 to 60 of about 6,334 (218)

Synthesis and application of new gadolinium-porphyrins as potential MR imaging contrast agents for cancer detection in nude mice [PDF]

, 2001
Two new potential magnetic resonance imaging contrast agents, Gd-hematoporphyrin (Gd-H) and Gd-tetra-carboranylmethoxyphenyl-porphyrin (Gd-TCP), were synthesized and applied to nude mice with human melanoma (MM-138) xenografts.
Allen, B., Shahbazi-Gahrouei, D., Williams, M.   +2 more
core  

Breast cancer as photodynamic therapy target: Enhanced therapeutic efficiency by overview of tumor complexity [PDF]

, 2014
Photodynamic therapy is a minimally invasive and clinically approved procedure for eliminating selected malignant cells with specific light activation of a photosensitizer agent.
Lamberti, María Julia, Rivarola, Viviana, Rumie Vittar, Natalia Belen   +2 more
core   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source

In Vivo Efficacy of Zinc Phthalocyanine Nanocarriers IN Photodynamic Therapy of Cancer

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
Zinc phthalocyanines are photosensitizing agents used in photodynamic therapy. Their incorporation into nanosystems enables their encapsulation, targeting, and functionalization, optimizing their therapeutic activity. The results highlight their therapeutic potential, reinforcing their relevance as an innovative strategy in cancer treatment and as a ...
Adrian Lima Roberto, Kammila Martins Nicolau Costa, Sara Efigênia Dantas de Mendonça y Araújo, Ingrid Larissa da Silva Soares, João Augusto Oshiro‐Junior   +4 more
wiley   +1 more source

Xantenes and porphyrins, photoactivatable molecules used to control insect pests [PDF]

, 2011
Se analizaron dos sensibilizadores fotodinámicos, la Floxina B y la Hematoporfirina IX, como fotoinsecticidas de moscas plagas. Ambas sustancias adicionadas al alimento de las larvas presentaron alta toxicidad.
Bochicchio, Pablo Alejandro, Pujol Lereis, Luciana Mercedes, Rabossi, Alejandro   +2 more
core  

Investigating the photosensitizer-potential of targeted gallium corrole using multimode optical imaging [PDF]

, 2011
We recently developed a novel therapeutic particle, HerGa, for breast cancer treatment and detection. HerGa consists of a tumor-targeted cell penetration protein noncovalently assembled with a gallium-metallated corrole.
Chu, David, Farkas, Daniel L., Gray, Harry B., Gross, Zeev, Hwang, Jae Youn, Lubow, Jay, Medina-Kauwe, Lali K.   +6 more
core   +1 more source

Implanted Miniature Light Devices for Phototherapeutics

Advanced Therapeutics, Volume 9, Issue 1, January 2026.
Modern phototherapeutics has many attractive features; however, the shallow penetration of light into skin and tissue is an inherent physical limitation that restricts usage to superficial sites of disease. To mitigate this major problem, researchers and clinicians are actively developing miniature implanted light devices that can be implanted within a
Hailey S. Sanders, Catherine G. Price, Ana F. de Almeida Barreto, Sunghoon Rho, Thomas D. O'Sullivan, Bradley D. Smith   +5 more
wiley   +1 more source

Photomedicine of the endometrium: experimental concepts [PDF]

, 2017
Gynaecological photomedicine offers new diagnostic and therapeutic methods based on the interaction of light with the reproductive organs. One example is photodynamic therapy (PDT) in which photosensitizers are applied systemically or topically for ...
Berns, Michael W., Haller, Urs, Svaasand, Lars O., Tadir, Yona, Tromberg, Bruce J., Wyss, Marie T., Wyss, Pius   +6 more
core  

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]

, 2012
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Abdulkadir, Abdulkadir, Aggeli, Arsenian, Banks, Baron, Bedadala, Bedard, Bjelakovic, Bjelakovic, Bonventre, Brand, Calogero, Cao, Cao, Chang, Chen, Christy, Christy, Cramer, Datta, Dixit, Dixit, Dyson, Dyson, Eidelman, Elisabeth Deindl, Eto, Eto, Fahmy, Fahmy, Feldman, Forsberg, Förstermann, Gao, Gashler, Hallahan, Halliwell, Harja, Harman, Harrison, Hasan, Hasan, Hebert, Heo, Hill, Hirata, Huang, Irani, Iyoda, Izumi, Judith-Irina Pagel, Katsarou, Kawamura, Khachigian, Khachigian, Konishi, Lee, Liao, Lim, Lukac, Marais, Meira, Nishi, Nose, Nose, Nozik-Grayck, Ohba, Ouellette, Pagel, Paron, Pavletich, Peskin, Pines, Preston, Radisky, Sakamoto, Sattler, Schwachtgen, Sies, Sies, Stuart, Sudenga, Tell, Tell, Tell, Tell, Terashima, Treisman, Tsai-Morris, Vickers, Vivekananthan, Wang, Whitmarsh, Yan, Yan, Yang, Yang, Ye, Yu   +99 more
core   +2 more sources

Flash Photodynamic Therapy – How the Saturation of Photosensitizer Absorption Enables Selective and Deeper Tumor Treatments

Advanced Science, Volume 13, Issue 1, 5 January 2026.
FLASH‐PDT uses strongly‐absorbing photosensitizers and pulsed lasers to saturate the photosensitizer absorption at ≈1‐cm tissue depths. This allows for the generation of [ROS] above the necrosis threshold level for tumors, while maintaining [ROS] in peritumoral tissues below that threshold, even when the tumor‐to‐peritumoral tissue ratio is as low as 2.
Luis G. Arnaut, Fábio A. Schaberle, José Sereno, Lígia C. Gomes‐da‐Silva   +3 more
wiley   +1 more source