Results 41 to 50 of about 3,879 (213)
New insights into epileptic spasm generation and treatment from the TTX animal model
Epilepsia Open, EarlyView.Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann +2 more
wiley +1 more source
False localization of ictal activity by scalp EEG in candidates for hemispherectomy [PDF]
, 1993 Two patients with intractable seizures and large structural lesions were candidates for hemispherectomy for seizure control. Repeated ictal EEGs recorded from scalp falsely localized seizure onset to the contralateral hemisphere. Intracarotid amobarbital
Baram, TZ, Mitchell, WG, Snead, OC
core +1 more source
Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery
Epilepsia Open, EarlyView.Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields +4 more
wiley +1 more source
Pediatric Neurology Briefs, 1992 The surgical outcome in 34 patients between 2 and 15 years of age who were operated on for medically intractable seizures is reported from the Neurosurgical Clinic, University Clinical Center, Visegradska 26, Belgrade, Yugoslavia.
J Gordon Millichap
doaj +1 more source
Hemispherotomy Revised: A complication overview and a systematic review meta-analysis
Brain and Spine, 2023 Introduction: Hemispherectomy/hemispherotomy has been employed in the management of catastrophic epilepsy. However, initial reports on the associated mortality and morbidity raised several concerns regarding the technique's safety.
Maria D. Karagianni +6 more
doaj +1 more source
Life with Cortical Dysplasis. A case study of a sixth grader. [PDF]
, 2015 Cortical Dysplasia is a rare brain malformation that results in multiple life challenges such as hemiparesis (cerebral palsy on half of the body), and seizures.
Gerlach, Brittany
core +1 more source
Arquivos de Neuro-Psiquiatria, 2004 A hemimegalencefalia (HME) é malformação congênita cerebral rara de etiologia desconhecida que pode se apresentar com síndrome epiléptica de início precoce e resistente à terapia com anticonvulsivantes, associada a comprometimento significativo do ...
Luiz Fernando Fonseca +10 more
doaj +1 more source
The lateral dominance in 182 children: 2. the conscious motor action [PDF]
, 1995 The mechanisms and topology of the consciousness phenomenon are briefly presented. The present results and data from literature are used to point out that to localize in one certain part of the cerebrum the conscious process seems untenable.
Jordy, Ceme Ferreira
core +2 more sources
American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 800-806, April 2026.ABSTRACT Smith‐Kingsmore syndrome (SKS) is a rare autosomal dominant condition characterized by neurodevelopmental differences, macrocephaly/megalencephaly, describable facial features, sleep–wake abnormalities, hyperphagia, and overgrowth. SKS is caused by pathogenic gain‐of‐function variants in MTOR which lead to hyperactivation of the mTOR pathway ...
Carolyn R. Raski, Carlos E. Prada
wiley +1 more source
Efficacy of neurosurgical interventions for epilepsy in polymicrogyria: A systematic review
Epilepsia Open, Volume 11, Issue 2, Page 390-408, April 2026.Abstract Polymicrogyria (PMG) is a rare malformation of cortical development (MCD) characterized by abnormal neuronal architecture, often associated with epilepsy. Neurosurgical interventions have been explored, but their effectiveness remains a subject of ongoing research and debate.
Sergio Rinella +4 more
wiley +1 more source