Results 171 to 180 of about 980 (262)

Picture naming: Stereoelectroencephalography and connectivity insights

open access: yesEpilepsia, EarlyView.
Abstract Objective This study investigates the neural substrates of picture naming (PN) using stereoelectroencephalographic (SEEG) stimulations and evaluates the contribution of white matter (WM) fascicles related to the basal temporal language area (BTLA) to the broader functional PN network.
Insafe Mezjan   +4 more
wiley   +1 more source

Corticocortical evoked potential amplitude is altered by cortical stimulation in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Neurostimulation is an established therapy for drug‐resistant epilepsy, but optimizing stimulation parameters remains a major challenge. Corticocortical evoked potential (CCEP) amplitude may serve as an immediate biomarker of neurostimulation effects, enabling rapid parameter optimization.
Bethany J. Stieve   +4 more
wiley   +1 more source

High incidence of Y‐chromosome mosaicism in male and female individuals with mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an underrecognized pediatric cortical lesion associated with somatic X‐linked SLC35A2 variants in approximately 50% of individuals. The genetic etiology in individuals without detectable SLC35A2 mutations remains undefined, which limits
Erica Cecchini   +13 more
wiley   +1 more source

Presurgical magnetoencephalography‐derived network control metrics distinguish successful hippocampal resection vs sparing in temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Surgical decision‐making in temporal lobe epilepsy (TLE) faces a critical challenge in determining whether the hippocampus can be safely spared during anterior temporal resection, particularly when surgery involves the language‐dominant hemisphere.
Guhan Seshadri NP   +6 more
wiley   +1 more source

Individual‐specific resting‐state networks predict language dominance in drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to reliably estimate individual‐specific resting‐state cortical networks and determine whether language network topography can predict task‐based language dominance in drug‐resistant epilepsy. Methods We utilized a multisession hierarchical Bayesian model (MS‐HBM) trained on drug‐resistant epilepsy patients ...
Mervyn Jun Rui Lim   +7 more
wiley   +1 more source

Comparison of volume‐ and surface‐based magnetic resonance imaging morphometry algorithms in the detection of focal cortical dysplasia

open access: yesEpilepsia, EarlyView.
Abstract Objective Detection of focal cortical dysplasia (FCD) remains a major challenge in presurgical epilepsy diagnostics. Magnetic resonance imaging (MRI) morphometry increasingly improves lesion detection and postsurgical outcomes. The volume‐based Morphometric Analysis Program, version 2018 (MAP18) with integrated artificial neural network and ...
Lara Bücheler   +17 more
wiley   +1 more source

Mindfulness meditation increases interictal epileptiform discharges in meditation‐naïve surgical epilepsy patients

open access: yesEpilepsia, EarlyView.
Abstract Objective Meditation has widely recognized psychological and neuromodulatory benefits, yet its effects on epileptiform activity remain unclear. This study examined whether novice meditation modulates interictal epileptiform discharges (IEDs) in patients with drug‐resistant epilepsy using intracranial electroencephalography (iEEG).
Shweta Soni   +5 more
wiley   +1 more source

The dynamic functional connectivity peak index: Detection of interictal epileptic activity with fMRI

open access: yesEpilepsia, EarlyView.
Abstract Objective Epileptogenic zone (EZ) localization is crucial for surgical treatment of patients with medication‐resistant epilepsy. Although simultaneous electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can detect interictal discharges for EZ localization, clinical adoption is limited by the need for specialized ...
Lucas E. Sainburg   +9 more
wiley   +1 more source

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