Results 61 to 70 of about 589 (167)

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

Epilepsia Open, Volume 11, Issue 4, Page 1314-1328, August 2026.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng, Päivi Koroknay‐Pál, Henri Lehtinen, Eija Gaily, Atte Karppinen, Anders Paetau, Olli Tynninen, Heta Leinonen, Aki Laakso, Eeva‐Liisa Metsähonkala   +9 more
wiley   +1 more source

Epilepsy: Epidemiology, Molecular Pathogenesis, and Clinical Management

MedComm, Volume 7, Issue 7, July 2026.
Epilepsy is a heterogeneous and chronically evolving brain network disorder. This review integrates epidemiological burden, psychiatric comorbidities, and cyclic seizure patterns with multiscale pathogenic mechanisms, including ion‐channel dysfunction, synaptic transmission defects, neuroinflammation, metabolic and mitochondrial dysfunction, and ...
Jian Liu, Xinyan Wu, Ting Yin, Feining Huang, Manqi Kong, Yu Yang, Zinan Liu, Jiabin Yu, Tianpeng Zhang   +8 more
wiley   +1 more source

Beyond Broca and Wernicke: Epilepsy surgery in the language areas

Epileptic Disorders, Volume 28, Issue 3, Page 581-601, June 2026.
Abstract Epilepsy surgery in language areas is challenged by the intricacies of presurgical workup and surgical planning. In recent decades, the view of language‐related circuitry has shifted from being localized in a few cortical centers to a distributed, dynamically interconnected system, increasing complexity.
Carmen Barba, Alessandro De Benedictis, Veronica Pelliccia, Domenico Tortora, Federico Melani, Alessandro Consales, Domenica Immacolata Battaglia, Elisabetta Cesaroni, Lorenzo Ferri, Alice Noris, Matteo Pugnaghi, Michele Rizzi, Giuseppe Bertini, Flavio Villani, Laura Tassi, on behalf of Commission of Epilepsy Surgery, Italian League against Epilepsy   +16 more
wiley   +1 more source

Functional hemispherotomy in the treatment of drug-resistant epilepsy: a clinical case

Эпилепсия и пароксизмальные состояния, 2019
Though brain hemiatrophy is not among the leading causes of symptomatic epilepsy; the problem remains important and is of great practical interest to neurologists and neurosurgeons in Russia.
A. A. Sufianov, R. T. Deniel, S. Zh. Stefanov, G. Z. Sufianova, A. S. Orlov, S. V. Churkin, S. I. Kostarev, S. V. Mirkhaydarov   +7 more
doaj   +1 more source

Arterial spin labeling performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography for presurgical evaluation in pediatric lesional epilepsy

Epilepsia, Volume 67, Issue 6, Page 2940-2953, June 2026.
Abstract Objective This study was undertaken to test whether arterial spin labeling (ASL) performs comparably to 2‐[18F]fluoro‐2‐deoxy‐D‐glucose positron emission tomography (FDG‐PET), the mainstay functional imaging technique, in pediatric lesional epilepsy, while avoiding radiotracer exposure and additional sedation.
Antonio Giulio Gennari, Dorottya Cserpan, Raimund Kottke, Niklaus Krayenbühl, Michael Messerli, Martin W. Hüllner, Ruth O'Gorman Tuura, Georgia Ramantani   +7 more
wiley   +1 more source

Expanding the scope of pediatric epilepsy surgery: Access, indications, and outcomes in a modern cohort

Epilepsia Open, Volume 11, Issue 3, Page 935-948, June 2026.
Abstract Objective Expanded indications, diagnostic tools, and treatment options have transformed the landscape of modern pediatric epilepsy surgery. Published real‐world experiences from large surgical cohorts are still needed. To close this gap, we evaluated access, indications, treatment, and outcomes in a contemporary pediatric epilepsy surgery ...
John R. McLaren, William Muñoz, Hunki Kwon, Alexandra L. Geffrey, Pranav Nanda, Ronald Thibert, Lily Grossmann, Steven Stufflebeam, Camilo Jaimes, Britt Carlson Emerton, Kristopher T. Kahle, R. Mark Richardson, Catherine J. Chu   +12 more
wiley   +1 more source

Hemispherotomy in a patient with intractable epilepsy also on anticoagulant therapy for coronary artery aneurysms secondary to Kawasaki disease - Proposal of an ethical approach

Interdisciplinary Neurosurgery, 2017
Purpose: To describe the safe performance of epilepsy surgery in a patient on anticoagulant therapy. Patient and method: An 11-year-old girl developed Kawasaki disease, which caused coronary artery aneurysms.
Ayataka Fujimoto, Hirotaka Motoi, Tohru Okanishi, Yoshiki Mori, Ryo Sugiura, Toshiaki Oka, Masaaki Koide, Hideo Enoki, Tokutaro Tanaka   +8 more
doaj   +1 more source

Functional hemispherotomy in Rasmussen syndrome in the absence of classic MRI findings

Epilepsy and Behavior Case Reports, 2017
A 7-year-old previously healthy girl presented with a left-sided focal seizure without impaired consciousness and subsequently developed epilepsia partialis continua.
Yasunori Nagahama, Charuta Joshi, Brian Dlouhy, Angela Y. Wu, Taylor J. Abel, Gary Baumbach, Hiroto Kawasaki   +6 more
doaj   +1 more source

A 5‐year‐old boy with super‐refractory status epilepticus and RANBP2 variant warranting life‐saving hemispherotomy

Epilepsia Open
Focal cortical dysplasia (FCD) represents the most common cause of drug‐resistant epilepsy in adult and pediatric surgical series. However, genetic factors contributing to severe phenotypes of FCD remain unknown.
Barbora Straka, Miroslav Koblížek, Barbora Splítková, Radka Valkovičová, Lenka Krsková, Markéta Kalinová, Markéta Vlčková, Josef Zámečník, Petra Laššuthová, Lucie Sedláčková, David Staněk, Alice Maulisová, Michal Tichý, Martin Kynčl, Pavel Kršek   +14 more
doaj   +1 more source

Delayed diagnosis of shunt overdrainage following functional hemispherotomy and ventriculoperitoneal shunt placement in a hemimegalencephaly patient

Epilepsy and Behavior Case Reports, 2017
Shunt overdrainage represents a nebulous condition of variable clinical and imaging presentations, where the diagnosis is primarily clinical. The condition presents a diagnostic challenge particularly in patients with cognitive impairment and ...
Yasunori Nagahama, David Peters, Sho Kumonda, Adam Vesole, Charuta Joshi, Brian J. Dlouhy, Hiroto Kawasaki   +6 more
doaj   +1 more source