Results 51 to 60 of about 265,437 (286)

Effects of Renal and Hepatic Impairment on the Pharmacokinetics of Zilurgisertib

British Journal of Clinical Pharmacology, EarlyView.
Aim Small‐molecule activin receptor‐like kinase‐2 inhibitor zilurgisertib (INCB000928) is under investigation in a pivotal trial for the treatment of fibrodysplasia ossificans progressiva (FOP), an ultrarare genetic condition. This analysis assessed effects of renal and hepatic impairment on zilurgisertib pharmacokinetics.
Yan‐ou Yang, Yunlan Fang, Phillip Wang, Xiang Liu, Jay Getsy, Kevin Rockich   +5 more
wiley   +1 more source

Disease severity adversely affects delivery of dialysis in acute renal failure [PDF]

, 2007
Background/Aims: Methods of intermittent hemodialysis (IHD) dose quantification in acute renal failure (ARF) are not well defined. This observational study was designed to evaluate the impact of disease activity on delivered single pool Kt/V-urea in ARF ...
American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference, Clark WR, Daugirdas JT, Daugirdas JT, Evanson JA, Evanson JA, Helmut Schiffl, Himmelfarb J, Ikizler TA, Jaber BL, Kanagasundaram NS, Klouche K, Knaus WA, Leblanc M, Liangos O, Marshall MR, Paganini EP, Paganini EP, Saudan P, Watson PE, Weisbord SD   +20 more
core   +1 more source

Renal Arterial Anatomy: Implications for Normothermic Machine Perfusion in Renal Transplantation

Clinical Anatomy, EarlyView.
ABSTRACT Normothermic machine perfusion (NMP) is a novel technology that has shown potential in viability assessment and reconditioning of donor organs. Normothermic machine perfusion is technically more challenging in kidneys with multiple renal arteries (RAs).
Lily Mae Miller, Peter Douglas, Julie Glen, Emma Aitken   +3 more
wiley   +1 more source

Mucocutaneous manifestations and nail changes in patients with end-stage renal disease on hemodialysis. [PDF]

, 2013
Mucocutaneous manifestations are common among patients on hemodialysis (HD). This study was undertaken to determine the prevalence of mucocutaneous manifestations in patients with end-stage renal disease (ESRD) who are on HD.
Azarhoosh, R., Dehghan, M., Haghighi, A.N., Kabootari, M., Qorbani, M., Sadani, S., Tajbakhsh, R., Zadeh, S.S.   +7 more
core   +5 more sources

Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure [PDF]

, 2002
Background: The cytotoxic treatment of patients suffering from advanced or metastatic cancer undergoing hemodialysis due to chronic renal failure still remains a problem, since for those patients pharmacokinetic and pharmacodynamic data on most cytotoxic
Hacker, U., Heinemann, Volker, Schalhorn, A., Stemmler, J., Weise, A.   +4 more
core   +1 more source

TAVR in Male Patients With Large Aortic Valve Annuli: A Propensity‐Matched Analysis of Balloon‐Expandable Versus Self‐Expanding Valves

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Trans‐catheter aortic valve replacement (TAVR) in patients with large annuli poses procedural difficulties and possible complications. Aims We sought to compare the peri‐procedural and long‐term outcomes of patients with large annuli undergoing TAVR with self‐expanding (SEV) versus balloon‐expandable (BEV) valves.
Lior Zornitzki, Itamar Loewenstein, Shir Frydman, Maayan Konigstein, Jeremy Ben‐Shoshan, Yaron Arbel, Israel Barbash, Ran Kornowski, Gabby G. Elbaz, Danny Dvir, Ariel Finkelstein, Shmuel Banai, Arie Steinvil   +12 more
wiley   +1 more source

Determinants of dialysis adequacy in maintenance hemodialysis patients: a cross-sectional study on modifiable risk factors and clinical interventions

BMC Nephrology
Background Dialysis adequacy is crucial for maintaining the health and quality of life of patients undergoing maintenance hemodialysis (MHD). Assessing its current status and identifying influencing factors is essential for optimizing treatment outcomes.
Wanning Jia, Wenwen He, Zhuozhuo Chen, Haiyan Wang, Haitao Lu   +4 more
doaj   +1 more source

Clinical Conditions and History of Illness Among Terminal Chronic Kidney Disease Patients [PDF]

, 2019
End-stage renal disease (ESRD) is one of the public health problems in Indonesia. This study aimed to determine the clinical condition of premorbid and the incidence of ESRD. The study design is a case-control.
Adiningrat, A. (Arya), Akrom, A. (Akrom), Hidayati, T. (Titiek)   +2 more
core   +4 more sources

Consumed by Abdominal Distention

Arthritis Care &Research, Accepted Article.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

The Verification of Co‐Axiality of the Three Self‐Expanding Transcatheter Aortic Valve Systems According to the Difference in Shaft Spine

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Accurate bioprosthesis implantation depth during transcatheter aortic valve replacement (TAVR) is crucial for optimal outcomes. Self‐expanding valves (SEVs) have evolved delivery catheter designs, from a double spine shaft in Evolut PRO+ (PRO + ) to single spine in Evolut FX (FX) and non‐spine in Navitor, to improve access ...
Yun Teng, Yusuke Enta, Makoto Saigan, Natsuko Satomi, Yuta Kobayashi, Masaki Nakashima, Momo Kosuga, Manabu Maeda, Yusuke Toki, Yoshiko Munehisa, Masaki Miyasaka, Masataka Taguri, Shigeru Toyoda, Norio Tada   +13 more
wiley   +1 more source