IntroductionMinimal residual disease (MRD) is commonly assessed in bone marrow (BM) aspirate. However, sample quality can impair the MRD measurement, leading to underestimated residual cells and to false negative results.
Ilaria Vigliotta+38 more
doaj +1 more source
Acute normovolemic hemodilution [PDF]
Patients and physicians continue to be motivated to find methods to reduce the use of allogeneic blood. Even though donor screening has increased the safety of donated blood products, autologous blood is the most desirable source of red cells during the perioperative period.
Aryeh Shander, Tanuja S. Rijhwani
openaire +6 more sources
Objective To examine the impact of hemodilution on components of blood coagulation using rotational thromboelastometry (ROTEM®) in term parturients Methods This is a prospective, observational pilot study including 35 healthy, parturients at term (≥37 ...
C. Getrajdman+3 more
semanticscholar +1 more source
Nitric oxide synthase inhibition attenuates cardiac response to hemodilution with viscogenic plasma expander. [PDF]
Background and objectivesIncreased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution.
Cabrales, Pedro, Chatpun, Surapong
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The choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs [PDF]
The correction of hypovolemia with acellular fluids results in acute normovolemic anemia. Whether the choice of the infusion fluid has an impact on the maintenance of oxygen (O2) supply during acute normovolemic anemia has not been investigated so far ...
Habler, Oliver+7 more
core +2 more sources
Hepatocyte-derived IL-10 plays a crucial role in attenuating pathogenicity during the chronic phase of T. congolense infection [PDF]
Bovine African Trypanosomosis is an infectious parasitic disease affecting livestock productivity and thereby impairing the economic development of Sub-Saharan Africa. The most important trypanosome species implicated is T.
Brys, Lea+6 more
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Effect of stress doses of hydrocortisone on S-100B vs. interleukin-8 and polymorphonuclear elastase levels in human septic shock [PDF]
Stress doses of hydrocortisone a re known to have immunomodulatory effects in patients with hyperdynamic septic shock. The prognosis correlates with the presence and severity of septic encephalopathy. However, neurological evaluation is influenced by the
Anderson+46 more
core +2 more sources
OBJECTIVE: The net effects of acute normovolemic hemodilution with different hemoglobin levels on splanchnic perfusion have not been elucidated. The hypothesis that during moderate and severe normovolemic hemodilution, systemic and splanchnic hemodynamic
Daniel Perin+3 more
doaj +1 more source
Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape+46 more
core +1 more source
Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies. [PDF]
At least a third of the blood supply in the world is used to transfuse 1-2 units of packed red blood cells for each intervention and most clinical trials of blood substitutes have been carried out at this level of oxygen carrying capacity (OCC ...
Acharya, Seetharama A+7 more
core +3 more sources