Results 21 to 30 of about 519,711 (283)

Liraglutide improves liver microvascular dysfunction in cirrhosis: Evidence from translational studies

open access: yesScientific Reports, 2017
Hepatic stellate cells (HSC) play a key role in the development of chronic liver disease (CLD). Liraglutide, well-established in type 2 diabetes, showed anti-inflammatory and anti-oxidant properties.
Fernanda Cristina de Mesquita   +11 more
doaj   +1 more source

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension [PDF]

open access: yes, 2015
The effects of increased intra-abdominal pressure (IAP) on cardiovascular function are well recognized and include a combined negative effect on preload, afterload and contractility.
De Keulenaer, Bart L   +2 more
core   +1 more source

Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

open access: yesHepatology Communications, 2019
In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension.
Jordi Gracia‐Sancho   +11 more
doaj   +1 more source

Evaluation of Hemodynamic Changes in Retrobulbar Blood Vessels Using Color Doppler Imaging in Diabetic Patients

open access: yesLife, 2022
Background—Diabetic retinopathy is a common complication of long-standing hyperglycemia. Microangiopathy-induced retinal changes are well-visualized on ophthalmoscopic examination. However, certain hemodynamic alterations have also been documented in the
Gulshan Madhpuriya   +4 more
doaj   +1 more source

New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease

open access: yesCells, 2019
Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. However, most available animal models fail to reflect the whole spectrum of the disease.
Raquel Maeso-Díaz   +6 more
doaj   +1 more source

Higher plasma fibroblast growth factor 23 levels are associated with a higher risk profile in pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2019
Metabolic abnormalities are proposed to contribute to pulmonary arterial as well as right ventricular remodelling in pulmonary arterial hypertension. Among the proposed abnormalities are altered glucose and lipid processing, mitochondrial malfunction ...
Habib Bouzina   +2 more
doaj   +1 more source

ECMO-assisted resection of huge thoracic mass [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2018
Some advanced thoracic malignancy cannot be resected safely by using of conventional ventilation, so some sort of cardiopulmonary support is needed for hemodynamic and ventilation management of the patient. Using extracorporeal membrane oxygenation (ECMO)
Alireza Jahangirifard   +4 more
doaj   +1 more source

Regularized brain reading with shrinkage and smoothing [PDF]

open access: yes, 2016
Functional neuroimaging measures how the brain responds to complex stimuli. However, sample sizes are modest, noise is substantial, and stimuli are high dimensional. Hence, direct estimates are inherently imprecise and call for regularization. We compare
Ramdas, Aaditya   +3 more
core   +1 more source

Late Diagnosis of Anomalous Aortic Origin of a Coronary Artery from the Inappropriate Sinus of Valsalva during Investigation of Chest Pain

open access: yesCase Reports in Cardiology, 2018
In this work are reported two cases of anomalous aortic origin of a coronary artery (AAOCA), with the left main coronary artery (LMCA) arising at the right sinus of Valsalva in a 77-year-old woman and in a 79-year-old man submitted to angiography after ...
Brunna Priscylla Américo Carvalho   +7 more
doaj   +1 more source

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