Results 41 to 50 of about 115,843 (292)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Evaluation of the acute effects of smoking on cardiac electrical function and hemodynamic indices in smokers

طب اورژانس ایران
Background: Smoking is one of the most important risk factors for cardiovascular diseases. Although numerous studies have evaluated the long-term consequences of smoking, few studies have assessed the short-term effects of smoking, especially on the ...
Mehdi Pishgahi, Sepideh Shahi, Rama Bozorgmehr, Kimia Karimi Toudeshki, Shirin Ghane Fard, Mina Mirzaei Pirloo   +5 more
doaj   +3 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Standards for the Application of Hemodynamic Monitoring Technology in Critical Care

Xiehe Yixue Zazhi
With the rapid advancement of hemodynamic indices and monitoring technologies, their classification methods and application processes have become increasingly complex.
ZHAO Hua, ZHANG Hongmin, DING Xin, CHEN Huan, DUAN Jun, DU Wei, TANG Bo, ZHOU Yuankai, LI Dongkai, WANG Xinchen, WANG Cui, ZHOU Gaosheng, WANG Xiaoting, Critical Hemodynamic Therapy Collaborative Group, Critical Care Ultrasound Study Group   +14 more
doaj   +1 more source

Cardiac Function in Brain Death, Usage of Advanced Hemodynamic Monitoring

Archives of Anesthesia and Critical Care, 2022
Background: This study used advanced hemodynamic monitoring along with simultaneous echocardiography to assess donated heart function of brain death patients using advanced hemodynamic monitoring and its efficacy in organ donation.
Alireza Jahangirifard, Fateme Monjazebi, Alireza Ilbeigi, Nafiseh Naghdipour, Zargham Hossein Ahmadi, Farahnaz Sadegh Beigee, Sanaz Dehghani   +6 more
doaj   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Types of hemodynamic response to orthostasis according to continuous blood pressure monitoring: a case series of heart failure with reduced ejection fraction

Российский кардиологический журнал, 2021
Heart failure (HF) is associated with unfavorable outcomes and high health care costs. Determination of the hemodynamic response to orthostasis can be an additional tool in assessing the stability and compensation of HF patients. Active orthostatic test (
D. N. Fedorova, A. E. Solovieva, V. L. Galenko, A. V. Kozlenok, A. V. Berezina, S. V. Villevalde   +5 more
doaj   +1 more source

Noninvasive continuous hemodynamic monitoring

, 2012
Monitoring of continuous blood pressure and cardiac output is important to prevent hypoperfusion and to guide fluid administration, but only few patients receive such monitoring due to the invasive nature of most of the methods presently available ...
Wesselink, Wilbert A., Wilbert A. Wesselink, Truijen, Jasper, Westerhof, Berend E., Jasper Truijen, Berend E. Westerhof, Johannes J. van Lieshout, van Lieshout, Johannes J.   +7 more
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]

, 2014
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
Vitón-Castillo, Adrián Alejandro, Mebazaa, A, Mebazaa, A. (Alexandre), Antonelli, M, Rhodes, A. (Andrew), Backer, D. (Daniel) de, Pinsky, MR, Teboul, JL, Bakker, J. (Jan), Vincent, JL, Pinsky, Michaël, Christoph Hofer, Jean Louis Vincent, Teboul, J.L. (Jean Louis), Beale, R, Daniel De Backer, Jaeschke, R, Rhodes, A, Jaeschke, Roman, Hofer, C, Jaeschke, R. (Roman), Teboul, Jean Louis, Mebazaa, Alexandre, Cecconi, M. (Maurizio), De Backer, Daniel, Antonelli, Massimo, Massimo Antonelli, Antonelli, M. (Massimo), Viruez-Soto, José Antonio, Bakker, Jan, Hofer, C. (Christoph), Auza-Santivañez, Jhossmar Cristians, Maurizio Cecconi, Vincent, J.-L. (Jean-Louis), Jean Louis Teboul, Roman Jaeschke, Beale, R. (Richard), Vincent, Jean Louis, Hofer, Christoph, Pinsky, M.R. (Michael), Michael R. Pinsky, Bakker, J, Richard Beale, Rhodes, Andrew, Alexandre Mebazaa, Luperón Loforte, Daysi, Cecconi, M, De Backer, D, Jan Bakker, Beale, Richard, Bakker, Jan; id_orcid, Cecconi, Maurizio, Andrew Rhodes   +52 more
core   +1 more source