Results 171 to 180 of about 8,458,968 (398)

Effect of long‐term voclosporin treatment on renal histology in patients with active lupus nephritis with repeat renal biopsies

open access: yesArthritis &Rheumatology, Accepted Article.
Objective This study characterized the impact of voclosporin on kidney histology in patients with lupus nephritis (LN) who had protocolized repeat kidney biopsies in the AURORA clinical trials. Methods Patients were randomized to voclosporin or placebo treatment for up to three years; all patients received mycophenolate mofetil and low‐dose ...
Brad H. Rovin   +9 more
wiley   +1 more source

Impact of Interleukin‐1 Blockade on the Development of Macrophage Activation Syndrome in Still's Disease: Incidence and Diagnostic Validity of the EULAR/ACR/PRINTO 2016 MAS Classification Criteria

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To evaluate the applicability of the 2016 EULAR/ACR/PRINTO macrophage activation syndrome (MAS) classification criteria in patients with Still's disease (sJIA‐SD) treated with IL‐1‐targeted therapy and to assess the incidence of MAS in this context.
Remco G.A. Erkens   +14 more
wiley   +1 more source

Variability in intestinal drug metabolizing enzymes and transporters in Crohn's disease and potential impact on oral drug absorption

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The aim of study was to generate quantitative data on the abundance of drug‐metabolizing enzymes and transporters (DMETs) in inflamed and non‐inflamed Crohn's disease (CD) ileum and colon, for incorporation into physiologically based pharmacokinetic (PBPK) models, enabling prediction of oral drugs' pharmacokinetics (PK) perturbation in CD patients.
Sarah Alrubia   +4 more
wiley   +1 more source

Renal Hemodynamic Responses to Stress in Normotensive and Hypertensive Subjects [PDF]

open access: bronze, 1960
C.T. Bello   +4 more
openalex   +1 more source

AbsoluteNet: A Deep Learning Neural Network to Classify Cerebral Hemodynamic Responses of Auditory Processing [PDF]

open access: yesarXiv
In recent years, deep learning (DL) approaches have demonstrated promising results in decoding hemodynamic responses captured by functional near-infrared spectroscopy (fNIRS), particularly in the context of brain-computer interface (BCI) applications.
arxiv  

Management of hypotension in dihydropyridine calcium channel blocker overdose: The role of high‐dose insulin therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Amlodipine poisoning is a leading cause of cardiovascular medication‐related deaths, commonly managed with high‐dose insulin (HDI) therapy. However, HDI is a vasodilator that is counterproductive in managing vasoplegia. We aim to study HDI therapy in patients with hypotension following dihydropyridine calcium channel antagonist (CCA) overdose ...
Betty S. H. Chan   +3 more
wiley   +1 more source

BOLD hemodynamic response function changes significantly with healthy aging

open access: yesNeuroImage, 2019
Kathryn L. West   +7 more
semanticscholar   +1 more source

Complex hemodynamic responses to trans-vascular electrical stimulation of the renal nerve in anesthetized pigs [PDF]

open access: yesarXiv
The objective of this study was to characterize hemodynamic changes during trans-vascular stimulation of the renal nerve and their dependence on stimulation parameters. We employed a stimulation catheter inserted in the right renal artery under fluoroscopic guidance, in pigs.
arxiv  

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