Results 221 to 230 of about 187,316 (274)

Exploring the Utility of Renal Resistive Index in Critical Care: Insights into ARDS and Cardiac Failure. [PDF]

open access: yesBiomedicines
Cuttone G   +5 more
europepmc   +1 more source

Real‐world comparative effectiveness of sacubitril/valsartan versus RAS inhibition alone in patients with de novo heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Large‐scale, real‐world data on early initiation of sacubitril/valsartan in patients newly diagnosed (de novo) with HF with reduced ejection fraction (HFrEF) are limited. We examined the effectiveness of sacubitril/valsartan versus angiotensin‐converting enzyme inhibitor (ACEi)/angiotensin receptor blocker (ARB) on all‐cause and cause ...
Ankeet S. Bhatt   +6 more
wiley   +1 more source

Up‐titration of medication in patients with new‐onset heart failure with and without atrial fibrillation

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Differences in guideline‐directed medical therapy (GDMT) and clinical outcomes have been observed between heart failure (HF) patients with atrial fibrillation (AF) versus those in sinus rhythm. This study evaluated the effects of up‐titration of HF therapies, consisting of beta‐blockers, angiotensin‐converting‐enzyme inhibitors (ACEis ...
Arietje J.L. Zandijk   +6 more
wiley   +1 more source

The ADESTE trial: A phase 2 study of enibarcimab, a monoclonal antibody targeting adrenomedullin, in acute heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims This study aimed to conduct a phase 2 proof‐of‐concept and safety study to evaluate the effect of ENIBARCIMAB (EN), a non‐neutralizing humanized monoclonal antibody targeting the N‐terminus of adrenomedullin (ADM), administered immediately after stabilization with standard of care (SoC) treatment, in patients hospitalized for acute heart ...
Anggoro Budi Hartopo   +19 more
wiley   +1 more source

Impact of Elevated Intraocular Pressure on Lamina Cribrosa Oxygenation: A Combined Experimental-Computational Study on Monkeys. [PDF]

open access: yesOphthalmol Sci
Lu Y   +8 more
europepmc   +1 more source

Exercise‐induced dynamic mitral regurgitation is associated with outcomes in patients with ischaemic cardiomyopathy

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Ischaemic mitral regurgitation (MR) is a dynamic condition influenced by global and regional left ventricular remodelling as well as mitral valvular deformation. Exercise testing plays a substantial role in assessing the haemodynamic relevance of MR and is recommended by current guidelines.
Maximilian Spieker   +14 more
wiley   +1 more source

Applications of Computational Fluid Dynamics in Congenital Heart Disease: A Review. [PDF]

open access: yesJ Cardiovasc Dev Dis
Dave A   +8 more
europepmc   +1 more source

Pro‐adrenomedullin as an independent predictive biomarker for heart failure in atrial fibrillation and flutter

open access: yesESC Heart Failure, EarlyView.
Abstract Aims This study aimed to investigate potential biomarkers for predicting incident heart failure (HF) in patients with atrial fibrillation and flutter (AF and AFL), utilizing proteomic data from the UK Biobank Pharma Proteomics Project (UKB‐PPP).
Gaifeng Hu   +8 more
wiley   +1 more source

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