Results 71 to 80 of about 95,640 (249)
A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals
Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang+7 more
wiley +1 more source
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen+17 more
wiley +1 more source
Cerebral Hemodynamics and Cognitive Function in Cirrhotic Patients with Hepatic Encephalopathy
Aims. To investigate cerebral hemodynamics in cirrhotic patients with HE and to observe effects of treatment in cerebral hemodynamics and correlations among ammonia, cerebral hemodynamics, and cognitive function. Methods.
Yuqing Zhou+19 more
doaj +1 more source
Sidewall Aneurysm Geometry as a Predictor of Rupture Risk Due to Associated Abnormal Hemodynamics
Background: Hemodynamics play an important role in intracranial aneurysm (IA) initiation, growth, and rupture. Yet there remains no definitive quantitative analysis between abnormal hemodynamics and geometrical risk of IA development.Objective: The ...
Hailin Wan+7 more
doaj +1 more source
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong+16 more
wiley +1 more source
Basic Hemodynamic Changes Produced by Aortic Coarctation of Different Degrees [PDF]
TRILOK CHAND GUPTA, Carl J. Wiggers
openalex +1 more source
The study in this paper found that activating the α2A receptors of astrocytes in the thoracic spinal cord can reduce the release of inflammatory factors, thereby decreasing the necroptosis of GABAergic neurons and consequently alleviating myocardial injury caused by sepsis.
Ruilin He+9 more
wiley +1 more source
Blood and Plasma Specific Gravity Changes During Acute Alterations in Hemodynamics in Splenectomized Dogs [PDF]
J. W. Remington, C. H. Baker
openalex +1 more source