Results 231 to 240 of about 902,120 (353)

Loss of Golga7 Suppresses Oncogenic Nras‐Driven Leukemogenesis without Detectable Toxicity in Adult Mice

Advanced Science, EarlyView.
NRAS mutations are widespread in hematologic malignancies. Our study shows that GOLGA7 serves as a safe and effective therapeutic target for NRAS‐driven leukemia. Loss of Golga7 in adult mice effectively suppresses NrasG12D‐driven myeloproliferative neoplasm by disrupting its PM localization and impairing subsequent MAPK signaling, without affecting ...
Bo Jiao, Lei Yan, Rui Zhang, Wei Huang, Xinru Wang, Chenxuan Liu, Peihong Wang, Pengfei Xu, Jinzeng Wang, Zhou Fang, Donghe Li, Zhizhou Xia, Jiaoyang Li, Shiyu Ji, Qianqian Zhang, Min Wu, Shengyue Wang, Ping Liu, Ruibao Ren   +18 more
wiley   +1 more source

Clinical significance of the hemoglobin-to-red blood cell distribution width ratio in patients with severe OSAS. [PDF]

Sci Rep
Tan N, He Y, Li G, Liu P.
europepmc   +1 more source

ON DISSOCIATION AND RECOMBINATION OF HUMAN ADULT HEMOGLOBINS A, S, AND C

, 1958
Harvey A. Itano, S. J. Singer
openalex   +1 more source

THE RENAL CLEARANCE OF HEMOGLOBIN IN THE DOG [PDF]

, 1940
J. Victor Monke, Charles L. Yuile
openalex   +1 more source

Macrophage HM13/SPP Enhances Foamy Macrophage Formation and Atherogenesis

Advanced Science, EarlyView.
Previous research suggests that AIP may prevent atherogenic foamy macrophage formation. This study reveals that AIP, via its chaperone interaction with AHR, inhibits p38‐c‐JUN‐mediated transactivation of HM13, which encodes the ERAD protease HM13/SPP. HM13/SPP promotes foamy macrophage formation in addition to atherogenesis and plaque foamy macrophage ...
Yu Cao, Qirong Xie, Qiang Zheng, Jingping Zhang, Mengyu Yao, Zhongyong Du, Lujun Zhang, Tianyang Hu, Yunli Zhao, Jianlin Du, Yongyong Li, Yuxing Feng, ND Melgiri, Xiaodong Zhao, Rongzhong Huang, Yang Sun   +15 more
wiley   +1 more source

Non-canonical hemoglobin: An updated review on its ubiquitous expression. [PDF]

Redox Biol
Reed EC, Kim JD, Case AJ.
europepmc   +1 more source

Bovine Fetal Hemoglobin. I. Postnatal Persistence and Relation to Adult Hemoglobins

, 1958
R.M. Grimes, C.W. Duncan, C. A. Lassiter
openalex   +1 more source

Gut Microbiota Modulation by Inulin Improves Metabolism and Ovarian Function in Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This work proposes a novel strategy targeting gut microbiota for managing polycystic ovary syndrome (PCOS). Inulin, a gut microbiota modulator, notably boosts the growth of short‐chain fatty acids (SCFAs)‐producers, represented by Bifidobacterium, thereby improving glucolipid metabolism and ovarian function of PCOS through suppressing the inflammatory ...
Lulu Geng, Xin Yang, Jiani Sun, Ximing Ran, Dan Zhou, Mingming Ye, Li Wen, Ruirui Wang, Miaoxin Chen   +8 more
wiley   +1 more source

Preoperative Anemia Is an Independent Prognostic Factor for Esophageal Cancer Patients Who Receive Curative Treatment. [PDF]

In Vivo
Shimada K, Aoyama T, Hashimoto I, Maezawa Y, Esashi R, Fukuda M, Ju M, Yamamoto S, Kazama K, Kamiya N, Okuda N, Tamagawa A, Numata K, Uchiyama M, Saito A, Yukawa N.   +15 more
europepmc   +1 more source

SULFHYDRYL GROUPS AND THE INTERACTION BETWEEN THE HEMES IN HEMOGLOBIN [PDF]

, 1952
Austen Riggs
openalex   +1 more source