Results 301 to 310 of about 1,338,396 (378)

PPP1R3B Suppresses Atherosclerosis by Promoting the M2 Polarization of Macrophages Through Glycogen Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
PPP1R3B induces anti‐inflammatory M2 macrophage polarization and maintains energy supply in plaques. Its absence accelerates plaque progression. PPP1R3B regulates M2 macrophage polarization and energy metabolism via phosphorylated STAT3 (p‐STAT3), which plays a dual role by activating anti‐inflammatory transcriptional programs through the PPAR‐γ/PGC‐1α/
Lin Shen   +12 more
wiley   +1 more source

Inverse Co‐Design of Mechanical And Sensory Properties in Soft Lattice Foams for Multifunctional Wearables

open access: yesAdvanced Science, EarlyView.
An inverse co‐design framework integrates neural networks and physics‐based models to engineer soft lattice foams with independently tunable mechanical and sensory properties. By layering architected foams and optimizing electrode placement, this method enables multifunctional wearable sensors.
Qinghua Guan   +3 more
wiley   +1 more source

High-Resolution Genetic Profiling of Hb J-Meerut and Other Hemoglobin Variants in the Tharu Population via HPLC and DNA Sequencing. [PDF]

open access: yesDiagnostics (Basel)
Nigam N   +8 more
europepmc   +1 more source

Free‐Standing Halogen‐Bonded Nanosheets Formed by Ultrasonic Liquid Exfoliation

open access: yesAdvanced Science, EarlyView.
Free‐standing nanosheets held together by halogen bonding interactions (XB), formed through ultrasonic liquid exfoliation of layered molecular crystals, are reported here for the first time. The work challenges the conventional requirement for strong in‐layer interactions for the formation of stable nanosheets through liquid exfoliation and establishes
Prioti Choudhury Purba   +9 more
wiley   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

open access: yesAdvanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying   +6 more
wiley   +1 more source

A Novel Self‐Regulated, Non‐Directional Magnetic Thermos‐Brachytherapy 125I Seed Enhances Anticancer Efficacy by Rescuing Immune Escape

open access: yesAdvanced Science, EarlyView.
This work constructs magnetic nanoparticles (MNPs) and incorporates them with silver rods coated with 125I to form a novel composite seed, which exhibits direction‐independent and self‐regulated heating efficiency, as well as the capacity of preventing MNPs leakage and enabling repeated hyperthermia.
Bin Xu   +22 more
wiley   +1 more source

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