Results 71 to 80 of about 991,674 (261)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Selenium Intake and Glycemic Control in Young Adults With Normal-Weight Obesity Syndrome

open access: yesFrontiers in Nutrition, 2021
Numerous endogenous functions related to antioxidant processes, reproduction, and thyroid metabolism, as well as actions related to glycemic control, have been attributed to selenium.
Acsa de Castro Santos   +4 more
doaj   +1 more source

The Influence of Body Size and Hemoglobin Multiplicity on Critical Oxygen Threshold in Red Drum (Sciaenops ocellatus) [PDF]

open access: yes, 2016
Hypoxia is common in marine environments and fishes use a suite of cardiorespiratory adjustments to defend aerobic metabolism, including reducing standard metabolic rate (SMR), the minimum metabolic rate needed to sustain life at a specified temperature,
Pan, Yihang
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hemoglobin A1c Is Positively Correlated with Framingham Risk Score in Older, Apparently Healthy Nondiabetic Korean Adults [PDF]

open access: yesEndocrinology and Metabolism, 2013
BackgroundSeveral studies have suggested that elevated levels of hemoglobin A1c (HbA1c) are associated with cardiovascular disease (CVD) in nondiabetic individuals.
Ji Hye Shin   +8 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Retrospective Evaluation of Hemoglobin Variants Detected During HbA1c Testing via Capillary Electrophoresis Hemoglobin Variants Detected During HbA1c Testing

open access: yesHamidiye Medical Journal
Background: This study aimed to determine the prevalence of hemoglobin (Hb) variants detected during hemoglobin A1c (HbA1c) analysis using capillary electrophoresis and to evaluate the clinical significance of these incidental findings in the population.
Emine Feyza Yurt   +5 more
doaj   +1 more source

A structural interpretation of the acidity of groups associated with the hemes of hemoglobin and hemoglobin derivatives [PDF]

open access: yes, 1940
Since the discovery by Bohr and coworkers in 1904 of the effect of acidity on the oxygen equilibrium of hemoglobin, there have been a large number of investigations directed towards clarification of the physicochemical relationships of acid groups with ...
Coryell, Charles D., Pauling, Linus
core  

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

A Study of Lipoprotein(a) in Newly Diagnosed Type 2 Diabetes Mellitus and Its Correlation with Glycosylated Hemoglobin

open access: yesIndian Journal of Medical Specialities
Introduction: Type 2 diabetes mellitus (T2DM) is associated with an increased risk of cardiovascular disease. Lipoprotein(a) (Lp[a]) is a genetically determined lipoprotein linked with atherogenesis. This study explores the relationship between Lp(a) and
Vaibhav Shukla   +2 more
doaj   +1 more source

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