Results 191 to 200 of about 1,783,252 (315)

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo   +7 more
wiley   +1 more source

Hemoglobinopathy as a Rare Differential Disease for Low Oxygen Saturation by Pulse Oximetry: A Case Report and Literature Review. [PDF]

open access: yesIntern Med
Takeda K   +11 more
europepmc   +1 more source

Prospective validation of podoplanin expression as a diagnostic biomarker of acute promyelocytic leukemia

open access: yesCytometry Part B: Clinical Cytometry, EarlyView.
Abstract Acute promyelocytic leukemia (APL) is a medical emergency that needs immediate diagnosis and treatment. Podoplanin, a transmembrane glycoprotein that binds CLEC‐2 on platelets, was recently demonstrated to be abnormally expressed in leukemic blasts in APL, as opposed to other forms of AML, in a study using thawed primary cells.
Camilla Maria de Alencar Saraiva   +7 more
wiley   +1 more source

Newborn Screening for Sickle Cell Disease: Results from a Pilot Study in the Portuguese Population. [PDF]

open access: yesInt J Neonatal Screen
Rodrigues D   +18 more
europepmc   +1 more source

CERA Detection and Stability in Blood Versus Urine

open access: yesDrug Testing and Analysis, EarlyView.
This study presents comparative data on CERA detection in serum and urine samples, highlighting adverse analytical findings (AAFs) in serum that were undetected in corresponding urine samples. This shift would significantly improve the efficiency and sensitivity of CERA detection in doping control, ensuring more effective doping control programs ...
Olivier Salamin   +4 more
wiley   +1 more source

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