Results 181 to 190 of about 5,885,878 (288)

Shigatoxin-associated hemolytic uremic syndrome: current molecular mechanisms and future therapies

, 2012
Lindsay S Keir,1 Stephen D Marks,2 Jon Jin Kim21Academic Renal Unit, University of Bristol, Bristol; 2Department of Paediatric Nephrology, Great Ormond Street Hospital NHS Foundation Trust, London, United KingdomAbstract: Hemolytic uremic syndrome is the
Marks SD, Kim JJ, Keir LS
core  

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Hemolytic activity and antibiotic resistance profiles of <i>Staphylococcus aureus</i> isolates from clinical patients. [PDF]

Microbiol Spectr
Lai Y-H, Kao C-C, Wong MY, Huang T-Y, Lin Y-H, Chen C-W, Huang Y-K.   +6 more
europepmc   +1 more source

Hemolytic Activity in Relation to the Photosynthetic System in Chattonella marina and Chattonella ovata. [PDF]

Mar Drugs, 2021
Wu N, Tong M, Gou S, Zeng W, Xu Z, Jiang T.   +5 more
europepmc   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

SarZ inhibits the hemolytic activity through regulation of phenol soluble modulins in Staphylococcus epidermidis. [PDF]

Front Cell Infect Microbiol
Chen X, Sun H, Wang W, Wang H, Tan R, Zhu T.   +5 more
europepmc   +1 more source

A new, widespread venomous mammal species: hemolytic activity of Sorex araneus venom is similar to that of Neomys fodiens venom. [PDF]

Zoological Lett, 2022
Kowalski K, Marciniak P, Rychlik L.
europepmc   +1 more source

Kidney‐Targeted Cilastatin Nanoparticles Inhibit DPEP1‐Mediated Ferroptosis for Acute Kidney Injury Therapy

Advanced Science, EarlyView.
In this study, MPDA NPs were engineered to encapsulate CTT. To further increase renal accumulation of CTT, L‐serine was conjugated to the surface of the MPDA nanoparticles (CTT/MPDA@L‐Ser NPs). CTT/MPDA@L‐Ser NPs inhibit DPEP1 activity, thereby restoring ferroptosis defense mechanisms through upregulation of GPX4 and SLC7A11 expression, ultimately ...
Wanbing Qin, Jiaqi Huang, Manting Zhang, Wanchun Yang, Mingwei Xu, Chi Jiang, Jiekai Li, Jinjuan Wen, Qibin Huang, Shiqi Wen, Weidong Wang, Junbing He, Qinghua Liu   +12 more
wiley   +1 more source

Enhanced prediction of hemolytic activity in antimicrobial peptides using deep learning-based sequence analysis. [PDF]

BMC Bioinformatics
Abdelbaky I, Elhakeem M, Tayara H, Badr E, Abdul Salam M.   +4 more
europepmc   +1 more source

Brevibacillin 2V, a Novel Antimicrobial Lipopeptide With an Exceptionally Low Hemolytic Activity. [PDF]

Front Microbiol, 2021
Zhao X, Wang X, Shukla R, Kumar R, Weingarth M, Breukink E, Kuipers OP.   +6 more
europepmc   +1 more source