Results 91 to 100 of about 447,676 (385)

Oncologic Emergencies: Immune-Based Cancer Therapies and Complications [PDF]

, 2020
Cancer therapies have undergone several recent advancements. Current cancer treatments include immune-based therapies comprised of checkpoint inhibitors, and adoptive immunotherapy; each treatment has the potential for complications that differ from ...
Brém, Elizabeth, Koyfman, Alex, Long, Brit Jeffrey   +2 more
core  

Scalable production and biophysical characterization of an enzyme cocktail derived from human red blood cells

Biotechnology Progress, EarlyView.
Abstract Red blood cells (RBCs) play a critical role in oxygen and carbon dioxide transport, which is facilitated by RBC‐encapsulated hemoglobin (Hb) and carbonic anhydrase (CA). In addition, RBCs are constantly exposed to oxidative stress due to the intracellular reactive oxygen species (ROS) generated during Hb auto‐oxidation.
Mohd Asim Khan, Griffin J. Beyer, Naomi Goosby, Lilly Ortiz, Andre F. Palmer   +4 more
wiley   +1 more source

A case of asymptomatic pancytopenia with clinical features of hemolysis as a presentation of pernicious anemia [PDF]

Journal of Community Hospital Internal Medicine Perspectives, 2016
Pernicious anemia is an autoimmune disease with a variety of clinical presentations. We describe a case of pernicious anemia presenting with pancytopenia with hemolytic features.
Venkateswara K. Kollipara, Patrick L. Brine, David Gemmel, Sisham Ingnam   +3 more
doaj   +1 more source

Rh Negative Status and Isoimmunization Update: A Case-Based Approach to Care [PDF]

, 2003
Prior to the 1970s and the advent of Rho (D) immune globulin (RIG) for Rh negative women, hemolytic disease of the newborn led to morbidity, long-term disabilities, and mortality.
Hanson, Lisa, Harrod, Kathryn Shisler, Heywood, Patricia, VandeVusse, Leona   +3 more
core   +1 more source

Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes. [PDF]

, 2009
BackgroundA growing number of realistic in silico models of metabolic functions are being formulated and can serve as 'dry lab' platforms to prototype and simulate experiments before they are performed.
Jamshidi, Neema, Palsson, Bernhard O
core   +3 more sources

Hemolysis Detected Following the Preparation and Collection of Blood in a Porcine Model Using a Syringe‐Based Aspiration Thrombectomy System for Autotransfusion

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Autologous transfusion of filtered, unwashed blood is a technique to mitigate the effects of blood loss during mechanical thrombectomy, but the degree of hemolysis resulting from this approach and guidance for blood return in this setting is not well understood.
Suhail Dohad, Mohammed M. Hoque, Jonathan H. Waters, Marc Salhanick   +3 more
wiley   +1 more source

Diagnostic approaches for inherited hemolytic anemia in the genetic era

Blood Research, 2017
Inherited hemolytic anemias (IHAs) are genetic diseases that present with anemia due to the increased destruction of circulating abnormal RBCs. The RBC abnormalities are classified into the three major disorders of membranopathies, hemoglobinopathies ...
Yonggoo Kim, Joonhong Park, Myungshin Kim   +2 more
semanticscholar   +1 more source

Characterisation of the Immunophenotype of Dogs with Primary Immune-Mediated Haemolytic Anaemia [PDF]

, 2016
Immune-mediated haemolytic anaemia (IMHA) is reported to be the most common autoimmune disease of dogs, resulting in significant morbidity and mortality in affected animals.
A Corato, A Doganci, A Knueppel, A Kojima, A Mqadmi, A Saxena, A Zanella, AL Rivas, AM Hall, AM Hall, B Sadlack, Barbara Glanemann, CA Lawson, CJ Elson, CJ Piek, CL Bennett, D Cao, D Pinheiro, DM Willerford, Douglas Thamm, E Ahmad, E Fagiolo, E Fagiolo, E Fagiolo, E Fagiolo, E von Elm, FJ Ward, G Kleiner, HF Titmarsh, James W. Swann, JH Buckner, JM Kim, JS Ellis, JW Swann, K Wing, KD Mitchell, Kelly Woods, KY King, L Han, L Llorente, L Llorente, L Xu, M Kjelgaard-Hansen, M Miyara, M Murai, MA Miller, ME Brunkow, NJ Davidson, NV Giltiay, OA Garden, Oliver A. Garden, P Pietschmann, PM McManus, RN Barker, RS Wildin, S Aggarwal, S Berentsen, S Lindley, S McCullough, S Sakaguchi, SA Bustin, SJ Ireland, V Viglietta, X Valencia, Ying Wu, Z Jiao   +65 more
core   +11 more sources

Don’t neglect the non-thrombotic manifestations of antiphospholipid syndrome in children – autoimmune hemolytic anemia and myocarditis: a case report and literature review

Frontiers in Immunology
Antiphospholipid Syndrome (APS) is a systemic autoimmune disorder characterized by persistent antiphospholipid antibodies, associated with thrombosis or adverse pregnancy outcomes.
Wanlin Cui, Yuming Sun, Danyang Zhao, Masumeh Nozzari Varkani, Guan Wang, Xiaoqing Wen, Mingyue Shi, Xiaohan Wang, Xinyi Zhang, Hongkun Jiang   +9 more
doaj   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source