Results 291 to 300 of about 424,378 (382)

Peripheral Multilineage Haemophagocytosis in an Extremely Premature Infant With Escherichia coli Sepsis

eJHaem, Volume 6, Issue 4, August 2025.
Jorik H. Amesz, Richard M. Noordervliet, Madeleen Bosma   +2 more
wiley   +1 more source

The Association of Serum Level of TGF‐β1 and Clinical Manifestations in Sickle Cell Anemia: A Case‐Control Study

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Sickle cell anemia (SCA) is an inherited red blood cell disorder resulting from the polymerization of Hemoglobin S. Acute vaso‐occlusive crisis and multiple organ damage are the most common complications of SCA. Because of its multifunctional role in inflammation, endothelial dysfunction, and fibrosis, TGF‐β1 could be ...
Fatemeh Bakhshipour, Bita Bandar, Fatemeh Bineshfar, Najmeh Nameh Goshay Fard, Azar Babaahmadi, Najmaldin Saki, Kaveh Jaseb   +6 more
wiley   +1 more source

Crovalimab: A Novel Approach in the Management of Paroxysmal Nocturnal Hemoglobinuria

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aims Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare acquired clonal blood disorder caused by mutations in the PIGA gene, leading to complement‐mediated hemolysis. Currently available terminal complement inhibitors, such as Eculizumab and Ravulizumab, pose several challenges, including the need for frequent intravenous ...
Laiba Jalal, Marium Ahmed, Anum Khalid
wiley   +1 more source

Prevalence of systemic lupus erythematosus in autoimmune hemolytic anemia patients based on coombs test results. [PDF]

Eur J Med Res
Harahap RIM, Ardiningrum T, Pamela Y, Widiasta A, Rossanti R, Bethasari M.   +5 more
europepmc   +1 more source

Polymorphic Distribution of Human Homeostatic Iron Regulator Gene H63D rs1799945 and Clinico‐Hematological Parameters of Sickle Cell Anemia Patients: A Case‐Control Study in Northern Ghana

Health Science Reports, Volume 8, Issue 7, July 2025.
ABSTRACT Background and Aim The study assessed the polymorphic distribution of H63D rs1799945 of HFE gene and clinico‐hematological parameters of SCA patients. Methods Sixty sickle cell anemia (SCA) patients and 30 healthy controls without sickle cell disease between the ages of 2–38 years were selected for this case‐control study from March to July ...
Samuel Kwasi Appiah, Charles Nkansah, Samira Daud, Gabriel Abbam, Felix Osei‐Boakye, Larry Adom, Rekhiatu Oboirien Abdul Rauf, Godfred Takyi Addae, Lydia Sarpong, Godfred Amoah Appiah, Charles Agnaatah Derigubah, Jennifer Obeng Mensah, Onwuka Chima Kalu, Victor U. Usanga, Boniface Nwofoke Ukwah, Ejike Felix Chukwurah   +15 more
wiley   +1 more source

Co-occurrence of acute hemolytic anemia and methemoglobinemia in a 74-year-old female with G6PD deficiency: A case report. [PDF]

Medicine (Baltimore)
Chen B, Han Y.
europepmc   +1 more source

Macrophage Signaling Pathways in Health and Disease: From Bench to Bedside Applications

MedComm, Volume 6, Issue 7, July 2025.
Macrophage functions in phagocytosis, tissue repair, immune regulation, and neuronal network protection. And graphic abract image in the attachment. ABSTRACT Macrophages exhibit remarkable functional plasticity by dynamically polarizing into proinflammatory or antiinflammatory subsets in response to microenvironmental cues. This duality underpins their
Yongquan Chi, Haipeng Jiang, Yiyuan Yin, Xinyu Zhou, Yiyouyou Shao, Yongsheng Li, Jianhua Rao   +6 more
wiley   +1 more source

Long-Term Outcomes of Rituximab Therapy in Autoimmune Hemolytic Anemia: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Rizwanullah U, Abifaraj A, Shah S, Kausar R, Hummad H, Portillo Muñoz CA, Hyderi FA, Chi Gomez LA, Urbina R, Niftalieva G, Vasquez Zelaya ED, Faraj M.   +11 more
europepmc   +1 more source

Autoimmune Diseases: Molecular Pathogenesis and Therapeutic Targets

MedComm, Volume 6, Issue 7, July 2025.
This review provides a comprehensive overview of common autoimmune diseases, details clinical manifestations and summarizes the pathogenesis, including the breakdown of immune tolerance, initiation of autoimmune responses, and their progressive amplification.
Xiaoshuang Song, Hantian Liang, Fang Nan, Wenjing Chen, Junyao Li, Liu He, Yiping Cun, Zhenhong Li, Wei Zhang, Dunfang Zhang   +9 more
wiley   +1 more source