Results 121 to 130 of about 9,064,819 (381)

Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics

open access: yesAdvanced Science, EarlyView.
Intestinal barrier stability is vital for gut health. Plastic polyethylene terephthalate (PET) disrupts this barrier, causing inflammation and infections. This study encodes transforming growth factor‐β into EcN and modifies its surface with pH‐responsive polymer (EcNT@L), creating an oral drug delivery system to repair nano PET‐induced intestinal ...
Wenxin Chen   +9 more
wiley   +1 more source

Increasing the Discovery Power and Confidence Levels of Disease Association Studies: A Survey [PDF]

open access: yesarXiv, 2017
The majority of common diseases are influenced by multiple genetic and environmental factors such as Cancer. Even though uncovering the main causes of disease is deemed difficult due to the complexity of gene-gene and gene-environment interactions, major research efforts aim at identifying disease risk factors, especially genetic ones.
arxiv  

Hereditary Nonspherocytic Hemolytic Disease [PDF]

open access: bronze, 1954
Arno G. Motulsky   +2 more
openalex   +1 more source

Inhalable Polymeric Nanoparticle Containing Triphenylphosphanium Bromide‐modified Sonosensitizer for Enhanced Therapy of Acute Bacterial Pneumonia

open access: yesAdvanced Science, EarlyView.
Bacterial pneumonia is the sixth leading cause of death. In this study, an inhalable polymeric nanoparticle NPFCPS‐P is developed, which under US stimulation showed high efficacy in the treatment of acute bacterial pneumonia. This nanoplatform would be much less prone to select bacterial resistance and represented a promising measure for antibiotics ...
Lin Wang   +6 more
wiley   +1 more source

The development of nations conditions the disease space [PDF]

open access: yesarXiv, 2019
Using the economic complexity methodology on data for disease prevalence in 195 countries during the period of 1990-2016, we propose two new metrics for quantifying the relatedness between diseases, or the `disease space' of countries. With these metrics, we analyze the geography of diseases and empirically investigate the effect of economic ...
arxiv  

Radio‐Activated Selenium‐Doped Janus Ag/Ag2SexSy Nanoparticles for Precise Cancer NIR‐II Fluorescence Imaging and Radiosensitization Therapy

open access: yesAdvanced Science, EarlyView.
A new kind of selenium‐doped Ag/Ag2S Janus nanoparticles (Ag/Ag2SexSy JNPs) is reported as radio‐responsive probes for specifically hydrogen peroxide (H2O2)‐activated cancer imaging and enhanced radiosensitization, offering a promising approach for precision cancer theranostics.
Kang Zhu   +12 more
wiley   +1 more source

Paroxysmal Nocturnal Hemoglobinuria

open access: yesJournal of Nepal Medical Association, 2005
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hemolytic disorder of acquired origin and is clinically manifested by chronic hemolysis, thromboses in various sites, and bone marrow failure.
Buddhi P Paudyal   +4 more
doaj   +1 more source

CO‐Releasing Polyoxometalates Nanozyme with Gut Mucosal Immunity and Microbiota Homeostasis Remodeling Effects for Restoring Intestinal Barrier Integrity

open access: yesAdvanced Science, EarlyView.
A CO‐releasing polyoxometalates nanozyme (PMC) is engineered by coordinating pentacarbonyl manganese bromide with molybdenum‐based polyoxometalates nanoclusters. PMC exhibits targeted accumulation at IBD sites, efficient ROS scavenging, and responsive CO release.
Hongyang Lu   +16 more
wiley   +1 more source

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