Results 291 to 300 of about 9,064,819 (381)

Ruthenium Nanozyme@Magnesium silicate nanosheets encapsuled in microneedle patches promote repair of radiation‐induced skin defects by remodeling pathological environment

open access: yesInterdisciplinary Medicine, EarlyView.
In this work, we introduce a novel composite microneedle (MN) patch that integrates ruthenium‐loaded magnesium silicate nanosheets (MSR) as a multifaceted therapeutic platform with oxidative stress mitigation, ROS generation inhibition and cellular signaling pathways restoration for treating RISD.
Zhongyi Sun   +11 more
wiley   +1 more source

Chronic non-spherocytic hemolytic anemia associated with severe neurological disease due to -glutamylcysteine synthetase deficiency in a patient of Moroccan origin

open access: gold, 2007
Myra Pereira   +9 more
openalex   +2 more sources

Subchronic Inhalation of TiO2 Nanoparticles Leads to Deposition in the Lung and Alterations in Erythrocyte Morphology in Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT TiO2 nanoparticles (NPs) are extensively used in various applications, highlighting the importance of ongoing research into their effects. This work belongs among rare whole‐body inhalation studies investigating the effects of TiO2 NPs on mice.
Pavel Kulich   +12 more
wiley   +1 more source

Hemolytic Disease of the Newborn Associated with Anti-JraAlloimmunization in a Twin Pregnancy: The First Case Report in Korea

open access: hybrid, 2010
Hyungsuk Kim   +6 more
openalex   +2 more sources

A Review of In Silico and In Vitro Approaches in the Fight Against Carbapenem‐Resistant Enterobacterales

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This review highlights computational approaches for discovering antimicrobials against carbapenem‐resistant Enterobacterales. It outlines methods like pharmacophore modeling, molecular docking, and absorption, distribution, metabolism, and excretion–toxicity (ADMET) analysis, integrated with in vitro assays, to identify and validate potential drugs ...
Muhammad Absar   +7 more
wiley   +1 more source

Indication‐Specific Dosing and Dose‐Evaluation Strategies in New Indications for Non‐Oncology Monoclonal Antibodies

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Compared to traditional small molecule drugs, monoclonal antibodies (mAbs) often display more complex pharmacokinetic (PK) and pharmacodynamic (PD) properties that may be impacted by disease‐specific factors. For mAbs in non‐oncology indications, where the same drug might be used for conditions involving different organ systems and/or having ...
Sherouk M. Tawfik, Fei Tang
wiley   +1 more source

Operative and nonoperative management of acute cholecystitis in patients on chronic kidney replacement therapy

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Patients with kidney failure receiving chronic kidney replacement therapy (KRT: dialysis or kidney transplantation) have increased risks of postoperative mortality and morbidity. This study assesses the outcomes of acute cholecystitis in patients on chronic KRT who undergo cholecystectomy compared to nonoperative management ...
Dharmenaan Palamuthusingam   +8 more
wiley   +1 more source

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