Results 41 to 50 of about 9,064,819 (381)
Frontiers in PediatricsPatients with hemolytic diseases are at increased risk for gallstone-related complications. Modified scoring systems have been developed to assess which pediatric patients would benefit from endoscopic retrograde cholangiopancreatography (ERCP) to treat ...
Jennifer Thompson +20 more
doaj +1 more source
Mixed cationic liposomes for brain delivery of drugs by the intranasal route: the acetylcholinesterase reactivator 2-PAM as encapsulated drug model [PDF]
Colloids and Surfaces B: Biointerfaces, 171, 358-367 (2018), 2018 New mixed cationic liposomes based on L-{\alpha}-phosphatidylcholine and dihexadecylmethylhydroxyethylammonium bromide (DHDHAB) were designed to overcome the BBB crossing by using the intranasal route. Synthesis and self-assembly of DHDHAB were performed.
arxiv +1 more source
A New Strategy for the Morphological and Colorimetric Recognition of Erythrocytes for the Diagnosis of Forms of Anemia based on Microscopic Color Images of Blood Smears [PDF]
International journal of advanced computer science and
applications (IJACSA), 2020, 11 (7), pp.488-497, 2023 The detection of red blood cells based on morphology and colorimetric appearance is very important in improving hematology diagnostics. There are automatons capable of detecting certain forms, but these have limitations with regard to the formal identification of red blood cells because they consider certain cells to be red blood cells when they are ...
arxiv
Blood, 2019 Cold agglutinin disease is a difficult-to-treat autoimmune hemolytic anemia in which immunoglobulin M antibodies bind to erythrocytes and fix complement, resulting in predominantly extravascular hemolysis.
U. Jäger +13 more
semanticscholar +1 more source
Forecasting Disease Burden In Philippines: A Symbolic Regression Analysis [PDF]
arXiv, 2021 Burden of disease measures the impact of living with illness and injury and dying prematurely and it is increasing worldwide leading cause of death both global and national. This paper aimed to propose an index of diseases and evaluate a mathematical model to describe the number of burden of disease by cause in the Philippines from 1990 - 2016. Through
arxiv
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Coronavirus Disease 2019 (COVID-19) Associated Hemolytic Uremic Syndrome in a Toddler
Case Reports in Pediatrics, 2022 Coronavirus disease 2019 (COVID-19) is a heterogenous, predominantly pulmonary disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has resulted in catastrophic illness around the world.
Kristie Searcy +3 more
doaj +1 more source
Blood, 2018 Transfusions can be a life-saving treatment of patients with sickle-cell disease (SCD). However, availability of matched units can be limiting because of distinctive blood group polymorphisms in patients of African descent.
F. Pirenne, K. Yazdanbakhsh
semanticscholar +1 more source
Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding
FEBS Open Bio, EarlyView.The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla +4 more
wiley +1 more source
NEUROLOGICAL COMPLICATIONS IN PATIENTS WITH TYPICAL HEMOLYTIC UREMIC SYNDROME [PDF]
Archives of the Balkan Medical Union, 2020 Introduction. Hemolytic uremic syndrome (HUS) is a hemorrhagic systemic microangiopathy, which primarily affects the kidney and is defined by the triad: acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia.
Mariana COSTIN +3 more
doaj +1 more source