Results 61 to 70 of about 9,064,819 (381)

Ontology Based Information Extraction for Disease Intelligence [PDF]

open access: yesInternational Journal of Research in Computer Science, 2 (6): pp. 7-19, November 2012. doi:10.7815/ijorcs.26.2012.051, 2012
Disease Intelligence (DI) is based on the acquisition and aggregation of fragmented knowledge of diseases at multiple sources all over the world to provide valuable information to doctors, researchers and information seeking community. Some diseases have their own characteristics changed rapidly at different places of the world and are reported on ...
arxiv   +1 more source

Optimal management of atypical hemolytic uremic disease: challenges and solutions

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2019
Atypical hemolytic uremic syndrome (aHUS) is a chronic life threatening condition that arises from genetic abnormalities resulting in uncontrolled complement amplifying activity.
R. Raina   +6 more
semanticscholar   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq   +4 more
wiley   +1 more source

Coexistent sickle cell anemia and autoimmune hemolytic anemia in two adolescents [PDF]

open access: yesEinstein (São Paulo)
The development of alloantibodies or autoantibodies is a complication observed in sickle cell disease. Autoimmunization occurs in 7.6-12% of chronically or intermittently transfused patients with sickle cell disease; however, the clinical implications of
Vinícius Reis Soares   +3 more
doaj   +1 more source

Diagnosis and treatment of severe hemolytic disease of the fetus and newborn: a 10‐year nationwide retrospective study

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2015
Outcome after intrauterine transfusions due to severe hemolytic disease of the fetus and newborn.
S. Sainio   +12 more
semanticscholar   +1 more source

Formulation and Characterization of Novel Ionizable and Cationic Lipid Nanoparticles for the Delivery of Splice‐Switching Oligonucleotides

open access: yesAdvanced Materials, EarlyView.
Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu   +9 more
wiley   +1 more source

Pattern of AST and ALT changes in Relation to Hemolysis in sickle cell Disease

open access: yesClinical Medicine Insights: Blood Disorders, 2011
Background Elevated aminotransferase levels are commonly associated with compromised hepatic integrity from various insults. In sickle cell disease, aspartate transaminase (AST) is also released via intravascular hemolysis.
K. Nsiah   +5 more
doaj   +1 more source

Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis

open access: yesVeterinary Research, 2021
Riemerella anatipestifer causes epizootic infectious disease in poultry resulting in serious economic losses especially to the duck industry. In our previous study, R. anatipestifer was found to lyse duck erythrocytes in vitro.
Bingqing Sun   +9 more
doaj   +1 more source

Estimating the Risk of ABO Hemolytic Disease of the Newborn in Lagos

open access: yesJournal of Blood Transfusion, 2015
Background. ABO hemolytic disease of the newborn is the most common hemolytic consequence of maternofetal blood group incompatibility restricted mostly to non-group-O babies of group O mothers with immune anti-A or anti-B antibodies. Aim.
A. Akanmu   +3 more
semanticscholar   +1 more source

Materials Advances in Devices for Heart Disease Interventions

open access: yesAdvanced Materials, EarlyView.
This review examines the crucial role of materials in heart disease interventions, focusing on strategies for monitoring, managing, and repairing heart conditions. It discusses the material requirements for medical devices, highlighting recent innovations and their impact on cardiovascular health.
Gagan K. Jalandhra   +11 more
wiley   +1 more source

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