Results 151 to 160 of about 69,645 (303)

Understanding supply sustainability of plasma‐derived medicinal products: Drivers and consequences of shortages

open access: yesVox Sanguinis, EarlyView.
Abstract Plasma‐derived medicinal products (PDMPs), particularly immunoglobulins (Igs), are essential treatments for numerous diseases, often serving as the primary therapeutic option and playing a critical role in patient care. The human origin of these products, however, can lead to supply constraints due to a lack of plasma collection, market ...
Miriam Belmonte   +4 more
wiley   +1 more source

Genome-Wide Association Studies in Myocardial Infarction and Coronary Artery Disease

open access: yesJournal of Tehran University Heart Center, 2010
Myocardial infarction (MI) and its major determinant, coronary artery disease (CAD), are complex diseases arising from the interaction between several genetic and environmental factors.
Pier Mannucci   +2 more
doaj  

Prevalence of Hemophilia and Clinicodemographic Characteristics of Hemophilic Patients Aged ≤ 18 Years in Thi-Qar, Iraq

open access: yesGlobal Pediatric Health
Objectives . This study aims to determine the prevalence of hemophilia in Thi-Qar, Iraq and study clinical and demographic characteristics of patients with hemophilia. Methods .
Ghada Mansoor Abood FICMS   +2 more
doaj   +1 more source

Techno‐Economic Analysis of Membrane‐Based Purification Platforms for AAV Vector Production

open access: yesBiotechnology and Bioengineering, Volume 122, Issue 9, Page 2400-2409, September 2025.
ABSTRACT Technologies for large‐scale manufacturing of viral vectors for gene therapies, such as tangential flow filtration and membrane chromatography, are under development. In these early stages of process development, techno‐economic analyses are useful for identifying membrane properties yielding the greatest impact on process performance. In this
Juan J. Romero   +6 more
wiley   +1 more source

Pennsylvania state-wide hemophilia program: summary of immediate reactions with the use of factor VIII and factor IX concentrate [PDF]

open access: bronze, 1979
David Prager   +8 more
openalex   +1 more source

Emicizumab Prophylaxis in Hemophilia A with Inhibitors

open access: yesNew England Journal of Medicine, 2017
J. Oldenburg   +14 more
semanticscholar   +1 more source

Effectiveness of Pyridoxal‐5′‐Phosphate in PNPO Deficiency: A Systematic Review

open access: yesJournal of Inherited Metabolic Disease, Volume 48, Issue 5, September 2025.
ABSTRACT Pyridox(am)ine 5′‐phosphate oxidase (PNPO) deficiency is an ultrarare inherited neurometabolic disease, characterized by primarily neonatal‐onset B6‐responsive epileptic encephalopathies. Treatment often requires sustainable access to high‐quality pyridoxal‐5′‐phosphate (PLP, i.e., active vitamin B6), although some patients (also) respond to ...
Nina N. Stolwijk   +7 more
wiley   +1 more source

CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022)

open access: yesBleeding, Thrombosis and Vascular Biology
Background and Aims: Intracerebral hemorrhage (ICH) is a severe and life-threatening complication in patients with hemophilia, often resulting in high mortality and long-term neurological impairment.
doaj   +1 more source

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