Results 151 to 160 of about 83,381 (315)

Relationship between Dose, Factor IX Activity Levels and Bleeding Probability for rIX‐FP Prophylaxis in Hemophilia B: A Repeated Time‐to‐Event Analysis

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 4, Page 831-840, October 2025.
In hemophilia B, pharmacokinetic (PK)‐guided dosing of extended half‐life factor IX (EHL‐FIX) concentrates can secure targeted FIX exposure. Target FIX activity levels in plasma should be individually set primarily taking bleeding tendency into account, alongside the presence of target joints, physical activity, and preferred dosing schedules. In other
Sjoerd F. Koopman   +4 more
wiley   +1 more source

Overview of Patients with Hemophilia in China: Demographics, Diseases, Treatment, and Health Status

open access: yesPatient Preference and Adherence
Luying Zhang,1,* Peng Zhang,2,* Wen Chen1 1School of Public Health, Fudan University, Shanghai, 200032, People’s Republic of China; 2School of Humanities, Shanghai Institute of Technology, Shanghai, 201418, People’s Republic of China*These ...
Zhang L, Zhang P, Chen W
doaj  

CO27 | Intracerebral hemorrhage in hemophilia A and B: a 10-year prospective multicenter study in Italy (2012–2022)

open access: yesBleeding, Thrombosis and Vascular Biology
Background and Aims: Intracerebral hemorrhage (ICH) is a severe and life-threatening complication in patients with hemophilia, often resulting in high mortality and long-term neurological impairment.
doaj   +1 more source

Endoscopic Vascular Grading Directs Stepwise Therapy in Hereditary Hemorrhagic Telangiectasia

open access: yesLaryngoscope Investigative Otolaryngology, Volume 10, Issue 5, October 2025.
This study introduces a novel endoscopic vascular grading system for HHT. The system is inspired by intergenerational family observations and correlates with epistaxis severity. It guides personalized therapy based on grade, offering simplicity and clinical utility.
Hong‐Gang Duan   +5 more
wiley   +1 more source

International Perspectives on Vitamin K Deficiency Bleeding in Infants: A Cross‐Sectional Questionnaire‐Based Survey

open access: yesPediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Purpose Vitamin K deficiency bleeding (VKDB) can occur in neonates and infants due to low placental transfer and storage of VK. Although the incidence has decreased with global VK prophylaxis at birth, VKDB remains a concern. This study aimed to assess the recent magnitude, risk factors, and outcomes of VKDB and barriers/limitations to VK ...
Nongnuch Sirachainan   +16 more
wiley   +1 more source

PB2654: RARE BLEEDING DISORDERS: LONG-TERM EXPERIENCE FROM A HEMOPHILIA CENTER

open access: yesHemaSphere, 2023
Antonios Meimaridis   +5 more
doaj   +1 more source

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