Results 261 to 270 of about 69,645 (303)
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Establishing the Prevalence and Prevalence at Birth of Hemophilia in Males
Annals of Internal Medicine, 2019Hemophilia is caused by a mutation in either the F8 (hemophilia A) or F9 (hemophilia B) gene and results in substantive morbidity and mortality if not treated.
A. Iorio +6 more
semanticscholar +1 more source
Hematology/Oncology Clinics of North America, 1992
Over the past few years considerable progress has been made in elucidating the molecular genetics of hemophilia A, in carrier detection and prenatal diagnosis, and in the production of safer clotting factor concentrates. Recombinant FVIII, shown to be safe and effective in ongoing prelicensure clinical trials that began in the spring of 1987, should ...
J M, Lusher, I, Warrier
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Over the past few years considerable progress has been made in elucidating the molecular genetics of hemophilia A, in carrier detection and prenatal diagnosis, and in the production of safer clotting factor concentrates. Recombinant FVIII, shown to be safe and effective in ongoing prelicensure clinical trials that began in the spring of 1987, should ...
J M, Lusher, I, Warrier
openaire +2 more sources
Pediatric Clinics of North America, 1980
The clinical manifestations of hemophilia depend upon both age and the severity of the factor VIII or IX deficiency. Hemophilia A and B cannot be differentiated on clinical grounds. Laboratory tests include platelet count, prothrombin time, partial thromboplastin time, and bleeding time.
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The clinical manifestations of hemophilia depend upon both age and the severity of the factor VIII or IX deficiency. Hemophilia A and B cannot be differentiated on clinical grounds. Laboratory tests include platelet count, prothrombin time, partial thromboplastin time, and bleeding time.
openaire +2 more sources
Blood Coagulation in Hemophilia A and Hemophilia C
Blood, 1998Tissue factor (TF)-induced coagulation was compared in contact pathway suppressed human blood from normal, factor VIII-deficient, and factor XI-deficient donors. The progress of the reaction was analyzed in quenched samples by immunoassay and immunoblotting for fibrinopeptide A (FPA), thrombin-antithrombin (TAT), factor V activation, and osteonectin ...
J B Lock +5 more
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A Challenge for Hemophilia Treatment: Hemophilia and Cancer
Journal of Pediatric Hematology/Oncology, 2020Background: The risk of developing cancer increases with age and also adverse environmental conditions. The same holds true in the aging people with hemophilia (PwH). Furthermore, cancer is an important challenge for physicians working in multidisciplinary hemophilia care centers. Aim:
Basak Koc, Bulent Zulfikar
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JAMA: The Journal of the American Medical Association, 1983
Reproduction rates in 294 men with severe hemophilia, 327 of their mothers, and 215 of their sisters were compared with Vital Statistics data for the general US population matched for exact age, calendar year between 1940 and 1977, and, for women, parity.
Robert B. Francis, Carol K. Kasper
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Reproduction rates in 294 men with severe hemophilia, 327 of their mothers, and 215 of their sisters were compared with Vital Statistics data for the general US population matched for exact age, calendar year between 1940 and 1977, and, for women, parity.
Robert B. Francis, Carol K. Kasper
openaire +3 more sources
2011
Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs.
Franchini M, LIPPI, Giuseppe
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Acquired hemophilia A is a rare but often life-threatening hemorrhagic disorder characterized by an autoantibody directed against coagulation factor VIII. Fifty per cent of cases are idiopathic whereas the remaining 50% are associated with pregnancy, autoimmune conditions, malignancies and drugs.
Franchini M, LIPPI, Giuseppe
openaire +3 more sources
The World Federation of Hemophilia Annual Global Survey 1999‐2018
Haemophilia, 2020The World Federation of Hemophilia (WFH) strives to achieve care for all patients with inherited bleeding disorders through research, advocacy, capacity building and education.
Jeffrey S. Stonebraker +10 more
semanticscholar +1 more source
Pseudotumor of hemophilia in the mandible of a patient with hemophilia A
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2012Hemophilic pseudotumor is a rare lesion that is essentially a progressive, slowly expanding, encapsulated hematoma. It is estimated to affect 1% to 2% of severe hemophiliacs. The majority of hemophilic pseudotumors occur within soft tissues (intramuscular) and long bones of adult males. Fewer than 20 cases have been reported in the maxillofacial region.
Roger R. Throndson +3 more
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2013
Recent advances in the management of patients with hemophilia have led to significantly improved outcomes. Transmission of infectious diseases through blood product administration and severe arthropathies from recurrent joint bleeds are now rare.
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Recent advances in the management of patients with hemophilia have led to significantly improved outcomes. Transmission of infectious diseases through blood product administration and severe arthropathies from recurrent joint bleeds are now rare.
openaire +1 more source