RBMS1, an RNA‐binding protein, restores vascular endothelial homeostasis by enhancing ATG3‐mediated autophagy, thereby attenuating thrombus formation and suggesting a potential avenue for further therapeutic exploration in DVT. ABSTRACT Deep vein thrombosis (DVT) is a prevalent vascular disorder characterized by aberrant coagulation within the deep ...
Chu Chu +13 more
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Hemorrhagic brain abscess mimicking an intracranial neoplasm in invasive Klebsiella pneumoniae syndrome: illustrative case. [PDF]
Suzuki Y +8 more
europepmc +1 more source
Design and Application of Nanozymes: Current Trends and Cutting‐Edge Breakthroughs
Advanced Science, EarlyView.
Kelong Fan, Hui Wei, Xiyun Yan
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Potential of Nanoparticle‐Based Phototherapies for Future Treatment of Uveal Melanoma
This review evaluates nanoparticle‐based phototherapies for uveal melanoma, highlighting emerging strategies to enhance tumor targeting, light delivery, and treatment precision. Preclinical data indicate improved efficacy and reduced toxicity, supporting their potential to enhance localized treatment and future translational advances. (Generated by the
Emilie Lambert +8 more
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Hemorrhagic Cystitis With Bladder Tamponade Associated With <i>Morganella morganii</i> in an Older Patient Without Recent Catheterization. [PDF]
Kawaguchi Y.
europepmc +1 more source
Scleral buckle hemorrhagic cyst masquerading as an orbital tumor
David RP Almeida,1 Eric K Chin,1 H Culver Boldt,1 Vinit B Mahajan1,2 1Department of Ophthalmology and Visual Sciences; 2Omics Laboratory, University of Iowa Hospitals and Clinics, Iowa City, IA, USA Abstract: We present a case of a 41-year-old man who ...
Mahajan VB +3 more
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Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke +10 more
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Clinical characteristics associated with gastrointestinal bleeding in neonates with laboratory-confirmed norovirus gastroenteritis. [PDF]
Zhu L +5 more
europepmc +1 more source
Analysis of Risk Factors for Hemorrhagic Transformation of Cerebral Infarction and Recurrence of Cerebral Infarction: A Retrospective Study on Cerebral Infarction Patients with or without Hemorrhagic Transformation [PDF]
Pengnan Bao,1 Ling Ling,2 Lei Xiang,2 Xueqing Liu,1 Jinwei Zhang,1 Wei Yue1,2 1Clinical College of Neurology, Neurosurgery and Neurorehabilitation, Tianjin Medical University, Tianjin, 300000, People’s Republic of China; 2Department of Neurology, Tianjin
Liu X +5 more
core
Uhrf1‐mediated PKM2 ubiquitination and degradation repressed the nuclear translocation of PKM2, and EPT served as a molecular glue capable of targeting the Uhrf1–PKM2 complex to alleviate the IBD course, suggesting that the Uhrf1–PKM2 axis was a previously unrecognized strategy for treating IBD.
Juan Zhang +9 more
wiley +1 more source

