Results 211 to 220 of about 583,715 (337)

Prolonged delayed vasospasm in the setting of nonaneurysmal intraventricular hemorrhage

open access: green, 2019
David Altschul   +4 more
openalex   +2 more sources

Ocular Hemorrhages

open access: yesCleveland Clinic Journal of Medicine, 1947
openaire   +2 more sources

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

open access: yesAdvanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong   +11 more
wiley   +1 more source

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation

open access: yesAdvanced Science, EarlyView.
Microglial AXL drives white matter repair after stroke by orchestrating the cleanup of myelin debris. Mechanistically, AXL signals through EGR1 to boost Smpd1 transcription, regulating sphingolipid metabolism and preventing lipid droplet toxicity. Restoring the pathway with ASM therapy mitigates damage, positioning AXL as a key node for therapeutic ...
Junqiu Jia   +13 more
wiley   +1 more source

Delayed Parenchymal Hemorrhage Following Successful Embolization of Brainstem Arteriovenous Malformation -Case Report-

open access: gold, 2010
Yusuke Morihiro   +7 more
openalex   +2 more sources

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